SNP Report

Basic Info

Name	rs11074070 dbSNP Ensembl
Location	chr15:92423596 - 92423596(1)
Variant Alleles	T/G
Ancestral Allele	T
Minor Allele	G
Minor Allele Frequence	0.459864
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000557166); intron_variant(ENST00000268164, ENST00000539113, ENST00000555434)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
McAuley, E. Z., 2012	C/A		P-value = 0.036, Empirical P-value = 0.04, OR (95% CI)=0.73 ...... P-value = 0.036, Empirical P-value = 0.04, OR (95% CI)=0.73 (0.55-0.98) in the Australian bipolar disorder cohort More...	Nominally significant association (P < 0.05) was found with ...... Nominally significant association (P < 0.05) was found with 18 SNPs. Association with 14 of these SNPs held true when empirical P values were obtained through 10, 000 replicate permutations. More...	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	15q26	2(2/0/0)
ENO1P2	enolase 1, (alpha) pseudogene 2	15q26.1	Mapped by Literature SNP

SNPs in LD with rs11074070 (count: 0) View in gBrowse (chr15:92423596..92423596 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
McAuley, E. Z., 2012	P-value > 0.075	Single SNP analysis did not yield significant evidence for association.	Negative

Overlap with MDD from cross-disorder studies (count: 0)