SNP Report

Basic Info

Name	rs3784406 dbSNP Ensembl
Location	chr15:88142099 - 88142099(1)
Variant Alleles	C/T
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.498003
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000558776); intron_variant(ENST00000317501, ENST00000355254, ENST00000357724, ENST00000360948, ENST00000394480, ENST00000540489, ENST00000542733, ENST00000557856, ENST00000558676, ENST00000559188, ENST00000626019, ENST00000629765)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Athanasiu, L.,2011	T/C		Allelic association: OR=1.255, P-value = 8.12E-02, P-value(t...... Allelic association: OR=1.255, P-value = 8.12E-02, P-value(trend)=8.50E-02 More...	No significant association was observed. No significant association was observed.	Negative
Feng, Y., 2008		A	TDT P-value = 0.025, X²(df=1)=5.013 TDT P-value = 0.025, X²(df=1)=5.013		Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	15q24-q25	2(2/0/0)
MED28P6	mediator complex subunit 28 pseudogene 6	15q25.3	Mapped by Literature SNP

SNPs in LD with rs3784406 (count: 4) View in gBrowse (chr15:88125932..88193744 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs11629691	intron_variant	0.835[CEU]
rs8035239	downstream_gene_variant; intron_variant; upstream_gene_variant	0.812[TSI]
rs1991287	downstream_gene_variant; intron_variant; upstream_gene_variant	0.958[CEU]
rs1426300	intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.882[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)