BDgene

SNP Report

Basic Info
Name rs9470080 dbSNP Ensembl
Location chr6:35678658 - 35678658(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele T
Minor Allele Frequence 0.363419
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000357266, ENST00000536438, ENST00000539068, ENST00000542713)
No. of Studies 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? YES

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Szczepankiewicz A., 2014 C/T P-value=0.471 P-value=0.471 Our main finding is no association with bipolar disorder. Our main finding is no association with bipolar disorder. Negative
Ceulemans, S.,2011 T/C Single SNP analyses: Permuted P-value = 0.6635, Odds Ratio=1...... Single SNP analyses: Permuted P-value = 0.6635, Odds Ratio=1.054 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
FKBP5 FK506 binding protein 5 6p21.31 5(1/4/0)

SNPs in LD with rs9470080 (count: 10) View in gBrowse (chr6:35599983..35707068 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 10)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Szczepankiewicz A., 2014 P-value=0.007 Our main finding is an association of FKBP5 polymorphisms (rs1360780, rs9470080, rs4713916, rs9296158 and rs9394309) with major depression but nor with bipolar disorder. Positive