SNP Report

Basic Info

SNP related studies (count: 3)

SNP related genes (count: 2)

Overlap with SZ from cross-disorder studies (count: 2)
Reference |
Statistical Result |
Description |
Result Category |
Bass, N. J.,2009 |
chi-squared tests:for SCZ, allele, X2(1 d.f.)=0.976, P-value = 0.323 |
No significant association was observed. |
Negative |
Papagni, S. A.,2011 |
Diagnosisxgenotype interaction:in the left precuneus (Z-score=4.79, p=0.004 after FWE correction), which also expressed deactivation during generation relative to baseline across different diagnostic and genotypic groups.Exploration of the parameter estimates revealed that, in this region, deactivation during generation relative to baseline was less pronounced in schizophrenic patients with one or two copies of the T allele than those without it (Z-score=4.55, p=0.012 after FWE correction); in contrast the opposite trend was expressed amongst healthy volunteers (Zscore= 2.77, p<0.01 uncorrected)In the right posterior cingulate gyrus (Z-score=4.42, p=0.021 after FWE). In this region, there was activation during generation in patients with schizophrenia who had at least one copy of the T allele while there was deactivation in those without it (Z-score=5.11, p=0.001 after FWE) |
This revealed two regions which expressed a significant diagnosis×genotype interaction at p<0.05 after FEW correction for multiple comparisons. |
Positive |

Overlap with MDD from cross-disorder studies (count: 0)