BDgene

SNP Report

Basic Info
Name rs16944 dbSNP Ensembl
Location chr2:112837290 - 112837290(1)
Variant Alleles A/G
Ancestral Allele A
Minor Allele G
Minor Allele Frequence 0.490615
Functional Annotation upstream_gene_variant.
Consequence to Transcript upstream_gene_variant(ENST00000263341, ENST00000416750, ENST00000418817, ENST00000432018, ENST00000477398, ENST00000487639, ENST00000491056, ENST00000496280, ENST00000623243)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Papiol, S.,2004 C/T Association analysis: chi square test, Bipolar disorder v co...... Association analysis: chi square test, Bipolar disorder v controls: allele: chi square= 1.48, P-value = 0.223; OR = 1.27 (95% CI: 0.85 to 1.90); genotype: chi square= 2.89; P-value = 0.235.Bipolar disorder FH+ v controls: allele: chi square=1.58, P-value = 0.208; OR=1.33 (95% CI: 0.84 to 2.14); genotype: chi square=1.79; P-value = 0.408. More... No significant association was observed in BD. No significant association was observed in BD. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
IL1B interleukin 1, beta 2q14 1(1/0/0)

SNPs in LD with rs16944 (count: 0) View in gBrowse (chr2:112837290..112837290 )

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Papiol, S.,2004 Association analysis:chi square test, Schizophrenia v controls: allele: chi square= 3.79, P-value = 0.051; OR = 1.50 (95% CI: 0.98 to 2.31); genotype: chi square= 4.26, P-value = 0.119. No significant association was observed in SZ. Negative

Overlap with MDD from cross-disorder studies (count: 0)