BDgene

SNP Report

Basic Info
Name rs2290035 dbSNP Ensembl
Location chr11:13386224 - 13386224(1)
Variant Alleles T/A
Ancestral Allele T
Minor Allele A
Minor Allele Frequence 0.425719
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript downstream_gene_variant(ENST00000278174, ENST00000527102, ENST00000528120, ENST00000530907); intron_variant(ENST00000389707, ENST00000401424, ENST00000403290, ENST00000403482, ENST00000403510, ENST00000472842, ENST00000524392); NMD_transcript_variant(ENST00000524392); non_coding_transcript_variant(ENST00000472842)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Mansour, H. A., 2006 T/A TDT P-value = 0.181 in the samples combined, Pittsburgh Tren...... TDT P-value = 0.181 in the samples combined, Pittsburgh Trends test=0.09 for BDI More... The loci tested did not show significant differences between...... The loci tested did not show significant differences between sites in the transmission rate. More... Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ARNTL aryl hydrocarbon receptor nuclear translocator-like 11p15 7(5/2/0)
BTBD10 BTB (POZ) domain containing 10 11p15.2 Mapped by Literature SNP

SNPs in LD with rs2290035 (count: 13) View in gBrowse (chr11:13380862..13461680 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 13)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Mansour, H. A., 2006 TDT P-value = 0.935, Trends test=0.689 for Pittsburgh SZ/SZA Negative

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016