SNP Report

Basic Info

Name	rs7769372 dbSNP Ensembl
Location	chr6:37670786 - 37670786(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.267772
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000434837, ENST00000505425, ENST00000515437)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Li, J.,2011(a)	C/T		Single SNP analyses: allele, P-value = 0.5072, OR[95%CI]=0.9...... Single SNP analyses: allele, P-value = 0.5072, OR[95%CI]=0.9586[0.8459, 1.0862], genotype, P-value = 0.7982 for BP More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1	6p21	1(1/0/0)

SNPs in LD with rs7769372 (count: 7) View in gBrowse (chr6:37666398..37673199 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs9296229	intron_variant; upstream_gene_variant	0.944[CHB]; 0.85[JPT]
rs6458008	intron_variant; upstream_gene_variant	0.946[CHB]; 1.0[CHD]; 0.85[JPT]
rs6458009	intron_variant; upstream_gene_variant	1.0[CHB]; 1.0[CHD]; 0.85[JPT]
rs3846883	intron_variant; upstream_gene_variant	0.946[CHB]; 0.85[JPT]
rs9394448	intron_variant	0.804[CHB]
rs6909816	intron_variant; upstream_gene_variant	0.927[CHB]; 0.877[JPT]
rs3846882	intron_variant; upstream_gene_variant	1.0[CHB]; 0.825[JPT]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Li, J.,2011(a)	Single SNP analyses:allele, P-value = 0.9717, OR[95%CI]=1.0023[0.8829, 1.1378], genotype, P-value = 0.5694 for SZ	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Li, J.,2011(a)	Single SNP analyses:allele, P-value = 0.8802, OR[95%CI]=0.9904[0.8732, 1.1232], genotype, P-value = 0.9888 for MDD	No significant association was observed.	Negative