BDgene

BD & SZ shared SNPs from cross-disorder studies

Total result: 838

SNP Related Gene(s) No. of Studies (Positive/Trend/Negative) for BD No. of Studies for SZ Overlap with SZ
Statistical Results Description Result Category Reference
rs2391191 DAOA DAOA-AS1 18(3/0/15) 7
Association analysis:allele P-value = 0.037, OR=1.28, genot...... Association analysis:allele P-value = 0.037, OR=1.28, genotype P-value = 0.108, OR=1.41 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Schumacher, J.,2004
Meta analysis:Fixed-effects model:ORA = 1.03, 95% CI: 1.00-...... Meta analysis:Fixed-effects model:ORA = 1.03, 95% CI: 1.00-1.07, p = 0.07;Random-effects model: ORA = 1.05, 95% CI:0.97-1.13, p = 0.22.But in the East Asian subgroup (p = 0.02). More... Significant association was observed in the East Asian subg...... Significant association was observed in the East Asian subgroup. More... Positive Muller, D. J.,2011
rs6265 BDNF BDNF-AS 17(7/0/10) 3
allele:X2=7.89, P-value = 0.0049, OR=1.48, upper...... allele:X2=7.89, P-value = 0.0049, OR=1.48, upper 95%CI=1.95, lower CI=1.13;genotype:X2=10.1; P-value = 0.0015; OR=1.68; upper 95% CI=1.22, lower 95% CI=2.32. More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Neves-Pereira, M.,2005
P-value = 0.944, OR=1.00 (95% CI: 0.89-1.11), z=0.07, heter...... P-value = 0.944, OR=1.00 (95% CI: 0.89-1.11), z=0.07, heterogeneity P-value = 0.078, X2=19.47 (d.f.=12) for schizophrenia More... The meta-analysis of data showed no support for an associat...... The meta-analysis of data showed no support for an association with the putative risk allele (Met). Some evidence of heterogeneity was observed among the studies, but this did not attain statistical significance. More... Negative Kanazawa, T., 2007
rs1006737 CACNA1C 15(9/2/4) 4
Conditional FDR; SCZ loci given BD: P-value=0.0000352, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000352, FDR=0.104, FDR=0.022 for SCZ and BD||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.022 for BD and SZ, Z-score=4.137 for SZ More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.61. This SNP is with conjunction FDR<0.13 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
genotype test P-value = 0.034 when using Controls (WTCCC) a...... genotype test P-value = 0.034 when using Controls (WTCCC) as control, genotype test P-value = 0.043 when using WTCCC expanded reference as control, OR(%95 CI) =1.15 (0.99-1.32) for allele test when using Controls (WTCCC) as control, OR(%95 CI)=1.13 (0.98-1.29) for allele test when using WTCCC expanded reference as control; More... We found that the risk allele conferred increased risk for ...... We found that the risk allele conferred increased risk for schizophrenia (P= 0.034) with similar effect sizes to those previously observed in BD (allelic odds ratio B1.15). More... Positive Green, E. K., 2010
rs1935062 DAOA DAOA-AS1 12(6/0/6) 2
Association analysis:allele P-value = 0.494, OR=1.09, genot...... Association analysis:allele P-value = 0.494, OR=1.09, genotype P-value = 0.45, OR=1.21 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Schumacher, J.,2004
Fisher P-value = 0.0143 for all, P-value = 0.9804 for SCZ O...... Fisher P-value = 0.0143 for all, P-value = 0.9804 for SCZ Only More... When results are combined across studies and phenotypes, th...... When results are combined across studies and phenotypes, this marker showed significant combined p value. Combined results in schizophrenia are significant for several markers. More... Positive Detera-Wadleigh, S. D., 2006
rs10994336 ANK3 12(7/0/5) 4
Genotype association:CC P-value = 0.617, CT P-value = 0.689...... Genotype association:CC P-value = 0.617, CT P-value = 0.689, TT P-value = 0.62 for SZ. More... No significant association was observed. No significant association was observed. Negative Gella, A.,2011
All ethnicities: OR=0.98, 95%CI =0.78-1.23, P-value=0.840; ...... All ethnicities: OR=0.98, 95%CI =0.78-1.23, P-value=0.840; Malay: OR=0.62, 95%CI =0.40-0.95, P-value=0.029; Chinese: OR=1.05, 95%CI =0.76-1.46, P-value=0.776; Indian: OR=1.45, 95%CI =0.91-2.32, P-value=0.116 More... rs10994336 was significantly different between BPD and SZ p...... rs10994336 was significantly different between BPD and SZ patients and controls of Malay ethnicity(P= 0.001 and 0.012, for BPD and SZ, respectively). More... Positive Lim C.H., 2014
rs3918342 DAOA 11(4/0/7) 3
Fisher P-value = 0 for all, P-value = 0.0006 for SCZ Only Fisher P-value = 0 for all, P-value = 0.0006 for SCZ Only When results are combined across studies and phenotypes, th...... When results are combined across studies and phenotypes, this marker showed significant combined p value. Combined results in schizophrenia are significant for several markers and are highly significant (p<0.001) for three markers spanning more than 82 kb. More... Positive Detera-Wadleigh, S. D., 2006
chi-squared tests:for SCZ, allele, X2(1 d.f.)=5....... chi-squared tests:for SCZ, allele, X2(1 d.f.)=5.824, P-value = 0.016 More... Significant association was observed in allelic association...... Significant association was observed in allelic association in SCZ. More... Positive Bass, N. J.,2009
rs778294 DAOA DAOA-AS1 10(3/0/7) 5
Association analysis:allele P-value = 0.27, OR=1.15, genoty...... Association analysis:allele P-value = 0.27, OR=1.15, genotype P-value = 0.504, OR=1.21 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Schumacher, J.,2004
chi-squared tests:for SCZ, allele, X2(1 d.f.)=0....... chi-squared tests:for SCZ, allele, X2(1 d.f.)=0.141, P-value = 0.707 More... No significant association was observed. No significant association was observed. Negative Bass, N. J.,2009
rs1341402 DAOA DAOA-AS1 10(3/0/7) 3
allelic P-value = 0.82 in Schizophrenia allelic P-value = 0.82 in Schizophrenia We found no evidence for allelic or genotypic association w...... We found no evidence for allelic or genotypic association with any of the polymorphisms studied for schizophrenia. We observed nominally significant evidence (P=.01-.047) for allelic association with 3 of the polymorphisms for bipolar disorder and significant evidence for whole-gene association (P=.04). More... Negative Williams, N. M., 2006
Association analysis:allele P-value = 0.352, OR=1.14, genot...... Association analysis:allele P-value = 0.352, OR=1.14, genotype P-value = 0.55, OR=1.48 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Schumacher, J.,2004
rs947267 DAOA DAOA-AS1 9(1/0/8) 3
chi-squared tests:for SCZ, allele, X2(1 d.f.)=0....... chi-squared tests:for SCZ, allele, X2(1 d.f.)=0.203, P-value = 0.652 More... No significant association was observed. No significant association was observed. Negative Bass, N. J.,2009
Fisher P-value = 0.2256 for all, P-value = 0.9478 for SCZ O...... Fisher P-value = 0.2256 for all, P-value = 0.9478 for SCZ Only More... Negative Detera-Wadleigh, S. D., 2006
rs1421292 DAOA 8(2/0/6) 3
allelic P-value = 0.66 in Schizophrenia allelic P-value = 0.66 in Schizophrenia We found no evidence for allelic or genotypic association w...... We found no evidence for allelic or genotypic association with any of the polymorphisms studied for schizophrenia. We observed nominally significant evidence (P=.01-.047) for allelic association with 3 of the polymorphisms for bipolar disorder and significant evidence for whole-gene association (P=.04). More... Negative Williams, N. M., 2006
Fisher P-value = 0.001 for all, P-value = 0.0092 for SCZ On...... Fisher P-value = 0.001 for all, P-value = 0.0092 for SCZ Only More... When results are combined across studies and phenotypes, th...... When results are combined across studies and phenotypes, this marker showed significant combined p value. Combined results in schizophrenia are significant for several markers. More... Positive Detera-Wadleigh, S. D., 2006
rs1170191 DGKH 7(1/0/6) 1
Allelic association:P-value = 0.052, permutated P-value = 0...... Allelic association:P-value = 0.052, permutated P-value = 0.385 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs1935058 DAOA-AS1 DAOA 7(3/0/4) 2
allelic P-value = 0.52 in Schizophrenia allelic P-value = 0.52 in Schizophrenia We found no evidence for allelic or genotypic association w...... We found no evidence for allelic or genotypic association with any of the polymorphisms studied for schizophrenia. We observed nominally significant evidence (P=.01-.047) for allelic association with 3 of the polymorphisms for bipolar disorder and significant evidence for whole-gene association (P=.04). More... Negative Williams, N. M., 2006
Fisher P-value = 0.0015 for all, P-value = 0.4416 for SCZ O...... Fisher P-value = 0.0015 for all, P-value = 0.4416 for SCZ Only More... When results are combined across studies and phenotypes, th...... When results are combined across studies and phenotypes, this marker showed significant combined p value. Combined results in schizophrenia are significant for several markers. More... Positive Detera-Wadleigh, S. D., 2006
rs954581 DAOA-AS1 DAOA 7(0/0/7) 2
Fisher P-value = 0.5966 for all, P-value = 1 for SCZ Only Fisher P-value = 0.5966 for all, P-value = 1 for SCZ Only Negative Detera-Wadleigh, S. D., 2006
allelic P-value = 0.67 in Schizophrenia allelic P-value = 0.67 in Schizophrenia We found no evidence for allelic or genotypic association w...... We found no evidence for allelic or genotypic association with any of the polymorphisms studied for schizophrenia. We observed nominally significant evidence (P=.01-.047) for allelic association with 3 of the polymorphisms for bipolar disorder and significant evidence for whole-gene association (P=.04). More... Negative Williams, N. M., 2006
rs165599 ARVCF COMT 7(5/0/2) 2
OR (95% CI)=1.13 (0.99-1.30) of males, OR (95% CI)=1.47 (1....... OR (95% CI)=1.13 (0.99-1.30) of males, OR (95% CI)=1.47 (1.22-1.77) of females More... previously found to be associated with schizophrenia previously found to be associated with schizophrenia Positive Shifman, S., 2004
Allelic association:for SCZ, P-value = 0.221, trend P-value...... Allelic association:for SCZ, P-value = 0.221, trend P-value = 0.24, OR (95%CI)=1.17(0.91, 1.51);for SCZ+SA, P-value = 0.16, trend P-value = 0.175, OR (95%CI)=1.18(0.94, 1.49) More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Funke, B.,2005
rs9834970 TRANK1 LRBA 6(3/2/1) 2
P-value=7.18E-05 for BP, P-value=5.53E-13 for BP+SZ, Het P-...... P-value=7.18E-05 for BP, P-value=5.53E-13 for BP+SZ, Het P-value=0.85 More... Most significant SNP in six genome-wide significant regions...... Most significant SNP in six genome-wide significant regions. More... Negative Ruderfer, D. M., 2013
Conditional FDR; BD loci given SCZ: FDR=0.02711 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.02711 for BD and SCZ||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.027 for BD and SZ, Z-score=3.965 for SZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. This SNP is with conjunction FDR<0.08 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs3916965 DAOA 6(2/0/4) 2
Fisher P-value = 0.0001 for all, P-value = 0.0002 for SCZ O...... Fisher P-value = 0.0001 for all, P-value = 0.0002 for SCZ Only More... When results are combined across studies and phenotypes, th...... When results are combined across studies and phenotypes, this marker showed significant combined p value. Combined results in schizophrenia are significant for several markers and are highly significant (p<0.001) for three markers spanning more than 82 kb. More... Positive Detera-Wadleigh, S. D., 2006
chi-squared tests:for SCZ, allele, X2(1 d.f.)=2....... chi-squared tests:for SCZ, allele, X2(1 d.f.)=2.101, P-value = 0.147 More... No significant association was observed. No significant association was observed. Negative Bass, N. J.,2009
rs9804190 ANK3 6(2/0/4) 2
Genotype association:CC P-value = 0.949, CT P-value = 0.674...... Genotype association:CC P-value = 0.949, CT P-value = 0.674, TT P-value = 0.284 for SZ. More... No significant association was observed. No significant association was observed. Negative Gella, A.,2011
SCOPE sample:MAF=0.21, Cochrane-Mantel-Haenszel test P-valu...... SCOPE sample:MAF=0.21, Cochrane-Mantel-Haenszel test P-value = 0.88, Bonferroni corrected P-value = 1, OR (95%CI)=0.99(0.87-1.13);Icelandic sample:MAF(affected)=0.23, MAF(unaffected)=0.22, allelic P-value = 0.5, Bonferroni corrected P-value = 1, OR (95%CI)=1.05(0.92-1.20) More... No significant association was observed. No significant association was observed. Negative Tesli, M.,2011
rs778293 DAOA 6(2/0/4) 3
chi-squared tests:for SCZ, allele, X2(1 d.f.)=0....... chi-squared tests:for SCZ, allele, X2(1 d.f.)=0.93, P-value = 0.335 More... No significant association was observed. No significant association was observed. Negative Bass, N. J.,2009
allelic P-value = 0.44 in Schizophrenia allelic P-value = 0.44 in Schizophrenia We found no evidence for allelic or genotypic association w...... We found no evidence for allelic or genotypic association with any of the polymorphisms studied for schizophrenia. We observed nominally significant evidence (P=.01-.047) for allelic association with 3 of the polymorphisms for bipolar disorder and significant evidence for whole-gene association (P=.04). More... Negative Williams, N. M., 2006
rs1012053 DGKH 6(1/0/5) 1
Allelic association:P-value = 0.074, permutated P-value = 0...... Allelic association:P-value = 0.074, permutated P-value = 0.494 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs1801260 CLOCK TMEM165 6(3/0/3) 1
chi-square test: 1. total samples:P-value = 0.321(Genotype)...... chi-square test: 1. total samples:P-value = 0.321(Genotype), P-value = 0.519(Allele) in SCZ 2. male samples: P-value = 0.856(Genotype), P-value = 0.680(Allele) in SCZ 3. female samples: P-value = 0.196(Genotype), P-value = 0.105(Allele) in SCZ More... We did not find an association between these tag SNPs and J...... We did not find an association between these tag SNPs and Japanese schizophrenia, BP or MDD in any of the analyses. More... Negative Kishi, T.,2009(a)
rs821616 DISC1 TSNAX 6(1/0/5) 3
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.5 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
SZ patients: P-value=0.179, P-value=0.213 for females, P-va...... SZ patients: P-value=0.179, P-value=0.213 for females, P-value=0.579 for males; BPAD&SCZ: P-value=0.04, P-value=0.138 for females, P-value=0.183 for males More... One SNP (rs821616) showed moderate significant association ...... One SNP (rs821616) showed moderate significant association with cases compared with controls in regression analysis More... Positive Ram Murthy, A., 2012
rs9315885 DGKH MAPK6PS3 6(0/0/6) 1
Allelic association:P-value = 0.014, permutated P-value = 0...... Allelic association:P-value = 0.014, permutated P-value = 0.127 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs4680 COMT 6(3/0/3) 2
