Gene Report

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Basic Info

Approved Symbol	IFRD1
Symbol Alias	PC4, TIS7
Approved Name	interferon-related developmental regulator 1
Location	7q31.1
Position	chr7:112422968-112481017, 1
External Links	HGNC: 5456 Entrez Gene: 3475 Ensembl: ENSG00000006652 UCSC: uc003vgh.3
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Chen, X., 2015		IFRD1 has been related to autism.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 4)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0007275	multicellular organismal development	biological process	IEA	24
GO:0005634	nucleus	cellular component	IEA	283

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0007518	myoblast fate determination	biological process	TAS[7756174]	1
GO:0007527	adult somatic muscle development	biological process	IEA	1

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Gene	Interactor	Interactor in BDgene?	Experiment Type	PMID
IFRD1	RIT1	NO	yeast 2-hybrid	16169070
IFRD1	HDAC2	NO	in vitro;in vivo	12198164

Related other genetic factors

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
7q21-31	chr7:77900000-127500000	1 (1/0/0)
Chr 7	chr7:0-159345973	3 (0/3/0)
7q31-33	chr7:107800000-138500000	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

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Region: chr7:112422968..112481017 View in gBrowse