SNP Report

Basic Info

Name	rs16944 dbSNP Ensembl
Location	chr2:112837290 - 112837290(1)
Variant Alleles	A/G
Ancestral Allele	A
Minor Allele	G
Minor Allele Frequence	0.490615
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000263341, ENST00000416750, ENST00000418817, ENST00000432018, ENST00000477398, ENST00000487639, ENST00000491056, ENST00000496280, ENST00000623243)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Papiol, S.,2004	C/T		Association analysis: chi square test, Bipolar disorder v co...... Association analysis: chi square test, Bipolar disorder v controls: allele: chi square= 1.48, P-value = 0.223; OR = 1.27 (95% CI: 0.85 to 1.90); genotype: chi square= 2.89; P-value = 0.235.Bipolar disorder FH+ v controls: allele: chi square=1.58, P-value = 0.208; OR=1.33 (95% CI: 0.84 to 2.14); genotype: chi square=1.79; P-value = 0.408. More...	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
IL1B	interleukin 1, beta	2q14	1(1/0/0)

SNPs in LD with rs16944 (count: 0) View in gBrowse (chr2:112837290..112837290 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Papiol, S.,2004	Association analysis:chi square test, Schizophrenia v controls: allele: chi square= 3.79, P-value = 0.051; OR = 1.50 (95% CI: 0.98 to 2.31); genotype: chi square= 4.26, P-value = 0.119.	No significant association was observed in SZ.	Negative

Overlap with MDD from cross-disorder studies (count: 0)