OR (95% CI)=1.14 (0.99-1.32) of males, OR (95% CI)=1.09 (0....... OR (95% CI)=1.14 (0.99-1.32) of males, OR (95% CI)=1.09 (0.90-1.32) of females More... previously found to be associated with schizophrenia previously found to be associated with schizophrenia Positive Shifman, S., 2004
Allelic association:for SCZ, P-value = 0.419, trend P-value...... Allelic association:for SCZ, P-value = 0.419, trend P-value = 0.414, OR (95%CI)=1.1(0.87, 1.41);for SCZ+SA, P-value = 0.304, trend P-value = 0.299, OR (95%CI)=1.12(0.90, 1.40) More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Funke, B.,2005
rs3738401 DISC1 TSNAX 5(0/0/5) 2
SZ patients: P-value=0.794, P-value=0.473 for females, P-va...... SZ patients: P-value=0.794, P-value=0.473 for females, P-value=0.427 for males; BPAD&SCZ: P-value=0.520, P-value=0.875 for females, P-value=0.529 for males More... Negative Ram Murthy, A., 2012
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.15 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs1344706 ZNF804A 5(3/0/2) 3
P-value<0.00001, I2=71%, chi-square=100.88 df=29...... P-value<0.00001, I2=71%, chi-square=100.88 df=29, Heterrogeneity Tau2=0.01 More... In the subgroup analysis of diseases, we found a significan...... In the subgroup analysis of diseases, we found a significant associationbetween the T-allele of rs1344706 and schizophrenia in the random effect meta-analysis More... Positive Sun, Y., 2015
X2 tests:allele P-value = 0.31 for SCZ. X2 tests:allele P-value = 0.31 for SCZ. No significant association was observed. No significant association was observed. Negative Schanze, D.,2011
rs737865 COMT TXNRD2 5(2/0/3) 2
OR (95% CI)=1.19 (1.03-1.37) of males, OR (95% CI)=1.27 (1....... OR (95% CI)=1.19 (1.03-1.37) of males, OR (95% CI)=1.27 (1.04-1.54) of females More... previously found to be associated with schizophrenia previously found to be associated with schizophrenia Positive Shifman, S., 2004
Allelic association:for SCZ, P-value = 0.511, trend P-value...... Allelic association:for SCZ, P-value = 0.511, trend P-value = 0.518, OR (95%CI)=1.09(0.84, 1.41);for SCZ+SA, P-value = 0.438, trend P-value = 0.448, OR (95%CI)=1.1(0.87, 1.39) More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Funke, B.,2005
rs6746896 LMAN2L CNNM4 5(3/2/0) 1
All ethnicities: OR=1.34, 95%CI =1.12-1.61, P-value=0.001; ...... All ethnicities: OR=1.34, 95%CI =1.12-1.61, P-value=0.001; Malay: OR=1.50, 95%CI =1.07-2.10, P-value=0.020; Chinese: OR=1.21, 95%CI =0.94-1.55, P-value=0.148; Indian: OR=1.59, 95%CI =0.98-2.58, P-value=0.061 More... rs6746896 shows significant differences in allelic distribu...... rs6746896 shows significant differences in allelic distribution between both BPD and SZ patients and controls for the pooled subjects (P =0.009 and 0.001, respectively). More... Positive Lim C.H., 2014
rs420259 PALB2 5(3/0/2) 1
CMH test:P-value = 0.54, OR (95% CI)=1.04(0.91-1.20) for SC...... CMH test:P-value = 0.54, OR (95% CI)=1.04(0.91-1.20) for SCZ. More... No significant association was observed. No significant association was observed. Negative Tesli, M.,2010
rs2251219 PBRM1 SMIM4 RNU6-856P 5(5/0/0) 2
Association analysis:allele P-value = 0.21, OR=0.97 Association analysis:allele P-value = 0.21, OR=0.97 No significant association was observed in SZ. No significant association was observed in SZ. Negative Vassos, E.,2012
P-value = 0.0018,OR= 1.21;P-value = 0.0051,P-vorrection = 0...... P-value = 0.0018,OR= 1.21;P-value = 0.0051,P-vorrection = 0.01,OR = 1.13 for replication. More... Significant association was observed. Significant association was observed. Positive Kondo, K.,2013
rs1938526 ANK3 5(3/0/2) 2
All ethnicities: OR=0.86, 95%CI =0.71-1.04, P-value=0.123; ...... All ethnicities: OR=0.86, 95%CI =0.71-1.04, P-value=0.123; Malay: OR=0.60, 95%CI =0.41-0.89, P-value=0.012; Chinese: OR=0.87, 95%CI =0.66-1.15, P-value=0.334; Indian: OR=1.21, 95%CI =0.79-1.83, P-value=0.384 More... rs1938526 was found to be significantly associated with BPD...... rs1938526 was found to be significantly associated with BPD and SZ. More... Positive Lim C.H., 2014
SCOPE sample:MAF=0.073, Cochrane-Mantel-Haenszel test P-val...... SCOPE sample:MAF=0.073, Cochrane-Mantel-Haenszel test P-value = 0.95, Bonferroni corrected P-value = 1, OR (95%CI)=0.99(0.81-1.22);Icelandic sample:MAF(affected)=0.06, MAF(unaffected)=0.058, allelic P-value = 0.32, Bonferroni corrected P-value = 0.96, OR (95%CI)=1.03(0.81-1.31) More... No significant association was observed. No significant association was observed. Negative Tesli, M.,2011
rs9371601 SYNE1 5(4/1/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.02196 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.02196 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs766288 TSNAX DISC1 4(1/0/3) 2
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.72 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
SZ patients: P-value=0.906, P-value=0.03 for females, P-val...... SZ patients: P-value=0.906, P-value=0.03 for females, P-value=0.105 for males; BPAD&SCZ: P-value=0.336, P-value=0.004 for females, P-value=0.248 for males More... The most significant association was found for combined fem...... The most significant association was found for combined female cases of BPAD or SCZ. Moderate associations were also observed in females for rs766288 (SCZ, P=0.03) More... Positive Ram Murthy, A., 2012
rs1000731 DISC1 TSNAX 4(0/0/4) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.96 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs6313 HTR2A 4(0/0/4) 1
Overall: T vs. C (Allele frequency): OR=0.970, 95%CI=0.914-...... Overall: T vs. C (Allele frequency): OR=0.970, 95%CI=0.914-1.030, P-value=0.316; TT + TC vs. CC (Dominant): OR=0.970, 95%CI=0.888-1.059, P-value=0.495; TT vs. TC + CC (Recessive): OR=0.965, 95%CI=0.885-1.053, P-value=0.428; TT vs. TC (Codominant1): OR=0.982, 95%CI=0.921-1.047, P-value=0.578; TC vs. CC (Codominant2): OR=1.010, 95%CI=0.949-1.074, P-value=0.761; TT vs. CC (Homozygote): OR=0.948, 95%CI=0.838-1.073, P-value=0.397. Caucasian: T vs. C (Allele frequency): OR=0.994, 95%CI=0.903-1.093, P-value=0.894; TT + TC vs. CC (Dominant): OR=0.989, 95%CI=0.887-1.102, P-value=0.84; TT vs. TC + CC (Recessive): OR=0.989, 95%CI=0.838-1.167, P-value=0.895; TT vs. TC (Codominant1): OR=1.011, 95%CI=0.919-1.112, P-value=0.824; TC vs. CC (Codominant2): OR=1.018, 95%CI=0.940-1.102, P-value=0.664; TT vs. CC (Homozygote): OR=0.968, 95%CI=0.796-1.178, P-value=0.747. Asian: T vs. C (Allele frequency): OR=0.952, 95%CI=0.879-1.032, P-value=0.232; TT + TC vs. CC (Dominant): OR=0.956, 95%CI=0.822-1.113, P-value=0.564; TT vs. TC + CC (Recessive): OR=0.949, 95%CI=0.867-1.040, P-value=0.265; TT vs. TC (Codominant1): OR=0.951, 95%CI=0.870-1.038, P-value=0.261; TC vs. CC (Codominant2): OR=1.016, 95%CI=0.917-1.126, P-value=0.761; TT vs. CC (Homozygote): OR=0.933, 95%CI=0.786-1.106, P-value=0.423. Other/Mixed: T vs. C (Allele frequency): OR=0.929, 95%CI=0.742-1.164, P-value=0.523; TT + TC vs. CC (Dominant): OR=0.834, 95%CI=0.521-1.333, P-value=0.447; TT vs. TC + CC (Recessive): OR=1.034, 95%CI=0.719-1.486, P-value=0.856; TT vs. TC (Codominant1): OR=1.142, 95%CI=0.772-1.69, P-value=0.505; TC vs. CC (Codominant2): OR=0.769, 95%CI=0.525-1.128, P-value=0.179; TT vs. CC (Homozygote): OR=0.882, 95%CI=0.572-1.360, P-value=0.57. Chinese: T vs. C (Allele frequency): OR=0.990, 95%CI=0.925-1.059, P-value=0.77; TT + TC vs. CC (Dominant): OR=1.017, 95%CI=0.899-1.150, P-value=0.793; TT vs. TC + CC (Recessive): OR=0.967, 95%CI=0.875-1.069, P-value=0.516; TT vs. TC (Codominant1): OR=0.957, 95%CI=0.861-1.064, P-value=0.419; TC vs. CC (Codominant2): OR=1.032, 95%CI=0.905-1.176, P-value=0.64; TT vs. CC (Homozygote): OR=1.004, 95%CI=0.872-1.154, P-value=0.961 More... The results of our study indicate that theT102C polymorphis...... The results of our study indicate that theT102C polymorphism is not associates with increased susceptibility to SCZ. More... Negative Tan J., 2014
rs3916967 DAOA DAOA-AS1 4(2/0/2) 2
Fisher P-value = 0.0734 for all, P-value = 0.0734 for SCZ O...... Fisher P-value = 0.0734 for all, P-value = 0.0734 for SCZ Only More... Negative Detera-Wadleigh, S. D., 2006
chi-squared tests:for SCZ, allele, X2(1 d.f.)=3....... chi-squared tests:for SCZ, allele, X2(1 d.f.)=3.675, P-value = 0.055 More... No significant association was observed. No significant association was observed. Negative Bass, N. J.,2009
rs6675281 DISC1 TSNAX 4(0/0/4) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.57 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs3916966 DAOA-AS1 DAOA 4(1/0/3) 1
Fisher P-value = 0.0413 for all, P-value = 0.0683 for SCZ O...... Fisher P-value = 0.0413 for all, P-value = 0.0683 for SCZ Only More... When results are combined across studies and phenotypes, th...... When results are combined across studies and phenotypes, this marker showed significant combined p value. Combined results in schizophrenia are significant for several markers. More... Positive Detera-Wadleigh, S. D., 2006
rs8192625 TAAR6 4(1/0/3) 1
Allele frequency (SZ vs.control) 0.02 vs. 0.01; P-value > ...... Allele frequency (SZ vs.control) 0.02 vs. 0.01; P-value > 0.05 More... Negative Pae, C. U., 2008
rs1538977 DISC1 TSNAX 4(0/0/4) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.98 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs7296288 DHH 4(3/1/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.02777 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.02777 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs2919390 NRG1 3(2/0/1) 2
X2 test:P-value = 0.01 for Scottish 1, P-value =...... X2 test:P-value = 0.01 for Scottish 1, P-value = 0.92 for German More... Significant association was found. Significant association was found. Positive Walker, R. M.,2010
Individual P-value = 0.0096 for SCZ , Individual P-value = ...... Individual P-value = 0.0096 for SCZ , Individual P-value = 0.0105 for SCZ and BP More... This marker is nominally significant in the combined sample This marker is nominally significant in the combined sample Positive Thomson, P. A., 2007
rs2812393 DISC1 TSNAX 3(1/0/2) 2
SZ patients: P-value=0.093, P-value=0.026 for females, P-va...... SZ patients: P-value=0.093, P-value=0.026 for females, P-value=0.775 for males; BPAD&SCZ: P-value=0.073, P-value=0.028 for females, P-value=0.668 for males More... Moderate associations were also observed in females for rs2...... Moderate associations were also observed in females for rs2812393 (SCZ, P=0.026; BPAD&SCZ, P=0.028). More... Positive Ram Murthy, A., 2012
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.6 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs1982350 ARNTL 3(2/0/1) 1
TDT P-value = 0.561, Trends test=0.255 for Pittsburgh SZ/SZ...... TDT P-value = 0.561, Trends test=0.255 for Pittsburgh SZ/SZA; case-control P-value = 0.028, X2=7.137, df=2 when contrasting genotype distributions More... Contrasting genotype distributions in cases with the popula...... Contrasting genotype distributions in cases with the population-based sample did not reveal any significant differences by the trend test, although the genotype distribution for ARNTL rs1982350 was noted to be significantly different. More... Positive Mansour, H. A., 2006
rs1630250 TSNAX DISC1 3(0/0/3) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.95 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs3918346 DAO DAOA 3(0/0/3) 2
chi-squared tests:for SCZ, allele, X2(1 d.f.)=0....... chi-squared tests:for SCZ, allele, X2(1 d.f.)=0.976, P-value = 0.323 More... No significant association was observed. No significant association was observed. Negative Bass, N. J.,2009
Diagnosisxgenotype interaction:in the left precuneus (Z-sco...... Diagnosisxgenotype interaction:in the left precuneus (Z-score=4.79, p=0.004 after FWE correction), which also expressed deactivation during generation relative to baseline across different diagnostic and genotypic groups.Exploration of the parameter estimates revealed that, in this region, deactivation during generation relative to baseline was less pronounced in schizophrenic patients with one or two copies of the T allele than those without it (Z-score=4.55, p=0.012 after FWE correction); in contrast the opposite trend was expressed amongst healthy volunteers (Zscore= 2.77, p<0.01 uncorrected)In the right posterior cingulate gyrus (Z-score=4.42, p=0.021 after FWE). In this region, there was activation during generation in patients with schizophrenia who had at least one copy of the T allele while there was deactivation in those without it (Z-score=5.11, p=0.001 after FWE) More... This revealed two regions which expressed a significant dia...... This revealed two regions which expressed a significant diagnosis×genotype interaction at p<0.05 after FEW correction for multiple comparisons. More... Positive Papagni, S. A.,2011
rs228729 VAMP3 PER3 3(0/0/3) 1
TDT P-value = 0.914, Trends test=0.028 for Pittsburgh SZ/SZ...... TDT P-value = 0.914, Trends test=0.028 for Pittsburgh SZ/SZA More... Negative Mansour, H. A., 2006
rs11191580 NT5C2 3(3/0/0) 2
Association analysis:OR=1.19, P-value = 0.01 Association analysis:OR=1.19, P-value = 0.01 Significant association was observed in SZ. Significant association was observed in SZ. Positive association was observed in SZ. Hamshere, M. L.,2012
Conditional FDR; SCZ loci given BD: P-value=0.00000171, FDR...... Conditional FDR; SCZ loci given BD: P-value=0.00000171, FDR=0.049, FDR=0.005 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs2295814 EGR2 ADO 3(1/0/2) 1
For SZ, chi-square tests:allele, OR=1.451, X2=3....... For SZ, chi-square tests:allele, OR=1.451, X2=3.1172, P-value = 0.0775, P-value(permutation)=0.3337;Fisher's exact test, genotype, X2=3.2943, P-value = 0.1926 More... No significant association was observed. No significant association was observed. Negative Kim, S. H.,2011
rs1322784 DISC1 TSNAX 3(0/0/3) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.56 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs2535629 ITIH3 3(3/0/0) 2
Association analysis:P-value = 0.00000000000254,OR(95%CI) =...... Association analysis:P-value = 0.00000000000254,OR(95%CI) = 1.1(1.07–1.12) when five disorders were combined More... Significant association was observed in cross-disorder anal...... Significant association was observed in cross-disorder analysis. More... Positive Cross-Disorder Group of the Psychiatric Genomics Consortium,2013
Conditional FDR; BD loci given SCZ: FDR=0.00279 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.00279 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs4332037 MAD1L1 3(1/1/1) 1
Conditional FDR; BD loci given SCZ: FDR=0.02918 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.02918 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs6937506 TAAR6 3(0/0/3) 1
Allele frequency (SZ vs.control) 0.18 vs. 0.15; P-value > ...... Allele frequency (SZ vs.control) 0.18 vs. 0.15; P-value > 0.05 More... Negative Pae, C. U., 2008
rs2492367 DISC1 TSNAX 3(1/0/2) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.5 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs2271893 LMAN2L 3(2/0/1) 2
