SNP Report

Basic Info

Name	rs495484 dbSNP Ensembl
Location	chr18:10535063 - 10535063(1)
Variant Alleles	T/A
Ancestral Allele	T
Minor Allele	A
Minor Allele Frequence	0.354233
Functional Annotation	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000580746); intron_variant(ENST00000322897, ENST00000580224, ENST00000580483, ENST00000582472, ENST00000582978); NMD_transcript_variant(ENST00000580224, ENST00000580483); non_coding_transcript_variant(ENST00000582978); upstream_gene_variant(ENST00000583367)
No. of Studies	3 (Positive: 1; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 3)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Weller, A. E., 2006	A/T		genotypic P-value = 0.044, allelic P-value = 0.396 genotypic P-value = 0.044, allelic P-value = 0.396	showed a nominal, statistically significant association with...... showed a nominal, statistically significant association with BPD at the genotype frequency level but not at the allele frequency level More...	Positive
Yosifova, A.,2009	A/T		Allelic association: P-value = 0.25 Allelic association: P-value = 0.25	No significant association was observed No significant association was observed	Negative
Li, X.,2009	A/T	A	1.BD patients and control: Allele distribution: Permutated P...... 1.BD patients and control: Allele distribution: Permutated P-value = 0.4761, Genotype distribution: P-value = 0.1451; 2.BD-I patients and control: Allele distribution: Permutated P-value = 0.3773, Genotype distribution: P-value = 0.0456 More...	No significant association was observed in BD group or BD-I ...... No significant association was observed in BD group or BD-I group. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NAPG	N-ethylmaleimide-sensitive factor attachment protein, gamma	18p11.21	3(2/1/0)

SNPs in LD with rs495484 (count: 0) View in gBrowse (chr18:10535063..10535063 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)