SNP Report

Basic Info

Name	rs2072621 dbSNP Ensembl
Location	chrX:151177387 - 151177387(1)
Variant Alleles	C/A
Ancestral Allele	C
Minor Allele	A
Minor Allele Frequence	0.274702
Functional Annotation	intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000218316); non_coding_transcript_exon_variant(ENST00000454196); non_coding_transcript_variant(ENST00000454196); upstream_gene_variant(ENST00000602313)
No. of Studies	2 (Positive: 0; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Thomson, P. A.,2005(b)			Single marker association: for BPAD, allele P-value = 0.61(a...... Single marker association: for BPAD, allele P-value = 0.61(all), P-value = 0.79(male), P-value = 0.71(female); for BPAD+BPspec, allele P-value = 0.42(female) More...	No significant association was observed. No significant association was observed.	Negative
Macintyre, D. J.,2010	A/C		X² goodness of fit test: P-value > 0.05 X² goodness of fit test: P-value > 0.05	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
GPR50-AS1	GPR50 antisense RNA 1	Xq28	Mapped by Literature SNP
GPR50	G protein-coupled receptor 50	Xq28	3(2/1/0)

SNPs in LD with rs2072621 (count: 0) View in gBrowse (chrX:151177387..151177387 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Thomson, P. A.,2005(b)	Single marker association:for SCZ, allele P-value = 0.31(all), P-value = 0.16(male), P-value = 0.0014(female)	Association was not observed in SCZ, but was in observed SCZ(female).	Negative

Overlap with MDD from cross-disorder studies (count: 2)

Reference	Statistical Result	Description	Result Category
Macintyre, D. J.,2010	X² goodness of fit test:P-value > 0.05	No significant association was observed.	Negative
Thomson, P. A.,2005(b)	Single marker association:for MDD, allele P-value = 0.58(all), P-value = 0.19(male), P-value = 0.97(female)	No association was observed.	Negative