All ethnicities: OR=1.24, 95%CI =0.99-1.56, P-value=0.060; ...... All ethnicities: OR=1.24, 95%CI =0.99-1.56, P-value=0.060; Malay: OR=2.63, 95%CI =1.40-4.97, P-value=0.003; Chinese: OR=0.86, 95%CI =0.64-1.15, P-value=0.297; Indian: OR=2.76, 95%CI =1.46-5.20, P-value=0.002 More... rs2271893 C allele frequency was significantly higher in SZ...... rs2271893 C allele frequency was significantly higher in SZ patients compared with healthy controls, a condition observed in Malays and Indians (P= 0.002 and P= 0.003, respectively). More... Positive Lim C.H., 2014
Conditional FDR; BD loci given SCZ: FDR=0.0096 for BD and S...... Conditional FDR; BD loci given SCZ: FDR=0.0096 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs3741775 DAO DAOA 3(0/0/3) 1
chi-squared tests:for SCZ, allele, X2(1 d.f.)=0....... chi-squared tests:for SCZ, allele, X2(1 d.f.)=0.587, P-value = 0.444 More... No significant association was observed. No significant association was observed. Negative Bass, N. J.,2009
rs2297488 EGR2 3(1/0/2) 1
For SZ, chi-square tests:allele, OR=1.114, X2=0....... For SZ, chi-square tests:allele, OR=1.114, X2=0.3127, P-value = 0.576, P-value(permutation)=0.5592;Fisher's exact test, genotype, X2=2.9107, P-value = 0.2333 More... No significant association was observed. No significant association was observed. Negative Kim, S. H.,2011
rs4650608 PTGFR IFI44L 3(2/0/1) 2
P-value=1.77E-04 for BP, P-value=5.53E-13 for BP+SZ, Het P-...... P-value=1.77E-04 for BP, P-value=5.53E-13 for BP+SZ, Het P-value=0.85 More... Most significant SNP in six genome-wide significant regions...... Most significant SNP in six genome-wide significant regions. More... Negative Ruderfer, D. M., 2013
Conditional FDR; SCZ loci given BD: P-value=0.000206, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000206, FDR=0.257, FDR=0.028 for SCZ and BD||Conditional FDR; BD loci given SCZ: FDR=0.0425 for BD and SCZ||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.043 for BD and SZ, Z-score=3.711 for SZ More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.08. This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. This SNP is with conjunction FDR<0.06 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs334558 GSK3B 3(0/0/3) 1
Pheterogeneity=0.266, I2=23.2 %; OR=1...... Pheterogeneity=0.266, I2=23.2 %; OR=1.12, 95 % CI: 1.01, 1.25 More... C allele demonstrated more risk than T allele in schizophre...... C allele demonstrated more risk than T allele in schizophrenia. No evidence to imply the publication bias was observed by Begg’s funnel plot. And Egger's test further provided statistical support. More... Positive Tang, H., 2013
rs736408 ITIH3 3(1/2/0) 1
P-value = 0.021,OR= 0.874 P-value = 0.021,OR= 0.874 Significant association was observed. Significant association was observed. Positive Kondo, K.,2013
rs6903874 TAAR6 3(1/0/2) 1
Allele frequency (SZ vs.control) 0.14 vs. 0.09; X2 Allele frequency (SZ vs.control) 0.14 vs. 0.09; X2(df=1)= 6.28, P-value = 0.012 More... The minor allele (C) of SNP rs6903874 was significantly ove...... The minor allele (C) of SNP rs6903874 was significantly over-represented among the patients with schizophrenia compared to controls. More... Positive Pae, C. U., 2008
rs1954175 DISC1 TSNAX 3(0/0/3) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.093 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs2278749 ARNTL 3(1/0/2) 1
not analyzed for Pittsburgh SZ/SZA not analyzed for Pittsburgh SZ/SZA Negative Mansour, H. A., 2006
rs3736544 CLOCK TMEM165 3(1/0/2) 1
chi-square test: 1. total samples: P-value = 0.296(Genotype...... chi-square test: 1. total samples: P-value = 0.296(Genotype), P-value = 0.317(Allele) in SCZ 2. male samples: P-value = 0.830(Genotype), P-value = 0.985(Allele) in SCZ 3. female samples: P-value = 0.218(Genotype), P-value = 0.191(Allele) in SCZ More... We did not find an association between these tag SNPs and J...... We did not find an association between these tag SNPs and Japanese schizophrenia, BP or MDD in any of the analyses. More... Negative Kishi, T.,2009(a)
rs821597 DISC1 TSNAX 3(0/0/3) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.16 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs138880 BRD1 3(1/0/2) 2
P-value = 0.45, OR=1.09 in UK/DK sample P-value = 0.45, OR=1.09 in UK/DK sample Nominal significant association with SZ Nominal significant association with SZ Positive Nyegaard, M., 2010
P-value = 0.0061 in SZ, P-value = 0.0046 in BD and SZ P-value = 0.0061 in SZ, P-value = 0.0046 in BD and SZ The promoter SNP rs138880 showed association in SZ and the ...... The promoter SNP rs138880 showed association in SZ and the combined case group. More... Positive Severinsen, J. E., 2006 (b)
rs646558 NCAM1 3(1/0/2) 1
Fisher's exact test, allelic P-value = 1 in SZ; Fisher's ex...... Fisher's exact test, allelic P-value = 1 in SZ; Fisher's exact test, allelic P-value = 0.602 in BD&SZ; Heterozygous genotypic association (A/A-C/A): chi-square P-value = 0.01, X2=6.6, OR(95%CI)=0.054 (0.003-1.16); Homozygous genotypic association (C/C-A/A): chi-square P-value = 0.049, X2=3.86, OR(95%CI)=9.57 [0.47-193.92]; Allele positivity [(C/C+C/A)-A/A]: chi-square P-value = 0.027, X2=4.88, OR(95%CI)=0.084 [0.004-1.67] in SZ More... The SNP heterozygote and homozygote associations were signi...... The SNP heterozygote and homozygote associations were significant, as well as allele positivity for SZ, showing a suggestion of association. More... Positive Atz, M. E., 2007
rs1997644 CSNK1E 3(2/0/1) 2
Chi square test:MAF = 0.38,P-value = 0.89,OR = 0.99 Chi square test:MAF = 0.38,P-value = 0.89,OR = 0.99 No significant association was observed. No significant association was observed. Negative Matsunaga, S.,2012
Single SNP-based analyses:Trends test P-value = 0.363 in SZ Single SNP-based analyses:Trends test P-value = 0.363 in SZ No significant association was observed No significant association was observed Negative Mansour, H. A.,2009
rs715505 SYNGR1 3(1/0/2) 1
Fisher's exact test:allele P-value = 0.00007, chi-square te...... Fisher's exact test:allele P-value = 0.00007, chi-square test:genotype P-value = 0.0004 in SCZ More... Significant association was observed in allelic association...... Significant association was observed in allelic association. More... Positive Verma, R.,2005(a)
rs6988339 NRG1 3(2/0/1) 2
Individual P-value = 0.0103 for SCZ , Individual P-value = ...... Individual P-value = 0.0103 for SCZ , Individual P-value = 0.0058 for SCZ and BP More... This marker is nominally significant in the combined sample This marker is nominally significant in the combined sample Positive Thomson, P. A., 2007
X2 test:P-value = 0.01 for Scottish 1, P-value =...... X2 test:P-value = 0.01 for Scottish 1, P-value = 0.55 for Scottish 2, P-value = 0.38 for German, P-value = 0.024 for merged Scottish, P-value = 0.22 for merged all More... Significant association was found. Significant association was found. Positive Walker, R. M.,2010
rs9315897 DGKH 3(0/0/3) 1
Allelic association:P-value = 0.583, permutated P-value = 1...... Allelic association:P-value = 0.583, permutated P-value = 1 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs2279574 DUSP6 3(3/0/0) 2
chi-square P-value = 0.9205, Permutation P-value = 0.9992, ...... chi-square P-value = 0.9205, Permutation P-value = 0.9992, X2=0.01, OR=1.012; chi-square P-value = 0.8087, Permutation P-value = 1, X2=0.0586, OR=1.047 for female subjects, chi-square P-value = 0.7677, Permutation P-value = 0.93, X2=0.0872, OR=0.954 for male subjects More... showed nominally significant allelic associations with BD, ...... showed nominally significant allelic associations with BD, but not with SPR, in female patients More... Negative Kim, S. H., 2012 (a)
allelic P-value = 0.911, genotypic P-value = 0.991 for tota...... allelic P-value = 0.911, genotypic P-value = 0.991 for total patients; allelic P-value = 0.95, genotypic P-value = 0.865 for male patients; allelic P-value = 0.776, genotypic P-value = 0.95 for female patients with schizophrenia More... G allele was not different between schizophrenic patients a...... G allele was not different between schizophrenic patients and controls. When allele and genotype distribution were compared between the bipolar and schizophrenia groups, no significant difference was found. However, G allele was observed more commonly in bipolar females than their schizophrenic counterparts. More... Negative Lee, K. Y., 2006 (a)
rs37022 SLC6A3 3(1/0/2) 1
Stanley sample:allele, X2 P-value = 0.81, Fisher...... Stanley sample:allele, X2 P-value = 0.81, Fisher's exact P-value = 0.86OR=0.91 for SZ More... No significant association was observed. No significant association was observed. Negative Pinsonneault, J. K.,2011
rs2282586 GRIK4 2(1/0/1) 1
P-value = 0.358 between SCZ cases and controls; P-value = 0...... P-value = 0.358 between SCZ cases and controls; P-value = 0.058 between all cases and controls More... Negative Pickard, B. S., 2006
rs6932590 POM121L2 2(1/0/1) 1
Association results in schizophrenia follow-up samples(10,6...... Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.10 (1.05, 1.14),P-value = 2.5 x 10-5 More... No significant association was observed. No significant association was observed. Negative Steinberg, S.,2012
rs901561 NRG1 2(1/0/1) 1
Individual P-value = 0.7958 for SCZ , Individual P-value = ...... Individual P-value = 0.7958 for SCZ , Individual P-value = 0.9163 for SCZ and BP More... Negative Thomson, P. A., 2007
rs1978340 GAD1 2(1/0/1) 1
Fisher's exact test:for SZ, in Scottish sample set, P-value...... Fisher's exact test:for SZ, in Scottish sample set, P-value(allele)=0.57, P-value(genotype)=0.74 More... No significant association was observed. No significant association was observed. Negative Lundorf, M. D.,2005
rs734551 DISC1 TSNAX 2(0/0/2) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.89 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs2073831 BTF3P11 KCTD12 2(0/1/1) 1
All ethnicities: OR=1.07, 95%CI =0.90-1.28, P-value=0.445; ...... All ethnicities: OR=1.07, 95%CI =0.90-1.28, P-value=0.445; Malay: OR=0.68, 95%CI =0.49-0.95, P-value=0.025; Chinese: OR=1.35, 95%CI =1.04-1.74, P-value=0.024; Indian: OR=1.18, 95%CI =0.81-1.70, P-value=0.387 More... KCTD12 rs2073831 was significantly associated with SZ in Ma...... KCTD12 rs2073831 was significantly associated with SZ in Malays and Chinese (P= 0.024 and 0.025, respectively). More... Positive Lim C.H., 2014
rs988748 BDNF 2(0/0/2) 1
Armitage Trend Test:in Bonn sample, for Schizophrenia, P-va...... Armitage Trend Test:in Bonn sample, for Schizophrenia, P-value(odds ratio)=0.418(1.07) More... No significant association was observed. No significant association was observed. Negative Schumacher, J.,2005
rs3757930 NRG1 2(0/0/2) 2
X2 test:P-value = 0.2 for Scottish 1, P-value = ...... X2 test:P-value = 0.2 for Scottish 1, P-value = 0.69 for Scottish 2, P-value = 0.16 for German, P-value = 0.17 for merged Scottish, P-value = 0.85 for merged all More... No significant association was observed. No significant association was observed. Negative Walker, R. M.,2010
Individual P-value = 0.2035 for SCZ , Individual P-value = ...... Individual P-value = 0.2035 for SCZ , Individual P-value = 0.1164 for SCZ and BP More... Negative Thomson, P. A., 2007
rs10462021 PER3 2(0/0/2) 2
Single SNP-based analyses:Trends test P-value = 0.036 in SZ Single SNP-based analyses:Trends test P-value = 0.036 in SZ Significant association was observed Significant association was observed Positive Mansour, H. A.,2009
TDT P-value = 0.485, Trends test=0.913 for Pittsburgh SZ/SZ...... TDT P-value = 0.485, Trends test=0.913 for Pittsburgh SZ/SZA More... Negative Mansour, H. A., 2006
rs751229 DISC1 TSNAX 2(0/0/2) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.25 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs11098403 NDST3 2(1/0/1) 1
meta, P-value=2.67E-08 (OR=1.15, 95% confidence interval (C...... meta, P-value=2.67E-08 (OR=1.15, 95% confidence interval (CI): 1.08-1.21) when considering the schizophrenia cohorts alone; meta P-value=9.49E-12 (OR=1.13; 95% CI: 1.08-1.17) when all cohorts were included. Replication P-value=9.74E-04 for SZ when considering the non-discovery cohorts alone; Overall replication, P-value=1.46E-07; OR=1.09; 95% CI: 1.04-1.14 More... The top single-nucleotide polymorphism (SNP; rs11098403) de...... The top single-nucleotide polymorphism (SNP; rs11098403) demonstrates consistent effects across 11 replication and extension cohorts, totalling 23, 191 samples across multiple ethnicities, resulting in Pmeta=2.67 x 10(-8) (OR=1.15, 95% CI: 1.08-1.21) for schizophrenia alone. More... Positive Lencz, T., 2013
rs11736084 GPR78 2(0/0/2) 1
no P-value given in the text no P-value given in the text No single-marker association was detected. No single-marker association was detected. Negative Underwood, S. L., 2006
rs138855 BRD1 2(0/0/2) 2
P-value = 0.93, OR=1.01 in UK/DK sample P-value = 0.93, OR=1.01 in UK/DK sample Nominal significant association with SZ Nominal significant association with SZ Positive Nyegaard, M., 2010
P-value = 0.501 in SZ, P-value = 0.4186 in BD and SZ P-value = 0.501 in SZ, P-value = 0.4186 in BD and SZ Negative Severinsen, J. E., 2006 (b)
rs327329 NRG1 2(0/0/2) 2
X2 test:P-value = 0.44 for Scottish 1, P-value =...... X2 test:P-value = 0.44 for Scottish 1, P-value = 0.99 for Scottish 2, P-value = 0.56 for merged Scottish More... No significant association was observed. No significant association was observed. Negative Walker, R. M.,2010
Individual P-value = 0.4418 for SCZ , Individual P-value = ...... Individual P-value = 0.4418 for SCZ , Individual P-value = 0.7353 for SCZ and BP More... Negative Thomson, P. A., 2007
rs9799720 GPR78 2(1/0/1) 1
no P-value given in the text no P-value given in the text No single-marker association was detected. No single-marker association was detected. Negative Underwood, S. L., 2006
rs4532 DRD1 2(2/0/0) 2
no P-value provided no P-value provided With respect to schizophrenia, no significant association w...... With respect to schizophrenia, no significant association was found by a random effects model. More... Negative Zhang, J., 2013
no P-value no P-value With respect to schizophrenia, no significant association w...... With respect to schizophrenia, no significant association was found by a random effects model. More... Negative Yao, J., 2013
rs2020934 SLC6A4 2(0/0/2) 1
allelic P-value = 0.594, genotypic P-value = 0.161, Power c...... allelic P-value = 0.594, genotypic P-value = 0.161, Power calculation GRR=1.51 More... No associations of 'tagging' marker with SCZ was found. No associations of 'tagging' marker with SCZ was found. Negative Ikeda, M., 2006
rs553950 NRG1 2(2/0/0) 2
Individual P-value = 0.0288 for SCZ , Individual P-value = ...... Individual P-value = 0.0288 for SCZ , Individual P-value = 0.0109 for SCZ and BP More... This SNP is nominally significant in all three groups: BP, ...... This SNP is nominally significant in all three groups: BP, SCZ and combined. More... Positive Thomson, P. A., 2007
