Gene Report

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Basic Info

Approved Symbol	FYTTD1
Symbol Alias	DKFZp761B1514, UIF
Approved Name	forty-two-three domain containing 1
Name Alias	UAP56-interacting factor
Location	3q29
Position	chr3:197737179-197787596, 1
External Links	HGNC: 25407 Entrez Gene: 84248 Ensembl: ENSG00000122068 UCSC: uc003fyi.2
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Schosser, A.,2011	SNP: rs2885470 Haplotype: rs6583248 - rs2885470()	No significant association was observed.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0005654	nucleoplasm	cellular component	IDA	163
GO:0044822	poly(A) RNA binding	molecular function	IDA[22681889]	44
GO:0003729	mRNA binding	molecular function	IDA[19836239]	5
GO:0006406	mRNA export from nucleus	biological process	IMP[19836239]	4
GO:0016607	nuclear speck	cellular component	IDA[19836239]	16
GO:0005515	protein binding	molecular function	IPI[19836239]	563

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Gene	Interactor	Interactor in BDgene?	Experiment Type	PMID
FYTTD1	SHBG	NO	yeast 2-hybrid	15862967
FYTTD1	TSPAN7	NO	yeast 2-hybrid	16169070

Related other genetic factors

Gene related SNPs (count: 6)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs2885470	chr3:197748569 - 197748569(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1(0/1/0)

rs_ID	Location	Functional Annotation
rs3205525	chr3:197768463 - 197768463(1)	3_prime_UTR_variant; missense_variant; NMD_transcript_variant
rs538885	chr3:197792345 - 197792345(1)	downstream_gene_variant; intron_variant; NMD_transcript_variant
rs1398792	chr3:197746739 - 197746739(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs2087605	chr3:197755291 - 197755291(1)	intron_variant; NMD_transcript_variant
rs6787318	chr3:197742767 - 197742767(1)	intron_variant; non_coding_transcript_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 3	chr3:0-198295559	2 (0/2/0)
3q29	chr3:192600000-198295559	2 (1/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr3:197737179..197787596 View in gBrowse