SNP Report

Basic Info

Name	rs1407598 dbSNP Ensembl
Location	chr1:231811079 - 231811079(1)
Variant Alleles	T/G
Ancestral Allele	T
Minor Allele	G
Minor Allele Frequence	0.266773
Functional Annotation	intron_variant; NMD_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000295051, ENST00000366632, ENST00000366633, ENST00000366636, ENST00000366637, ENST00000422590, ENST00000439617, ENST00000535944, ENST00000535983, ENST00000537876, ENST00000539444, ENST00000602281, ENST00000602567, ENST00000602634, ENST00000602700, ENST00000602713, ENST00000602822, ENST00000602873, ENST00000602885, ENST00000602956, ENST00000602962, ENST00000620189, ENST00000622252, ENST00000628350); NMD_transcript_variant(ENST00000295051, ENST00000366632, ENST00000422590, ENST00000535944, ENST00000602567, ENST00000602634, ENST00000602700, ENST00000602713, ENST00000602822, ENST00000602885, ENST00000602956, ENST00000602962); upstream_gene_variant(ENST00000612827)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Hodgkinson, C. A.,2004			Association analysis: chi square test: genotype P-value = 0....... Association analysis: chi square test: genotype P-value = 0.039, OR=1.133 More...	Significant association was found in BD. Significant association was found in BD.	Positive
Maeda, K., 2006			data not shown data not shown	Analysis of the individual markers identified no significant...... Analysis of the individual markers identified no significant association with BP disorder. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
DISC1	disrupted in schizophrenia 1	1q42.1	18(10/7/1)

SNPs in LD with rs1407598 (count: 0) View in gBrowse (chr1:231811079..231811079 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)