X2 test:P-value = 0.028 for Scottish 1, P-value ...... X2 test:P-value = 0.028 for Scottish 1, P-value = 0.99 for Scottish 2, P-value = 0.093 for merged Scottish More... Significant association was found. Significant association was found. Positive Walker, R. M.,2010
rs969486 ARNTL 2(1/0/1) 1
not analyzed for Pittsburgh SZ/SZA not analyzed for Pittsburgh SZ/SZA Negative Mansour, H. A., 2006
rs2076137 MLC1 2(0/0/2) 2
chi-square tests, P-value > 0.05 chi-square tests, P-value > 0.05 No association with the combined patient sample, SCZ or typ...... No association with the combined patient sample, SCZ or type A or type B schizophrenia was found. More... Negative Selch, S., 2007
Case-control association:for SCZ, Fisher exact test, allele...... Case-control association:for SCZ, Fisher exact test, allele P-value = 0.03; chi-square test, genotype P-value(additive)=0.02, P-value(dominant)=0.01, P-value(recessive)>0.05 ;Family-Based Association:for SCZ, TDT, P-value > 0.05 More... Significant association was observed in case-control associ...... Significant association was observed in case-control association analysis. More... Positive Verma, R.,2005(b)
rs6352 SLC6A4 2(0/0/2) 1
allelic P-value = 0.541, genotypic P-value = 0.911, Power c...... allelic P-value = 0.541, genotypic P-value = 0.911, Power calculation GRR=1.95 More... Asn605Lys showed weak association with SCZ, but the positiv...... Asn605Lys showed weak association with SCZ, but the positive association can not be confirmed in an additional analysis More... Negative Ikeda, M., 2006
rs769390 GAD1 2(0/0/2) 1
Fisher's exact test:for SZ, in Scottish sample set, P-value...... Fisher's exact test:for SZ, in Scottish sample set, P-value(allele)=0.8, P-value(genotype)=0.85 More... No significant association was observed. No significant association was observed. Negative Lundorf, M. D.,2005
rs133070 MCHR1 GAPDHP37 2(1/0/1) 1
CLUMP T1 P-value = 0.2107, CLUMP T4 P-value = 0.2107 for SZ...... CLUMP T1 P-value = 0.2107, CLUMP T4 P-value = 0.2107 for SZ; CLUMP T1 P-value = 0.0116, CLUMP T4 P-value = 0.0116 for BPD and SZ in the Faeroese Sample; Empirical overall P-value = 0.3638 for SZ in the Case-Control Sample From Scotland; Empirical overall P-value = 0.6721 for BPD and SZ in the Case-Control Sample From Scotland More... In BPD and BPD/SZ combined, single marker association was o...... In BPD and BPD/SZ combined, single marker association was observed for rs909669 (ADSL) and rs133070 (GPR24) with P-values between 0.0036 and 0.037. More... Positive Severinsen, J. E., 2006 (a)
rs1024582 CACNA1C CACNA1C-IT3 2(2/0/0) 1
Association analysis:P-value = 0.0000000187,OR(95%CI) = 1.0...... Association analysis:P-value = 0.0000000187,OR(95%CI) = 1.07(1.05-1.10) when BD and SZ were combined More... Significant association was observed in cross-disorder anal...... Significant association was observed in cross-disorder analysis. More... Positive Cross-Disorder Group of the Psychiatric Genomics Consortium,2013
rs2241514 FEZ1 2(0/0/2) 2
Allelic P-value = 0.510, genotypic P-value = 0.788 in Cau...... Allelic P-value = 0.510, genotypic P-value = 0.788 in Caucasians. Allelic P-value = 0.911, genotypic P-value = 0.964 in African Americans. More... No association to schizophrenia was found for any of the ni...... No association to schizophrenia was found for any of the nine markers typed in these populations at the allelic or the genotypic level. More... Negative Hodgkinson, C. A., 2007
Association analysis:Fisher's exact test, allele P-value = ...... Association analysis:Fisher's exact test, allele P-value = 0.77, genotype P-value = 0.853 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Yamada, K.,2004
rs61865882 EGR2 ADO 2(1/0/1) 1
For SZ, chi-square tests:allele, OR=1.27, X2=1.2...... For SZ, chi-square tests:allele, OR=1.27, X2=1.2985, P-value = 0.2545, P-value(permutation)=0.7578;Fisher's exact test, genotype, X2=1.5969, P-value = 0.45 More... No significant association was observed. No significant association was observed. Negative Kim, S. H.,2011
rs13440581 GPR50 GPR50-AS1 2(1/0/1) 1
Single marker association:for SCZ, allele P-value = 0.3(all...... Single marker association:for SCZ, allele P-value = 0.3(all), P-value = 0.84(male), P-value = 0.4(female) More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(b)
rs472913 NFIX 2(0/1/1) 1
P-value = 0.036,OR= 0.888 P-value = 0.036,OR= 0.888 Significant association was observed. Significant association was observed. Positive Kondo, K.,2013
rs12966547 CCDC68 2(2/0/0) 2
Association analysis:P-value = 0.00000000026 when BPD,MDD a...... Association analysis:P-value = 0.00000000026 when BPD,MDD and SZ were combined. More... Significant association was observed in cross-disorder anal...... Significant association was observed in cross-disorder analysis. More... Positive Cross-Disorder Group of the Psychiatric Genomics Consortium,2013
Conditional FDR; SCZ loci given BD: P-value=0.00000623, FDR...... Conditional FDR; SCZ loci given BD: P-value=0.00000623, FDR=0.071, FDR=0.019 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs2494732 AKT1 SIVA1 2(1/0/1) 2
Association analysis:chi square=4.90;df=1;P-value = 0.02;P-...... Association analysis:chi square=4.90;df=1;P-value = 0.02;P-value(adjusted)>0.05;OR(95%CI)=1.57(1.0-2.3) More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Karege, F.,2012
single-locus analysis:z=1.73;P-value = 0.083 single-locus analysis:z=1.73;P-value = 0.083 No significant association was observed. No significant association was observed. Negative Karege, F.,2010
rs2709736 RPL23P8 SP8 2(1/1/0) 1
P-value = 0.025,OR= 0.871 P-value = 0.025,OR= 0.871 Significant association was observed. Significant association was observed. Positive Kondo, K.,2013
rs3924999 NRG1 2(0/0/2) 1
For SZ:0.45/0.50 model:Pearson Chi-Square/P-value = 0.6/0.4...... For SZ:0.45/0.50 model:Pearson Chi-Square/P-value = 0.6/0.43, Yates Chi-Square/P-value = 10.28/0.25, Pearson Chi-Square/P-value = 10.55/0.21;Dominant model:Pearson Chi-Square/P-value = 0.08/0.77, Yates Chi-Square/P-value = 0.13/0.71, Pearson Chi-Square/P-value = 0.2/0.65 More... No significant association was observed. No significant association was observed. Negative Moon, E.,2011
rs133069 MCHR1 GAPDHP37 2(0/0/2) 1
CLUMP T1 P-value = 0.01, CLUMP T4 P-value = 0.01 for SZ; CL...... CLUMP T1 P-value = 0.01, CLUMP T4 P-value = 0.01 for SZ; CLUMP T1 P-value = 0.074, CLUMP T4 P-value = 0.074 for BPD and SZ in the Faeroese Sample; Empirical overall P-value = 0.8734 for SZ in the Case-Control Sample From Scotland; Empirical overall P-value = 0.7126 for BPD and SZ in the Case-Control Sample From Scotland More... The three GPR24 SNPs rs133068, rs133069, and rs133073 showe...... The three GPR24 SNPs rs133068, rs133069, and rs133073 showed association with SZ yielding P-values of 0.008-0.02. More... Positive Severinsen, J. E., 2006 (a)
rs878567 HTR1A 2(1/0/1) 1
For SZ, chi-square tests:genotype, P-value = 0.0606, correc...... For SZ, chi-square tests:genotype, P-value = 0.0606, corrected P-value = 0.286;allele, P-value = 0.0238 More... No significant association was observed. No significant association was observed. Negative Kishi, T.,2011(b)
rs951266 CHRNA5 2(1/0/1) 1
P-value=0.15, OR=1.05, 95% CI=(1.02-1.18) in SZD; P-value=0...... P-value=0.15, OR=1.05, 95% CI=(1.02-1.18) in SZD; P-value=0.009, OR=1.07, 95% CI=(1.02-1.13) in SZD + BD; P-value=0.017, OR=1.19, 95% CI=(1.03-1.37) in SZD with the presence of negative symptoms of schizophrenia More... When the schizophrenia and bipolar disorder results were co...... When the schizophrenia and bipolar disorder results were combined, four markers, rs951266, rs16969968, rs8040868, and rs17487223, were significantly associated with risk for schizophrenia and bipolar disorder. A meta-analysis of the results revealed a significant association with the variants rs951266, rs1051730, rs8040868, and rs1748722, and the presence of negative symptoms. More... Positive Jackson, K. J., 2013
rs41279104 NOS1 2(0/0/2) 1
Association analysis:X2=2.9, genotypic P-value =...... Association analysis:X2=2.9, genotypic P-value = 0.58 More... No significant association was observed. No significant association was observed. Negative Silberberg, G.,2010
rs2709722 RPL23P8 SP8 2(1/1/0) 1
P-value = 0.0024,OR= 0.82;P-value = 0.049,P-vorrection = 0....... P-value = 0.0024,OR= 0.82;P-value = 0.049,P-vorrection = 0.098,OR = 0.922 for replication. More... Significant association was observed. Significant association was observed. Positive Kondo, K.,2013
rs17025005 NPAS2 2(1/0/1) 1
Single SNP-based analyses:Trends test P-value = 0.085 in SZ Single SNP-based analyses:Trends test P-value = 0.085 in SZ No significant association was observed No significant association was observed Negative Mansour, H. A.,2009
rs12807809 NRGN 2(1/0/1) 1
Association results in schizophrenia follow-up samples(10,6...... Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.09 (1.04, 1.15),P-value = 0.00034 More... No significant association was observed. No significant association was observed. Negative Steinberg, S.,2012
rs11637898 ST8SIA2 2(2/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs1615409 TSNAX DISC1 2(0/0/2) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.86 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs2239848 BRD1 2(0/0/2) 2
P-value = 0.8, OR=0.9 in UK/DK sample P-value = 0.8, OR=0.9 in UK/DK sample Nominal significant association with SZ Nominal significant association with SZ Positive Nyegaard, M., 2010
P-value = 1 in SZ, P-value = 0.3983 in BD and SZ P-value = 1 in SZ, P-value = 0.3983 in BD and SZ Negative Severinsen, J. E., 2006 (b)
rs4279178 GABRB1 ADM 2(1/1/0) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs27072 SLC6A3 2(1/0/1) 1
Stanley sample:allele, X2 P-value = 0.91, Fisher...... Stanley sample:allele, X2 P-value = 0.91, Fisher's exact P-value = 1OR=1.05;U. of Bari sample X2 P-value = 0.69 for SZ More... No significant association was observed. No significant association was observed. Negative Pinsonneault, J. K.,2011
rs2702009 FEZ1 2(0/0/2) 2
Allelic P-value = 0.994, genotypic P-value = 0.900 in Cau...... Allelic P-value = 0.994, genotypic P-value = 0.900 in Caucasians. Allelic P-value = 0.962, genotypic P-value = 0.363 in African Americans. More... No association to schizophrenia was found for any of the ni...... No association to schizophrenia was found for any of the nine markers typed in these populations at the allelic or the genotypic level. More... Negative Hodgkinson, C. A., 2007
Association analysis:Fisher's exact test, allele P-value = ...... Association analysis:Fisher's exact test, allele P-value = 1, genotype P-value = 0.243 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Yamada, K.,2004
rs1800629 LTA TNF 2(1/0/1) 1
The frequency of the TNF -308G allele was 87.9% in SCH pati...... The frequency of the TNF -308G allele was 87.9% in SCH patients and 82.9% in control subjects, which was statistically significant (p = 0.008). The frequency of the TNF -308G/G genotype was significantly (p = 0.018) higher in patients than in controls (76.7 vs. 68.9%). More... Our results may point to an association of the TNF -308G al...... Our results may point to an association of the TNF -308G allele and -308G/G genotype with both SCH and BPAD, and to a relationship of the -308G allele with the risk of SCH and BPAD in patients with a positive family history. TNF could be potentially a susceptibility gene, shared between SCH and BPAD. More... Positive Czerski, P. M., 2008
rs2279287 ARNTL 2(1/0/1) 1
TDT P-value = 0.348, Trends test=0.173 for Pittsburgh SZ/SZ...... TDT P-value = 0.348, Trends test=0.173 for Pittsburgh SZ/SZA More... Negative Mansour, H. A., 2006
rs1538979 DISC1 2(1/0/1) 1
(CC+CT)>CC:for SZ, in the left postcentral gyrus (P-value c...... (CC+CT)>CC:for SZ, in the left postcentral gyrus (P-value corrected=0.001, z=4.39) for the sentence completion versus baseline. More... The schizophrenia group activation was significantly increa...... The schizophrenia group activation was significantly increased in those carrying the risk allele of rs1538979 compared to non-carriers in the left postcentral gyrus for the sentence completion versus baseline. More... Positive Chakirova, G.,2011
rs10776799 NGF 2(1/0/1) 1
Conditional FDR; BD loci given SCZ: FDR=0.02579 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.02579 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs4468 BRD1 2(1/0/1) 2
P-value = 0.61, OR=1.05 in UK/DK sample P-value = 0.61, OR=1.05 in UK/DK sample Nominal significant association with SZ Nominal significant association with SZ Positive Nyegaard, M., 2010
P-value = 0.0088 in SZ, P-value = 0.0215 in BD and SZ P-value = 0.0088 in SZ, P-value = 0.0215 in BD and SZ SNP rs4468 and D22S1169 showed significant association with...... SNP rs4468 and D22S1169 showed significant association with SZ but not with BPD. More... Positive Severinsen, J. E., 2006 (b)
rs2235349 MLC1 2(1/0/1) 2
chi-square tests, P-value > 0.05 chi-square tests, P-value > 0.05 No association with the combined patient sample, SCZ or typ...... No association with the combined patient sample, SCZ or type A or type B schizophrenia was found. More... Negative Selch, S., 2007
Case-control association:for SCZ, Fisher exact test, allele...... Case-control association:for SCZ, Fisher exact test, allele P-value = 0.03; chi-square test, genotype P-value(additive)=0.02, P-value(dominant)=0.006, P-value(recessive)>0.05;Family-Based Association:for SCZ, TDT, P-value > 0.05 More... Significant association was observed in case-control associ...... Significant association was observed in case-control association analysis. More... Positive Verma, R.,2005(b)
rs7004633 MMP16 2(1/0/1) 2
Conditional FDR; SCZ loci given BD: P-value=0.00000017, FDR...... Conditional FDR; SCZ loci given BD: P-value=0.00000017, FDR=0.018, FDR=0.005 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
First-set screening: P-valuecorrected=0.65, P-va...... First-set screening: P-valuecorrected=0.65, P-value=0.0155, OR=0.83, 95%CI=0.71-0.96 More... Significant association was observed. Significant association was observed. Positive Saito T., 2014
rs4792938 GRN 2(1/0/1) 2
Tagging single nucleotide polymorphisms (SNPs) rs2879096 an...... Tagging single nucleotide polymorphisms (SNPs) rs2879096 and rs4792938, along with rs5848, previously shown to be associated with BD and schizophrenia More... Positive Galimberti, D., 2014
Association analysis:chi square test, genotype P-value = 0...... Association analysis:chi square test, genotype P-value = 0.002, OR: 0.48, 95%CI: 0.31-0.77;allele P-value > 0.05 More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Galimberti, D.,2012
rs2038636 DISC1 TSNAX 2(0/0/2) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.83 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs3916971 DAOA-AS1 DAOA 2(0/0/2) 1
