SNP Report
Basic Info
Name |
rs909669
dbSNP
Ensembl
|
Location |
chr22:40346413 - 40346413(1) |
Variant Alleles |
C/T |
Ancestral Allele |
C |
Minor Allele |
T |
Minor Allele Frequence |
0.209465 |
Functional Annotation |
upstream_gene_variant.
|
Consequence to Transcript |
upstream_gene_variant(ENST00000216194, ENST00000342312, ENST00000466863, ENST00000477111, ENST00000623063, ENST00000623287, ENST00000623632, ENST00000623978, ENST00000624474, ENST00000624503, ENST00000636124, ENST00000636265, ENST00000636714, ENST00000637666, ENST00000637669, ENST00000638161) |
No. of Studies |
2 (Positive: 1; Negative: 1; Trend: 0) |
Source |
Literature |
Overlap with SZ? |
YES
|
Overlap with MDD? |
NO
|
SNP related studies (count: 2)
SNP related genes (count: 1)
Overlap with SZ from cross-disorder studies (count: 1)
Reference |
Statistical Result |
Description |
Result Category |
Severinsen, J. E., 2006 (a) |
CLUMP T1 P-value = 0.1178, CLUMP T4 P-value = 0.1178 for SZ; CLUMP T1 P-value = 0.0036, CLUMP T4 P-value = 0.0036 for BPD and SZ in the Faeroese Sample; Empirical overall P-value = 0.0655 for SZ in the Case-Control Sample From Scotland; Empirical overall P-value = 0.2189 for BPD and SZ in the Case-Control Sample From Scotland |
In BPD and BPD/SZ combined, single marker association was observed for rs909669 (ADSL) and rs133070 (GPR24) with P-values between 0.0036 and 0.037. |
Positive |
Overlap with MDD from cross-disorder studies (count: 0)