SNP Report

Basic Info

Name	rs2005976 dbSNP Ensembl
Location	chr6:15650571 - 15650571(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.242812
Functional Annotation	intron_variant; NMD_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000338950, ENST00000344537, ENST00000355917, ENST00000506844, ENST00000510395, ENST00000511762, ENST00000513680, ENST00000515875, ENST00000622898, LRG_588t1, LRG_588t2); NMD_transcript_variant(ENST00000506844, ENST00000510395, ENST00000513680, ENST00000515875)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Breen, G., 2006			P-value < 0.05 under a recessive model P-value < 0.05 under a recessive model	Single nucleotide polymorphism P1757 had p values <0.05 unde...... Single nucleotide polymorphism P1757 had p values <0.05 under a recessive genotypic model for the rare allele. More...	Positive
Pae, C. U., 2007 (a)			COCAPHASE P-value > 0.05 COCAPHASE P-value > 0.05	No significant association was observed in single marker ana...... No significant association was observed in single marker analyses More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
DTNBP1	dystrobrevin binding protein 1	6p22.3	8(4/3/1)

SNPs in LD with rs2005976 (count: 0) View in gBrowse (chr6:15650571..15650571 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)