Fisher P-value = 0.0919 for all, P-value = 0.0919 for SCZ O...... Fisher P-value = 0.0919 for all, P-value = 0.0919 for SCZ Only More... Negative Detera-Wadleigh, S. D., 2006
rs613993 IMPA2 2(0/0/2) 1
Fisher's exact test, allelic P-value = 0.54, genotypic P-va...... Fisher's exact test, allelic P-value = 0.54, genotypic P-value = 0.628 More... Negative Ohnishi, T., 2007
rs1944522 GRIK4 2(0/0/2) 1
P-value = 0.842 between SCZ cases and controls; P-value = 0...... P-value = 0.842 between SCZ cases and controls; P-value = 0.405 between all cases and controls More... Negative Pickard, B. S., 2006
rs2297489 EGR2 2(1/0/1) 1
For SZ, chi-square tests:allele, OR=1.183, X2=0....... For SZ, chi-square tests:allele, OR=1.183, X2=0.7552, P-value = 0.3848, P-value(permutation)=0.909;Fisher's exact test, genotype, X2=2.1678, P-value = 0.3383 More... No significant association was observed. No significant association was observed. Negative Kim, S. H.,2011
rs7341475 RELN 2(0/0/2) 1
two-tail X2 test:GG genotype, P-value = 0.035 fo...... two-tail X2 test:GG genotype, P-value = 0.035 for females More... A significant effect was only seen in females. A significant effect was only seen in females. Positive Pisante, A.,2009
rs16969968 CHRNA3 CHRNA5 2(1/0/1) 1
P-value=0.09, OR=1.06, 95% CI=(0.97-1.13) in SZD; P-value=0...... P-value=0.09, OR=1.06, 95% CI=(0.97-1.13) in SZD; P-value=0.04, OR=1.06, 95% CI=(1-1.11) in SZD + BD; P-value=0.07, OR=1.15, 95% CI=(0.99-1.34) in SZD with the presence of negative symptoms of schizophrenia More... When the schizophrenia and bipolar disorder results were co...... When the schizophrenia and bipolar disorder results were combined, four markers, rs951266, rs16969968, rs8040868, and rs17487223, were significantly associated with risk for schizophrenia and bipolar disorder. More... Positive Jackson, K. J., 2013
rs133068 MCHR1 GAPDHP37 2(0/0/2) 1
CLUMP T1 P-value = 0.0197, CLUMP T4 P-value = 0.0197 for SZ...... CLUMP T1 P-value = 0.0197, CLUMP T4 P-value = 0.0197 for SZ; CLUMP T1 P-value = 0.1461, CLUMP T4 P-value = 0.1461 for BPD and SZ in the Faeroese Sample; Empirical overall P-value = 0.8145 for SZ in the Case-Control Sample From Scotland; Empirical overall P-value = 0.8538 for BPD and SZ in the Case-Control Sample From Scotland More... The three GPR24 SNPs rs133068, rs133069, and rs133073 showe...... The three GPR24 SNPs rs133068, rs133069, and rs133073 showed association with SZ yielding P-values of 0.008-0.02. More... Positive Severinsen, J. E., 2006 (a)
rs2291739 TIMELESS ARHGEF5 2(1/0/1) 1
not analyzed for Pittsburgh SZ/SZA not analyzed for Pittsburgh SZ/SZA Negative Mansour, H. A., 2006
rs1509963 EGR2 ADO 2(0/0/2) 1
For SZ, chi-square tests:allele, OR=1.119, X2=0....... For SZ, chi-square tests:allele, OR=1.119, X2=0.8177, P-value = 0.3659, P-value(permutation)=0.8934;Fisher's exact test, genotype, X2=1.2583, P-value = 0.533 More... No significant association was observed. No significant association was observed. Negative Kim, S. H.,2011
rs9960767 TCF4 TCF7L2 2(0/0/2) 1
Association results in schizophrenia follow-up samples(10,6...... Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.14 (1.06, 1.23),P-value = 0.00057 More... No significant association was observed. No significant association was observed. Negative Steinberg, S.,2012
rs1705236 TSPAN8 2(0/1/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs3803300 ZBTB42 AKT1 2(2/0/0) 2
Association analysis:chi square=4.40;df=1;P-value = 0.04;P-...... Association analysis:chi square=4.40;df=1;P-value = 0.04;P-value(adjusted)>0.05;OR(95%CI)=2.11(1.0-4.4).Meta analysis:The p-value based on the z statistic was (z=4.75) P-value < 0.0001. More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Karege, F.,2012
single-locus analysis:z=1.80;P-value = 0.072 single-locus analysis:z=1.80;P-value = 0.072 No significant association was observed. No significant association was observed. Negative Karege, F.,2010
rs2168351 ST8SIA2 2(2/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs6010260 MLC1 2(0/0/2) 2
P-value = 0.0823 in SZ, P-value = 0.1631 in BD and SZ P-value = 0.0823 in SZ, P-value = 0.1631 in BD and SZ Negative Severinsen, J. E., 2006 (b)
Case-control association:for SCZ, Fisher exact test, allele...... Case-control association:for SCZ, Fisher exact test, allele P-value > 0.05; chi-square test, genotype P-value(additive)>0.05, P-value(dominant)>0.05, P-value(recessive)>0.05 ;Family-Based Association:for SCZ, TDT, P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(b)
rs909685 SYNGR1 2(1/0/1) 1
Fisher's exact test:allele P-value = 0.007, chi-square test...... Fisher's exact test:allele P-value = 0.007, chi-square test:genotype P-value = 0.025 in SCZ More... Significant association was observed in allelic association...... Significant association was observed in allelic association. More... Positive Verma, R.,2005(a)
rs1042779 ITIH1 2(1/1/0) 1
P-value = 0.012,OR= 1.16 P-value = 0.012,OR= 1.16 Significant association was observed. Significant association was observed. Positive Kondo, K.,2013
rs464049 SLC6A3 2(1/0/1) 1
Stanley sample:allele, X2 P-value = 0.88, Fisher...... Stanley sample:allele, X2 P-value = 0.88, Fisher's exact P-value = 1OR=0.96 for SZ More... No significant association was observed. No significant association was observed. Negative Pinsonneault, J. K.,2011
rs5848 GRN FAM171A2 2(1/0/1) 2
Tagging single nucleotide polymorphisms (SNPs) rs2879096 an...... Tagging single nucleotide polymorphisms (SNPs) rs2879096 and rs4792938, along with rs5848, previously shown to be associated with BD and schizophrenia More... Positive Galimberti, D., 2014
Association analysis:chi square test, genotype P-value = 0...... Association analysis:chi square test, genotype P-value = 0.01, OR: 0.51, 95%CI: 0.30-0.85;allele P-value < 0.0001, OR: 0.53, 95%CI: 0.39-0.72 More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Galimberti, D.,2012
rs746187 DAOA 2(0/0/2) 1
Fisher P-value = 0.5966 for all, P-value = 0.5966 for SCZ O...... Fisher P-value = 0.5966 for all, P-value = 0.5966 for SCZ Only More... Negative Detera-Wadleigh, S. D., 2006
rs40184 SLC6A3 2(1/0/1) 1
Stanley sample:allele, X2 P-value = 0.61, Fisher...... Stanley sample:allele, X2 P-value = 0.61, Fisher's exact P-value = 0.64OR=1.17 for SZ More... No significant association was observed. No significant association was observed. Negative Pinsonneault, J. K.,2011
rs2759346 DISC1 TSNAX 2(1/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.83 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs2072621 GPR50 GPR50-AS1 2(0/0/2) 1
Single marker association:for SCZ, allele P-value = 0.31(al...... Single marker association:for SCZ, allele P-value = 0.31(all), P-value = 0.16(male), P-value = 0.0014(female) More... Association was not observed in SCZ, but was in observed S...... Association was not observed in SCZ, but was in observed SCZ(female). More... Negative Thomson, P. A.,2005(b)
rs6494223 CHRNA7 2(0/0/2) 1
Association analysis:allele P-value > 0.05, genotype P-valu...... Association analysis:allele P-value > 0.05, genotype P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Joo, E. J.,2010
rs3786282 IMPA2 2(0/0/2) 1
Fisher's exact test, allelic P-value = 0.965, genotypic P-v...... Fisher's exact test, allelic P-value = 0.965, genotypic P-value = 1 More... Negative Ohnishi, T., 2007
rs3749034 GAD1 2(0/0/2) 1
Fisher's exact test:for SZ, in Scottish sample set, P-value...... Fisher's exact test:for SZ, in Scottish sample set, P-value(allele)=0.61, P-value(genotype)=0.071 More... No significant association was observed. No significant association was observed. Negative Lundorf, M. D.,2005
rs1503491 NRG1 2(0/0/2) 2
X2 test:P-value = 0.61 for Scottish 1, P-value =...... X2 test:P-value = 0.61 for Scottish 1, P-value = 0.94 for Scottish 2, P-value = 0.86 for merged Scottish More... No significant association was observed. No significant association was observed. Negative Walker, R. M.,2010
Individual P-value = 0.609 for SCZ , Individual P-value = 0...... Individual P-value = 0.609 for SCZ , Individual P-value = 0.7019 for SCZ and BP More... Negative Thomson, P. A., 2007
rs2304672 PER2 2(1/0/1) 1
Single SNP-based analyses:Trends test P-value = 0.048 in SZ Single SNP-based analyses:Trends test P-value = 0.048 in SZ Significant association was observed Significant association was observed Positive Mansour, H. A.,2009
rs4356203 PIK3C2A 2(1/0/1) 2
P-value=2.14E-05 for BP, P-value=5.53E-13 for BP+SZ, Het P-...... P-value=2.14E-05 for BP, P-value=5.53E-13 for BP+SZ, Het P-value=0.85 More... Most significant SNP in six genome-wide significant regions...... Most significant SNP in six genome-wide significant regions. More... Negative Ruderfer, D. M., 2013
Conditional FDR; SCZ loci given BD: P-value=0.0000548, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000548, FDR=0.128, FDR=0.029 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs133073 MCHR1 2(0/0/2) 1
CLUMP T1 P-value = 0.0083, CLUMP T4 P-value = 0.0083 for SZ...... CLUMP T1 P-value = 0.0083, CLUMP T4 P-value = 0.0083 for SZ; CLUMP T1 P-value = 0.0546, CLUMP T4 P-value = 0.0546 for BPD and SZ in the Faeroese Sample; Empirical overall P-value = 0.8469 for SZ in the Case-Control Sample From Scotland; Empirical overall P-value = 0.5632 for BPD and SZ in the Case-Control Sample From Scotland More... The three GPR24 SNPs rs133068, rs133069, and rs133073 showe...... The three GPR24 SNPs rs133068, rs133069, and rs133073 showed association with SZ yielding P-values of 0.008-0.02. More... Positive Severinsen, J. E., 2006 (a)
rs1053454 PIP4K2A 2(0/0/2) 1
ARMITAGE P-value = 0.430 for Schizophrenia ARMITAGE P-value = 0.430 for Schizophrenia In the single marker analysis, none of the analyzed variant...... In the single marker analysis, none of the analyzed variants revealed significant association to disease status, neither for schizophrenia nor for BPAD. More... Negative Jamra, R. A., 2006 (a)
rs909669 ADSL 2(1/0/1) 1
CLUMP T1 P-value = 0.1178, CLUMP T4 P-value = 0.1178 for SZ...... CLUMP T1 P-value = 0.1178, CLUMP T4 P-value = 0.1178 for SZ; CLUMP T1 P-value = 0.0036, CLUMP T4 P-value = 0.0036 for BPD and SZ in the Faeroese Sample; Empirical overall P-value = 0.0655 for SZ in the Case-Control Sample From Scotland; Empirical overall P-value = 0.2189 for BPD and SZ in the Case-Control Sample From Scotland More... In BPD and BPD/SZ combined, single marker association was o...... In BPD and BPD/SZ combined, single marker association was observed for rs909669 (ADSL) and rs133070 (GPR24) with P-values between 0.0036 and 0.037. More... Positive Severinsen, J. E., 2006 (a)
rs6295 HTR1A 2(2/0/0) 1
For SZ, chi-square tests:genotype, P-value = 0.12;allele, P...... For SZ, chi-square tests:genotype, P-value = 0.12;allele, P-value = 0.146;meta analysis:random model:pooled OR=0.793, 95% CI=0.387-1.623, P(Z)=0.526 More... No significant association was observed. No significant association was observed. Negative Kishi, T.,2011(b)
rs2879096 GRN 2(1/0/1) 2
Tagging single nucleotide polymorphisms (SNPs) rs2879096 an...... Tagging single nucleotide polymorphisms (SNPs) rs2879096 and rs4792938, along with rs5848, previously shown to be associated with BD and schizophrenia More... Positive Galimberti, D., 2014
Association analysis:chi square test, genotype P-value = 0...... Association analysis:chi square test, genotype P-value = 0.0002, OR: 0.35, 95%CI: 0.20-0.61;allele P-value > 0.05 More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Galimberti, D.,2012
rs1996147 EGR3 2(1/0/1) 1
Single SNP-based analyses:Trends test P-value = 0.193 in SZ Single SNP-based analyses:Trends test P-value = 0.193 in SZ No significant association was observed No significant association was observed Negative Mansour, H. A.,2009
rs13025524 NPAS2 2(1/0/1) 1
Single SNP-based analyses:Trends test P-value = 0.025 in SZ Single SNP-based analyses:Trends test P-value = 0.025 in SZ Significant association was observed Significant association was observed Positive Mansour, H. A.,2009
rs716934 DGKH 2(0/0/2) 1
Allelic association:P-value = 0.658, permutated P-value = 1...... Allelic association:P-value = 0.658, permutated P-value = 1 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs2111902 DAO DAOA 2(0/0/2) 1
chi-squared tests:for SCZ, allele, X2(1 d.f.)=0....... chi-squared tests:for SCZ, allele, X2(1 d.f.)=0.025, P-value = 0.875 More... No significant association was observed. No significant association was observed. Negative Bass, N. J.,2009
rs597570 FEZ1 2(0/0/2) 2
Allelic P-value = 0.586, genotypic P-value = 0.696 in Cau...... Allelic P-value = 0.586, genotypic P-value = 0.696 in Caucasians. Allelic P-value = 0.858, genotypic P-value = 0.812 in African Americans. More... No association to schizophrenia was found for any of the ni...... No association to schizophrenia was found for any of the nine markers typed in these populations at the allelic or the genotypic level. More... Negative Hodgkinson, C. A., 2007
Association analysis:Fisher's exact test, allele P-value = ...... Association analysis:Fisher's exact test, allele P-value = 0.457, genotype P-value = 0.024 More... Significant associations were found in SZ patients. Significant associations were found in SZ patients. Positive Yamada, K.,2004
rs1050565 BLMH SLC6A4 2(0/0/2) 1
allelic P-value = 0.343, genotypic P-value = 0.139, Power c...... allelic P-value = 0.343, genotypic P-value = 0.139, Power calculation GRR=1.47 More... No associations of 'tagging' marker with SCZ was found. No associations of 'tagging' marker with SCZ was found. Negative Ikeda, M., 2006
rs3131296 NOTCH4 2(1/0/1) 1
Association results in schizophrenia follow-up samples(10,6...... Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.15 (1.08, 1.21),P-value = 1.4 x 10-6 More... Suggestive association was found. Suggestive association was found. Trend Steinberg, S.,2012
rs1051730 CHRNA3 2(0/0/2) 1
P-value=0.19, OR=1.05, 95% CI=(0.97-1.13) in SZD; P-value=0...... P-value=0.19, OR=1.05, 95% CI=(0.97-1.13) in SZD; P-value=0.08, OR=1.05, 95% CI=(0.99-1.1) in SZD + BD; P-value=0.019, OR=1.19, 95% CI=(1.03-1.37) in SZD with the presence of negative symptoms of schizophrenia More... A meta-analysis of the results revealed a significant assoc...... A meta-analysis of the results revealed a significant association with the variants rs951266, rs1051730, rs8040868, and rs1748722, and the presence of negative symptoms. More... Positive Jackson, K. J., 2013
rs7005606 NRG1 2(2/0/0) 1
Several allelic associations were found in the entire pool ...... Several allelic associations were found in the entire pool of BD, but not in schizophrenia. More... Negative Gutierrez-Fernandez, A., 2014
rs17844778 GPR78 2(0/0/2) 1
no P-value given in the text no P-value given in the text No single-marker association was detected. No single-marker association was detected. Negative Underwood, S. L., 2006
rs17693963 2(1/0/1) 2
Conditional FDR; SCZ loci given BD: P-value=0.000000187, FD...... Conditional FDR; SCZ loci given BD: P-value=0.000000187, FDR=0.022, FDR=0.001 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.29. More... Positive Andreassen OA, 2013
P-value=3.27E-09 for BP, P-value=5.53E-13 for BP+SZ, Het P-...... P-value=3.27E-09 for BP, P-value=5.53E-13 for BP+SZ, Het P-value=0.85 More... Most significant SNP in six genome-wide significant regions...... Most significant SNP in six genome-wide significant regions. More... Positive Ruderfer, D. M., 2013
rs2076127 MLC1 2(0/0/2) 1
Case-control association:for SCZ, Fisher exact test, allele...... Case-control association:for SCZ, Fisher exact test, allele P-value > 0.05; chi-square test, genotype P-value(additive)>0.05, P-value(dominant)>0.05, P-value(recessive)>0.05 ;Family-Based Association:for SCZ, TDT, P-value = 0.004, major allele T/NT: 43/16 More... Significant association was observed in family based associ...... Significant association was observed in family based association analysis. More... Positive Verma, R.,2005(b)
rs3813034 SLC6A4 2(0/0/2) 1
allelic P-value = 0.557, genotypic P-value = 0.781, Power c...... allelic P-value = 0.557, genotypic P-value = 0.781, Power calculation GRR=1.49 More... No associations of 'tagging' marker with SCZ was found. No associations of 'tagging' marker with SCZ was found. Negative Ikeda, M., 2006
rs3916964 DAOA 2(0/0/2) 1
Fisher P-value = 0.1138 for all, P-value = 0.1138 for SCZ O...... Fisher P-value = 0.1138 for all, P-value = 0.1138 for SCZ Only More... Negative Detera-Wadleigh, S. D., 2006
rs9685931 GPR78 2(0/0/2) 1
no P-value given in the text no P-value given in the text No single-marker association was detected. No single-marker association was detected. Negative Underwood, S. L., 2006
rs2498804 AKT1 SIVA1 2(2/0/0) 1
single-locus analysis:z=2.47;P-value = 0.013 single-locus analysis:z=2.47;P-value = 0.013 Significant association was found. Significant association was found. Positive Karege, F.,2010
rs3749474 CLOCK TMEM165 2(0/0/2) 1
chi-square test: 1.total samples:P-value = 0.228(Genotype),...... chi-square test: 1.total samples:P-value = 0.228(Genotype), P-value = 0.412(Allele) in SCZ 2. male samples: P-value = 0.701(Genotype), P-value = 0.890(Allele) in SCZ 3. female samples: P-value = 0.181(Genotype), P-value = 0.345(Allele) in SCZ More... We did not find an association between these tag SNPs and J...... We did not find an association between these tag SNPs and Japanese schizophrenia, BP or MDD in any of the analyses. More... Negative Kishi, T.,2009(a)
rs1282 GPR78 2(1/0/1) 1
chi square allelic P-value = 0.044, OR (95% CI)=1.300 (1.00...... chi square allelic P-value = 0.044, OR (95% CI)=1.300 (1.006-1.679), genotypic P-value = 0.099, OR (95% CI)=2.164 (0.974-4.804) in SCZ; allelic P-value = 0.067, OR (95% CI)=1.233 (0.985-1.543), genotypic P-value = 0.142, OR (95% CI)=1.931 (0.932-4.002) in all cases; allelic P-value = 0.592, OR (95% CI)=1.093 (0.789-1.515), genotypic P-value = 0.862, OR (95% CI)=1.138 (0.415-3.121) in male SCZ; allelic P-value = 0.656, OR (95% CI)=1.070 (0.794-1.444), genotypic P-value = 0.905, OR (95% CI)=1.119 (0.443-2.827) in all male cases; allelic P-value = 0.015, OR (95% CI)=1.688 (1.104-2.581), genotypic P-value = 0.015, OR (95% CI)=5.991 (1.545-23.232) in female SCZ; allelic P-value = 0.035, OR (95% CI)=1.439 (1.025-2.021), genotypic P-value = 0.054, OR (95% CI)=3.976 (1.140-13.871) in all female cases More... Marginally significant allelic association was detected bet...... Marginally significant allelic association was detected between rs1282 (snp2) and SCZ; Only a trend toward significance (P<0.10) was detected between snp2 and SCZ at the genotype level; When restricting the allele and genotype frequency analysis to the female patients, a stronger association was detected between snp2 and SCZ; A weaker association was detected in the analysis of all affected females; The backwards logistic regression approach, where genotypes were declared as the independent variables and the model was adjusted for the effects of sex, confirmed the findings of the single-marker analysis. It identified SNP rs1282 as the only SNP to survive the variable selection and only in the SCZ model. More... Positive Underwood, S. L., 2006
rs11568190 MLC1 2(1/0/1) 1
Case-control association:for SCZ, Fisher exact test, allele...... Case-control association:for SCZ, Fisher exact test, allele P-value > 0.05; chi-square test, genotype P-value(additive)>0.05, P-value(dominant)>0.05, P-value(recessive)>0.05;Family-Based Association:for SCZ, TDT, P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(b)
rs11123857 NPAS2 2(1/0/1) 1
Single SNP-based analyses:Trends test P-value = 0.038 in SZ Single SNP-based analyses:Trends test P-value = 0.038 in SZ Significant association was observed Significant association was observed Positive Mansour, H. A.,2009
rs2021722 TRIM26 2(2/0/0) 2
Association analysis:OR=1.17, P-value = 5.8E-04 Association analysis:OR=1.17, P-value = 5.8E-04 Significant association was observed in SZ. Significant association was observed in SZ. Positive association was observed in SZ. Hamshere, M. L.,2012
First-set screening: P-valuecorrected=0.32, P-va...... First-set screening: P-valuecorrected=0.32, P-value=0.00759, OR=0.76, 95%CI=0.62-0.93 More... Significant association was observed. Significant association was observed. Positive Saito T., 2014
rs1170098 DGKH 2(0/0/2) 1
Allelic association:P-value = 0.628, permutated P-value = 1...... Allelic association:P-value = 0.628, permutated P-value = 1 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs1411771 DISC1 TSNAX 2(0/0/2) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.9 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs10954842 NRG1 1(0/0/1) 1
Individual P-value = 0.7634 for SCZ , Individual P-value = ...... Individual P-value = 0.7634 for SCZ , Individual P-value = 0.9317 for SCZ and BP More... Negative Thomson, P. A., 2007
rs2891232 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.2014 Alelle association:P-value = 0.2014 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs7169541 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs6468099 NRG1 1(0/0/1) 1
Individual P-value = 0.7519 for SCZ , Individual P-value = ...... Individual P-value = 0.7519 for SCZ , Individual P-value = 0.5716 for SCZ and BP More... Negative Thomson, P. A., 2007
rs10250103 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 1.123(0.95–1.32),allelic...... Association analysis:OR(95%CI) = 1.123(0.95–1.32),allelic P-value = 0.17,genotypic P-value = 0.0424 More... Significant association was observed . Significant association was observed . Positive Li, T.,2013
rs243287 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.1015 Alelle association:P-value = 0.1015 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs6602217 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000229, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000229, FDR=0.095, FDR=0.015 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs2396753 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 0.981(0.87–1.11),allelic...... Association analysis:OR(95%CI) = 0.981(0.87–1.11),allelic P-value = 0.763,genotypic P-value = 0.837 More... No significant association was found. No significant association was found. Negative Li, T.,2013
rs2312147 VRK2 1(0/0/1) 1
Association results in schizophrenia follow-up samples(10,6...... Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.07 (1.03, 1.11),P-value = 0.00023 More... No significant association was observed. No significant association was observed. Negative Steinberg, S.,2012
rs6461233 MAD1L1 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.02711 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.02711 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs2241940 SLC6A5 1(0/0/1) 1
data not shown data not shown In the single-marker analysis, none of the analyzed variant...... In the single-marker analysis, none of the analyzed variants revealed a significant association with disease. More... Negative Jamra, R. A., 2006 (b)
rs289585 DLC1 1(0/0/1) 1
logistic regression:P-value > E-05 logistic regression:P-value > E-05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs1701946 KLK8 KLK9 1(1/0/0) 1
Genotype frequency (df=2) X2=3.26, P value=0.20....... Genotype frequency (df=2) X2=3.26, P value=0.20. Allele frequency (df=1) X2=2.36, P value=0.12 in Patients with SZ vs controls. More... There was no significant difference in genotype or allele d...... There was no significant difference in genotype or allele distribution for any SNP between patients and controls for schizophrenia or major depression. More... Negative Izumi, A., 2008
rs3133226 GRIK4 1(0/0/1) 1
P-value = 0.806 between SCZ cases and controls; P-value = 0...... P-value = 0.806 between SCZ cases and controls; P-value = 0.904 between all cases and controls More... Negative Pickard, B. S., 2006
rs5746826 TBX1 GNB1L 1(0/0/1) 1
X2= 1.676, P-value = 0.196 for schizophrenia wh...... X2= 1.676, P-value = 0.196 for schizophrenia when compared with controls. More... None of the nine individual SNPs showed a positive associat...... None of the nine individual SNPs showed a positive association in the 'all affecteds' category. More... Negative Funke, B. H., 2007
rs281393 RASIP1 MAMSTR 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.01293 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.01293 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs10207288 ERBB4 1(0/0/1) 1
Chi square test: allele P-value = 0.889, OR=1.014;genotype ...... Chi square test: allele P-value = 0.889, OR=1.014;genotype P-value = 0.889, chi square=0.019 for SCZ More... No significant association was observed. No significant association was observed. Negative Chen, P.,2012
rs10515677 1(0/0/1) 1
logistic regression:for SZ new sample, OR=0.62, P-value = 7...... logistic regression:for SZ new sample, OR=0.62, P-value = 7.47E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs10095694 NRG1 1(1/0/0) 1
Individual P-value = 0.0087 for SCZ , Individual P-value = ...... Individual P-value = 0.0087 for SCZ , Individual P-value = 0.006 for SCZ and BP More... This marker is nominally significant in the combined sample This marker is nominally significant in the combined sample Positive Thomson, P. A., 2007
rs672607 BCL9 1(1/0/0) 1
Third-Stage Sample:for SZ, allele association P-value = 0.0...... Third-Stage Sample:for SZ, allele association P-value = 0.006, OR(95%CI)=0.82(0.72-0.94);Combined Third-Stage Sample, allele association P-value = 0.0000000000123, OR(98%CI)=0.79(0.74-0.85) More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Li, J.,2011(b)
rs4935752 GRIK4 1(1/0/0) 1
P-value = 0.001 between SCZ cases and controls; P-value = 0...... P-value = 0.001 between SCZ cases and controls; P-value = 0.022 between all cases and controls; Best global P-value (permutation corrected)=0.03 More... showed significant association with schizophrenia; SNP 15 r...... showed significant association with schizophrenia; SNP 15 remained significantly associated with schizophrenia after permutation analysis to counter multiple testing errors More... Positive Pickard, B. S., 2006
rs145827578 SLC1A2 1(0/0/1) 1
SZ: P-value=0.160 SZ: P-value=0.160 No significant associations were observed. No significant associations were observed. Negative Fiorentino, A., 2014
rs4513929 NRG1 1(0/0/1) 1
Individual P-value = 0.4213 for SCZ , Individual P-value = ...... Individual P-value = 0.4213 for SCZ , Individual P-value = 0.9227 for SCZ and BP More... Negative Thomson, P. A., 2007
rs6490121 NOS1 1(0/0/1) 1
X2 tests:allele P-value = 0.67 for SCZ. X2 tests:allele P-value = 0.67 for SCZ. No significant association was observed. No significant association was observed. Negative Schanze, D.,2011
rs28363170 SLC6A3 1(0/0/1) 1
Stanley sample:allele, X2 P-value = 0.29, Fisher...... Stanley sample:allele, X2 P-value = 0.29, Fisher's exact P-value = 0.36OR=0.72;U. of Bari sample X2 P-value = 0.67 for SZ More... No significant association was observed. No significant association was observed. Negative Pinsonneault, J. K.,2011
rs10276352 SP4 1(0/0/1) 1
Allelic association:Chinese Trios for Schizophrenia:TDT:Ris...... Allelic association:Chinese Trios for Schizophrenia:TDT:Risk allele is G, MAF=0.281, P-value = 0.526 More... No significant association was observed No significant association was observed Negative Zhou, X.,2009
rs2075209 SLC1A4 1(0/0/1) 1
no P-value no P-value Allele and haplotype frequencies did not differ between cas...... Allele and haplotype frequencies did not differ between cases and controls. More... Negative Skowronek, M. H., 2006
rs16949856 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs4580657 BANK1 1(0/0/1) 1
logistic regression:for SZ full sample, OR=0.61, P-value = ...... logistic regression:for SZ full sample, OR=0.61, P-value = 1.61E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs28729663 RABL2B 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000182, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000182, FDR=0.257, FDR=0.041 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs3764352 PPP1R1B STARD3 1(0/0/1) 1
Genotypic P-value = 0.582, Armitage's P-value = 0.419. alle...... Genotypic P-value = 0.582, Armitage's P-value = 0.419. allelic P-value = 0.434 in SZ. More... Single-marker in a sample set showed that PPP1R1B polymorph...... Single-marker in a sample set showed that PPP1R1B polymorphisms were not significantly associated with schizophrenia. More... Negative Yoshimi, A., 2008
rs2347501 NRG1 NRG1-IT3 1(0/0/1) 1
Individual P-value = 0.5084 for SCZ , Individual P-value = ...... Individual P-value = 0.5084 for SCZ , Individual P-value = 0.5315 for SCZ and BP More... Negative Thomson, P. A., 2007
rs671056 BCL9 1(0/0/1) 1
Third-Stage Sample:for SZ, allele association P-value = 0.6...... Third-Stage Sample:for SZ, allele association P-value = 0.63, OR(95%CI)=0.94(0.73-1.20);Combined Third-Stage Sample, allele association P-value = 0.48, OR(98%CI)=0.96(0.85-1.08) More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(b)
rs6347 SLC6A3 1(0/0/1) 1
Stanley sample:allele, X2 P-value = 0.6, Fisher'...... Stanley sample:allele, X2 P-value = 0.6, Fisher's exact P-value = 0.7OR=0.87;U. of Bari sample X2 P-value = 0.25 for SZ More... No significant association was observed. No significant association was observed. Negative Pinsonneault, J. K.,2011
rs1796330 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs159788 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00123, FDR=0....... Conditional FDR; SCZ loci given BD: P-value=0.00123, FDR=0.527, FDR=0.034 for SCZ and BD||Conditional FDR; BD loci given SCZ: FDR=0.0308 for BD and SCZ||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.034 for BD and SZ, Z-score=23.232 for SZ More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.63. This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. This SNP is with conjunction FDR<0.14 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs2279665 TIMELESS 1(1/0/0) 1
not analyzed for Pittsburgh SZ/SZA not analyzed for Pittsburgh SZ/SZA Negative Mansour, H. A., 2006
rs7014762 NRG1 1(1/0/0) 1
TDT P-value = 0.27, X2=1.2 TDT P-value = 0.27, X2=1.2 Positive Georgieva, L.,2008
rs3890379 CSNK1E 1(0/0/1) 1
Chi square test:MAF = 0.15,P-value = 0.49,OR = 1.06 Chi square test:MAF = 0.15,P-value = 0.49,OR = 1.06 No significant association was observed. No significant association was observed. Negative Matsunaga, S.,2012
rs1397552 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs760742 SYNGR1 1(0/0/1) 1
Fisher's exact test:allele P-value = 0.9, chi-square test:g...... Fisher's exact test:allele P-value = 0.9, chi-square test:genotype P-value = 0.3 in SCZ More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(a)
rs3133855 GRIK4 1(0/0/1) 1
P-value = 0.811 between SCZ cases and controls; P-value = 0...... P-value = 0.811 between SCZ cases and controls; P-value = 0.624 between all cases and controls More... Negative Pickard, B. S., 2006
rs3752826 YWHAE 1(0/0/1) 1
For SZ:allele, OR[95%CI]=0.95[0.84-1.071], P-value = 0.3855...... For SZ:allele, OR[95%CI]=0.95[0.84-1.071], P-value = 0.38553, P-permutation=0.997;genotype, P-value = 0.04423, P-permutation=0.4343 More... Significant association was found, but the significance was...... Significant association was found, but the significance was lost after permutation. More... Positive Liu, J,2011(b)
rs2280468 ACAN 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs34041110 YWHAE 1(0/0/1) 1
For SZ:allele, OR[95%CI]=1.05[0.93-1.18], P-value = 0.41938...... For SZ:allele, OR[95%CI]=1.05[0.93-1.18], P-value = 0.41938, P-permutation=0.9987;genotype, P-value = 0.62434, P-permutation=1 More... No significant association was observed. No significant association was observed. Negative Liu, J,2011(b)
rs10807187 MDGA1 1(0/0/1) 1
Single SNP analyses:allele, P-value = 0.848, OR[95%CI]=0.98...... Single SNP analyses:allele, P-value = 0.848, OR[95%CI]=0.9877[0.8702, 1.1211], genotype, P-value = 0.7578 for SZ More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(a)
rs2298278 SUFU 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00124, FDR=0....... Conditional FDR; SCZ loci given BD: P-value=0.00124, FDR=0.527, FDR=0.037 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs11074070 ST8SIA2 ENO1P2 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs4500567 TSPAN8 1(1/0/0) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs1130233 AKT1 1(1/0/0) 1
single-locus analysis:z=-0.45;P-value = 0.651 single-locus analysis:z=-0.45;P-value = 0.651 No significant association was observed. No significant association was observed. Negative Karege, F.,2010
rs2131431 YWHAE 1(0/0/1) 1
For SZ:allele, OR[95%CI]=1.11[0.96-1.28], P-value = 0.16479...... For SZ:allele, OR[95%CI]=1.11[0.96-1.28], P-value = 0.16479, P-permutation=0.882;genotype, P-value = 0.25971, P-permutation=0.9716 More... No significant association was observed. No significant association was observed. Negative Liu, J,2011(b)
rs2239037 CACNA1C 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.03928 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.03928 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs7825588 NRG1 1(0/0/1) 1
SZ vs. controls: allele frequency, X2= 0.16, P-v...... SZ vs. controls: allele frequency, X2= 0.16, P-value = 0.68; genotype distribution, X2 = 7.32, P-value = 0.03; HWE controls, P-value = 0.08; SZ, P-value =0.04. More... Significant Significant association was observed in genotyp...... Significant Significant association was observed in genotype distribution. More... Positive Pedrosa, E.,2009
rs10954811 NRG1 1(0/0/1) 1
Individual P-value = 0.6247 for SCZ , Individual P-value = ...... Individual P-value = 0.6247 for SCZ , Individual P-value = 0.8101 for SCZ and BP More... Negative Thomson, P. A., 2007
rs1869901 PLCB2 PLCB2-AS1 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000203, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000203, FDR=0.257, FDR=0.039 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs1481762 NRG1 NRG1-IT1 1(0/0/1) 1
Individual P-value = 0.5544 for SCZ , Individual P-value = ...... Individual P-value = 0.5544 for SCZ , Individual P-value = 0.5402 for SCZ and BP More... Negative Thomson, P. A., 2007
rs16944 IL1B 1(0/0/1) 1
Association analysis:chi square test, Schizophrenia v contr...... Association analysis:chi square test, Schizophrenia v controls: allele: chi square= 3.79, P-value = 0.051; OR = 1.50 (95% CI: 0.98 to 2.31); genotype: chi square= 4.26, P-value = 0.119. More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Papiol, S.,2004
rs11692886 SH3RF3 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000105, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000105, FDR=0.181, FDR=0.035 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.15. More... Positive Andreassen OA, 2013
rs17675844 USP46 1(0/0/1) 1
Allele-/genotype wise analyses:X2 test, allele P...... Allele-/genotype wise analyses:X2 test, allele P-value > 0.05;genotype P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Kushima, I.,2010
rs4842318 PAWR 1(0/0/1) 1
Hardy-Weinberg equilibrium P value=0.388, genotypic P value...... Hardy-Weinberg equilibrium P value=0.388, genotypic P value=0.822, allelic P value=0.161 for schizophrenia compared with controls. More... No association was detected with schizophrenia or MDD in al...... No association was detected with schizophrenia or MDD in allele/genotype-wise analyses. More... Negative Kishi, T., 2008 (a)
rs10462020 PER3 1(0/0/1) 1
TDT P-value = 0.317, Trends test=0.08 for Pittsburgh SZ/SZA TDT P-value = 0.317, Trends test=0.08 for Pittsburgh SZ/SZA Negative Mansour, H. A., 2006
rs3011267 GTF3C5 GFI1B 1(0/0/1) 1
logistic regression:P-value > E-05 logistic regression:P-value > E-05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs138864 BRD1 1(0/0/1) 1
P-value = 0.64, OR=1.06 in UK/DK sample P-value = 0.64, OR=1.06 in UK/DK sample Nominal significant association with SZ Nominal significant association with SZ Positive Nyegaard, M., 2010
rs895682 ARNTL 1(1/0/0) 1
TDT P-value = 0.697, Trends test=0.846 for Pittsburgh SZ/SZ...... TDT P-value = 0.697, Trends test=0.846 for Pittsburgh SZ/SZA More... Negative Mansour, H. A., 2006
rs17034977 HSP90B1 C12orf73 1(1/0/0) 1
chi-square genotypic P-value = 0.2349, allelic P-value = 0....... chi-square genotypic P-value = 0.2349, allelic P-value = 0.0901 for SZ cases in total samples More... No significant association was observed in single SNPs. How...... No significant association was observed in single SNPs. However, the result should be treated with caution, because there was a significant difference of gender between patients with schizophrenia and controls. More... Negative Kakiuchi, C., 2007 (a)
rs6732223 SRD5A2 1(0/0/1) 1
Single marker association:DOM Model, chi square=8.17, df=1,...... Single marker association:DOM Model, chi square=8.17, df=1, P-value = 0.0043;GENO Model, chi square=8.41, df=2, P-value = 0.015;ALLELIC Model, chi square=4.08, df=1, P-value = 0.043;TREND Model, chi square=4.01, df=1, P-value = 0.045 More... Significant association was found. Significant association was found. Positive Steen, N. E.,2010
rs640088 IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.926, genotypic P-v...... Fisher's exact test, allelic P-value = 0.926, genotypic P-value = 0.596 More... Negative Ohnishi, T., 2007
rs6467734 AKR1D1 1(0/0/1) 1
Single marker association:REC Model, chi square=4.16, df=1,...... Single marker association:REC Model, chi square=4.16, df=1, P-value = 0.041 More... Significant association was found. Significant association was found. Positive Steen, N. E.,2010
rs9656744 NRG1 1(0/0/1) 1
Individual P-value = 0.8711 for SCZ , Individual P-value = ...... Individual P-value = 0.8711 for SCZ , Individual P-value = 0.5984 for SCZ and BP More... Negative Thomson, P. A., 2007
rs137930 MOV10L1 MLC1 1(0/0/1) 1
Case-control association:for SCZ, Fisher exact test, allele...... Case-control association:for SCZ, Fisher exact test, allele P-value > 0.05; chi-square test, genotype P-value(additive)>0.05, P-value(dominant)>0.05, P-value(recessive)>0.05 ;Family-Based Association:for SCZ, TDT, P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(b)
rs1958022 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.6967 Alelle association:P-value = 0.6967 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs6994992 NRG1 1(0/0/1) 1
For SZ:0/1 model:Pearson Chi-Square/P-value = 0.01/0.92, Ya...... For SZ:0/1 model:Pearson Chi-Square/P-value = 0.01/0.92, Yates Chi-Square/P-value = 0/1, Pearson Chi-Square/P-value = 0.02/0.88;Dominant model:Pearson Chi-Square/P-value = 0.37/0.54, Yates Chi-Square/P-value = 0.19/0.66, Pearson Chi-Square/P-value = 0.3/0.58 More... No significant association was observed. No significant association was observed. Negative Moon, E.,2011
rs878989 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.8416 Alelle association:P-value = 0.8416 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs10883817 CNNM2 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000113, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000113, FDR=0.08, FDR=0.02 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs2640909 PER3 1(0/0/1) 1
Single SNP-based analyses:Trends test P-value = 0.031 in SZ Single SNP-based analyses:Trends test P-value = 0.031 in SZ Significant association was observed Significant association was observed Positive Mansour, H. A.,2009
rs6571608 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.772 Alelle association:P-value = 0.772 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs984402 RGS7 1(0/0/1) 1
logistic regression:for SZ full sample, OR=0.79, P-value = ...... logistic regression:for SZ full sample, OR=0.79, P-value = 3.43E-07 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs2075824 IMPA2 1(1/0/0) 1
Fisher's exact test, allelic P-value = 0.13, genotypic P-va...... Fisher's exact test, allelic P-value = 0.13, genotypic P-value = 0.24 More... Negative Ohnishi, T., 2007
rs3858917 ST8SIA2 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs6589832 GRIK4 1(0/0/1) 1
P-value = 0.6 between SCZ cases and controls; P-value = 0.8...... P-value = 0.6 between SCZ cases and controls; P-value = 0.833 between all cases and controls More... Negative Pickard, B. S., 2006
rs17005769 PAWR 1(0/0/1) 1
Hardy-Weinberg equilibrium P value=0.125, genotypic P value...... Hardy-Weinberg equilibrium P value=0.125, genotypic P value=0.254, allelic P value=0.414 for schizophrenia compared with controls. More... No association was detected with schizophrenia or MDD in al...... No association was detected with schizophrenia or MDD in allele/genotype-wise analyses. More... Negative Kishi, T., 2008 (a)
rs138820 BRD1 1(0/0/1) 1
P-value = 0.3, OR=1.12 in UK/DK sample P-value = 0.3, OR=1.12 in UK/DK sample Nominal significant association with SZ Nominal significant association with SZ Positive Nyegaard, M., 2010
rs137931 MOV10L1 MLC1 1(0/0/1) 1
P-value = 0.844 in SZ, P-value = 0.5796 in BD and SZ P-value = 0.844 in SZ, P-value = 0.5796 in BD and SZ Negative Severinsen, J. E., 2006 (b)
rs1798086 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs1954787 GRIK4 1(0/0/1) 1
P-value = 0.472 between SCZ cases and controls; P-value = 0...... P-value = 0.472 between SCZ cases and controls; P-value = 0.515 between all cases and controls More... Negative Pickard, B. S., 2006
rs6986716 NRG1 1(0/0/1) 1
Individual P-value = 0.991 for SCZ , Individual P-value = 0...... Individual P-value = 0.991 for SCZ , Individual P-value = 0.5832 for SCZ and BP More... Negative Thomson, P. A., 2007
rs1417374 PIP4K2A 1(0/0/1) 1
ARMITAGE P-value = 0.950 for Schizophrenia ARMITAGE P-value = 0.950 for Schizophrenia In the single marker analysis, none of the analyzed variant...... In the single marker analysis, none of the analyzed variants revealed significant association to disease status, neither for schizophrenia nor for BPAD. More... Negative Jamra, R. A., 2006 (a)
rs2902101 TENM2 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.0357 for BD and S...... Conditional FDR; BD loci given SCZ: FDR=0.0357 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs363420 SLC18A2 1(0/0/1) 1
chi-square genotypic P-value = 0.117 for SZ, P-value = 0.36...... chi-square genotypic P-value = 0.117 for SZ, P-value = 0.366 for BD and SZ; chi-square allelic P-value = 0.051 for SZ, P-value = 0.261 for BD and SZ; 2666C carriers P-value = 0.037, X2=4.33, OR (95%CI)=1.73 (1-3.01) More... showed significant allelic association with schizophrenia; ...... showed significant allelic association with schizophrenia; different frequencies between controls and patients with schizophrenia were detected; a significant increase of 2666C carriers was found in the group of schizophrenic subjects when compared to controls More... Positive Gutierrez, B., 2007
rs7090018 FGFR2 1(0/0/1) 1
Allelic association results:P-value = 0.154, Permutated P-v...... Allelic association results:P-value = 0.154, Permutated P-value = 0.81 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Wang, T.,2012
rs4777974 ST8SIA2 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs11122396 DISC1 TSNAX 1(0/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.51 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs346005 USP46 1(0/0/1) 1
Allele-/genotype wise analyses:X2 test, allele P...... Allele-/genotype wise analyses:X2 test, allele P-value > 0.05;genotype P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Kushima, I.,2010
rs17014011 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs760741 SYNGR1 1(0/0/1) 1
Fisher's exact test:allele P-value = 0.5, chi-square test:g...... Fisher's exact test:allele P-value = 0.5, chi-square test:genotype P-value = 0.9 in SCZ More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(a)
rs3829773 CSNK1D SLC16A3 1(0/0/1) 1
Chi square test:MAF = 0.09,P-value = 0.26,OR = 1.14 Chi square test:MAF = 0.09,P-value = 0.26,OR = 1.14 No significant association was observed. No significant association was observed. Negative Matsunaga, S.,2012
rs1952079 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.2359 Alelle association:P-value = 0.2359 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs10277665 THSD7A 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.01641 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.01641 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs4726220 ACTR3B 1(0/1/0) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs2241802 FZD3 RNA5SP259 1(0/0/1) 1
Allelic association:P-value = 0.85 for SZ Allelic association:P-value = 0.85 for SZ No significant association was observed in SZ. No significant association was observed in SZ. Negative Hashimoto, R.,2005(b)
rs1953432 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.5518 Alelle association:P-value = 0.5518 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs13190937 ZSCAN23 COX11P1 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000123, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000123, FDR=0.203, FDR=0.033 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.30. More... Positive Andreassen OA, 2013
rs406511 1(0/0/1) 1
logistic regression:P-value > E-05 logistic regression:P-value > E-05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs10240470 MAD1L1 1(1/0/0) 1
P-value = 0.090,OR= 1.17 P-value = 0.090,OR= 1.17 No significant association was observed. No significant association was observed. Negative Kondo, K.,2013
rs2306847 AKR1D1 1(0/0/1) 1
Single marker association:GENO Model, chi square=6.15, df=2...... Single marker association:GENO Model, chi square=6.15, df=2, P-value = 0.046 More... Significant association was found. Significant association was found. Positive Steen, N. E.,2010
rs944086 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.1349 Alelle association:P-value = 0.1349 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs17849952 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs16840252 CTLA4 1(0/0/1) 1
For SZ:allele, OR[95%CI]=0.7931[0.6680-0.9417], P-value = 0...... For SZ:allele, OR[95%CI]=0.7931[0.6680-0.9417], P-value = 0.0081, P-permutation=0.0665;genotype, P-value = 0.0117, P-permutation=0.0935 More... Significant association was found, but the significance was...... Significant association was found, but the significance was lost after permutation. More... Positive Liu, J,2011(a)
rs11210359 LRRIQ3 1(0/1/0) 1
chi suqare test:SZ v.BP, P-value = E-5.1;SZ v.C, P-value = ...... chi suqare test:SZ v.BP, P-value = E-5.1;SZ v.C, P-value = E-1 More... Suggestive association was found. Suggestive association was found. Trend Curtis, D.,2011
rs1959181 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.2241 Alelle association:P-value = 0.2241 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2524005 HLA-K HLA-U 1(0/0/1) 1
logistic regression:for SZ full sample, OR=0.74, P-value = ...... logistic regression:for SZ full sample, OR=0.74, P-value = 3.81E-07 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs738149 CSF2RB 1(0/0/1) 1
Single site association analysis:for SZ, allele, OR=1.208, ...... Single site association analysis:for SZ, allele, OR=1.208, P-value = 0.031 More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Chen, P.,2011
rs2289683 SLC6A5 1(0/0/1) 1
data not shown data not shown In the single-marker analysis, none of the analyzed variant...... In the single-marker analysis, none of the analyzed variants revealed a significant association with disease. More... Negative Jamra, R. A., 2006 (b)
rs3746972 ITGB2 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.04369 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.04369 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs9268858 HLA-DRB9 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000166, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000166, FDR=0.084, FDR=0.041 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs1532976 YWHAE 1(0/0/1) 1
For SZ:allele, OR[95%CI]=1.04[0.91-1.19], P-value = 0.37288...... For SZ:allele, OR[95%CI]=1.04[0.91-1.19], P-value = 0.37288, P-permutation=0.9965;genotype, P-value = 0.09601, P-permutation=0.6947 More... No significant association was observed. No significant association was observed. Negative Liu, J,2011(b)
rs7174649 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs1573745 ST13 1(0/0/1) 1
Empirical overall P-value = 0.2879 for SZ in the Case-Contr...... Empirical overall P-value = 0.2879 for SZ in the Case-Control Sample From Scotland; Empirical overall P-value = 0.7989 for BPD and SZ in the Case-Control Sample From Scotland More... Negative Severinsen, J. E., 2006 (a)
rs703657 HSP90B1 C12orf73 1(0/0/1) 1
chi-square genotypic P-value = 0.1065, allelic P-value = 0....... chi-square genotypic P-value = 0.1065, allelic P-value = 0.2814 for SZ cases in total samples More... No significant association was observed in single SNPs. How...... No significant association was observed in single SNPs. However, the result should be treated with caution, because there was a significant difference of gender between patients with schizophrenia and controls. More... Negative Kakiuchi, C., 2007 (a)
rs602104 GRIK4 HMGB1P42 1(1/0/0) 1
P-value = 0.425 between SCZ cases and controls; P-value = 0...... P-value = 0.425 between SCZ cases and controls; P-value = 0.028 between all cases and controls More... Positive Pickard, B. S., 2006
rs7326068 IFT88 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs739363 SYNGR1 1(0/0/1) 1
Fisher's exact test:allele P-value = 0.9, chi-square test:g...... Fisher's exact test:allele P-value = 0.9, chi-square test:genotype P-value = 0.8 in SCZ More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(a)
rs607200 IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.447, genotypic P-v...... Fisher's exact test, allelic P-value = 0.447, genotypic P-value = 0.692 More... Negative Ohnishi, T., 2007
rs2463169 PAWR 1(0/0/1) 1
Hardy-Weinberg equilibrium P value=0.329, genotypic P value...... Hardy-Weinberg equilibrium P value=0.329, genotypic P value=0.872, allelic P value=0.517 for schizophrenia compared with controls. More... No association was detected with schizophrenia or MDD in al...... No association was detected with schizophrenia or MDD in allele/genotype-wise analyses. More... Negative Kishi, T., 2008 (a)
rs4812829 HNF4A 1(1/0/0) 1
P-value=0.281, Pcorrected=1.0, OR=0.93 for SZ in screening ...... P-value=0.281, Pcorrected=1.0, OR=0.93 for SZ in screening stage, P-value=0.49, OR=1.03 for replication. More... No association was found for SZ. No association was found for SZ. Negative Kajio, Y., 2014
rs13380006 ST8SIA2 C15orf32 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs2171250 RNA5SP225 1(0/0/1) 1
logistic regression:P-value > E-05 logistic regression:P-value > E-05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs135764 CSNK1E 1(0/0/1) 1
Chi square test:MAF = 0.15,P-value = 0.48,OR = 0.94 Chi square test:MAF = 0.15,P-value = 0.48,OR = 0.94 No significant association was observed. No significant association was observed. Negative Matsunaga, S.,2012
rs6663779 FABP3 ZCCHC17 1(0/0/1) 1
allele test P-value = 0.8552, genotype test P-value = 0.851...... allele test P-value = 0.8552, genotype test P-value = 0.8512 More... None of the 8 SNPs showed association with schizophrenia. None of the 8 SNPs showed association with schizophrenia. Negative Iwayama, Y., 2010
rs1001021 MYO18B 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs769700 DUSP6 1(1/0/0) 1
chi-square P-value = 0.9919, Permutation P-value = 1, X chi-square P-value = 0.9919, Permutation P-value = 1, X2=0.0001, OR=0.9961; chi-square P-value = 0.4652, Permutation P-value = 0.8983, X2=0.5333, OR=1.559 for female subjects, chi-square P-value = 0.4958, Permutation P-value = 0.9196, X2=0.464, OR=0.7172 for male subjects More... showed nominally significant allelic associations with BD, ...... showed nominally significant allelic associations with BD, but not with SPR, in female patients More... Negative Kim, S. H., 2012 (a)
rs713809 MOV10L1 MLC1 1(0/0/1) 1
chi-square tests, P-value > 0.05 chi-square tests, P-value > 0.05 No association with the combined patient sample, SCZ or typ...... No association with the combined patient sample, SCZ or type A or type B schizophrenia was found. More... Negative Selch, S., 2007
rs3087243 CTLA4 1(0/0/1) 1
For SZ:allele, OR[95%CI]=0.9786[0.8416-1.1379], P-value = 0...... For SZ:allele, OR[95%CI]=0.9786[0.8416-1.1379], P-value = 0.7787, P-permutation=1;genotype, P-value = 0.9484, P-permutation=1 More... No significant association was observed. No significant association was observed. Negative Liu, J,2011(a)
rs1165681 HSP90B1 1(0/0/1) 1
chi-square genotypic P-value = 0.6237, allelic P-value = 0....... chi-square genotypic P-value = 0.6237, allelic P-value = 0.5015 for SZ cases in total samples More... No significant association was observed in single SNPs. How...... No significant association was observed in single SNPs. However, the result should be treated with caution, because there was a significant difference of gender between patients with schizophrenia and controls. More... Negative Kakiuchi, C., 2007 (a)
rs6900617 MDGA1 1(0/0/1) 1
Single SNP analyses:allele, P-value = 0.4061, OR[95%CI]=1.0...... Single SNP analyses:allele, P-value = 0.4061, OR[95%CI]=1.0553[0.9295, 1.1981], genotype, P-value = 0.3642 for SZ More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(a)
rs10245440 SP4 1(0/0/1) 1
Allelic association:Chinese Trios for Schizophrenia:TDT:Ris...... Allelic association:Chinese Trios for Schizophrenia:TDT:Risk allele is C, MAF=0.451, P-value = 0.955 More... No significant association was observed No significant association was observed Negative Zhou, X.,2009
rs1411776 DISC1 TSNAX 1(0/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.54 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs1952302 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.1587 Alelle association:P-value = 0.1587 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs1233710 ZKSCAN4 1(1/0/0) 1
First-set screening: P-valuecorrected=1, P-value...... First-set screening: P-valuecorrected=1, P-value=0.534, OR=1.04, 95%CI=0.91-1.19 More... No significant association was observed. No significant association was observed. Negative Saito T., 2014
rs2871042 TBX1 1(0/0/1) 1
X2= 0.114, P-value = 0.735 for schizophrenia w...... X2= 0.114, P-value = 0.735 for schizophrenia when compared with controls. More... None of the nine individual SNPs showed a positive associat...... None of the nine individual SNPs showed a positive association in the 'all affecteds' category. More... Negative Funke, B. H., 2007
rs17226863 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs4262150 NMUR2 1(0/0/1) 1
logistic regression:for SZ full sample, OR=0.81, P-value = ...... logistic regression:for SZ full sample, OR=0.81, P-value = 6.34E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs933226 C22orf24 YWHAH 1(0/0/1) 1
LRT P-value:0.44(Psychotic features), 0.82(Mood-incongruent...... LRT P-value:0.44(Psychotic features), 0.82(Mood-incongruent psychotic features) More... None of the SNPs showed any difference between observed and...... None of the SNPs showed any difference between observed and expected allelic transmissionswhen the mood-incongruent psychotic BP phenotype was used.And none of the SNPs were impacted by the moodincongruence covariate. More... Negative Grover, D.,2009
rs1018954 SP4 1(1/0/0) 1
Allelic association:Chinese Trios for Schizophrenia:TDT:Ris...... Allelic association:Chinese Trios for Schizophrenia:TDT:Risk allele is T, MAF=0.051, P-value = 0.129 More... No significant association was observed No significant association was observed Negative Zhou, X.,2009
rs2238777 TBX1 1(0/0/1) 1
X2= 1.379, P-value = 0.240 for schizophrenia wh...... X2= 1.379, P-value = 0.240 for schizophrenia when compared with controls. More... None of the nine individual SNPs showed a positive associat...... None of the nine individual SNPs showed a positive association in the 'all affecteds' category. More... Negative Funke, B. H., 2007
rs10893380 FEZ1 1(0/0/1) 1
Allelic P-value = 0.536, genotypic P-value = 0.450 in Cau...... Allelic P-value = 0.536, genotypic P-value = 0.450 in Caucasians. Allelic P-value = 0.716, genotypic P-value = 0.924 in African Americans. More... No association to schizophrenia was found for any of the ni...... No association to schizophrenia was found for any of the nine markers typed in these populations at the allelic or the genotypic level. More... Negative Hodgkinson, C. A., 2007
rs231775 CTLA4 1(0/0/1) 1
For SZ:allele, OR[95%CI]=1.0656[0.9388-1.2094], P-value = 0...... For SZ:allele, OR[95%CI]=1.0656[0.9388-1.2094], P-value = 0.3255, P-permutation=0.9425;genotype, P-value = 0.5025, P-permutation=0.9934 More... No significant association was observed. No significant association was observed. Negative Liu, J,2011(a)
rs3785817 GRN 1(0/0/1) 1
Association analysis:chi square test, genotype P-value > 0....... Association analysis:chi square test, genotype P-value > 0.05;allele P-value > 0.05 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Galimberti, D.,2012
rs10491929 RORB 1(1/0/0) 1
Single SNP-based analyses:Trends test P-value = 0.023 in SZ Single SNP-based analyses:Trends test P-value = 0.023 in SZ Significant association was observed Significant association was observed Positive Mansour, H. A.,2009
rs1958050 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.486 Alelle association:P-value = 0.486 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs4245040 GRIK4 1(0/0/1) 1
P-value = 0.39 between SCZ cases and controls; P-value = 0....... P-value = 0.39 between SCZ cases and controls; P-value = 0.25 between all cases and controls More... Negative Pickard, B. S., 2006
rs1481892 ARNTL 1(1/0/0) 1
not analyzed for Pittsburgh SZ/SZA not analyzed for Pittsburgh SZ/SZA Negative Mansour, H. A., 2006
rs17102287 FGFR2 1(0/0/1) 1
Allelic association results:P-value = 0.191, Permutated P-v...... Allelic association results:P-value = 0.191, Permutated P-value = 0.881 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Wang, T.,2012
rs199599866 SLC1A2 1(0/0/1) 1
SZ: P-value=0.398 SZ: P-value=0.398 No significant associations were observed. No significant associations were observed. Negative Fiorentino, A., 2014
rs946903 BCL9 ACP6 1(0/0/1) 1
Third-Stage Sample:for SZ, allele association P-value = 0.4...... Third-Stage Sample:for SZ, allele association P-value = 0.47, OR(95%CI)=0.95(0.83-1.10);Combined Third-Stage Sample, allele association P-value = 0.16, OR(98%CI)=0.95(0.89-1.02) More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(b)
rs821663 DISC1 TSNAX 1(0/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.12 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs1956002 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.2089 Alelle association:P-value = 0.2089 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs10994359 ANK3 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.00001 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.00001 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs9276601 HLA-DQB2 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000307, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000307, FDR=0.104, FDR=0.015 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs804831 MDGA1 1(0/0/1) 1
Single SNP analyses:allele, P-value = 0.6481, OR[95%CI]=0.9...... Single SNP analyses:allele, P-value = 0.6481, OR[95%CI]=0.9623[0.8160, 1.1349], genotype, P-value = 0.3841 for SZ More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(a)
rs166050 SRD5A1 1(1/0/0) 1
Single marker association:P-value > 0.05 in all model. Single marker association:P-value > 0.05 in all model. No significant association was observed. No significant association was observed. Negative Steen, N. E.,2010
rs774026 TIMELESS 1(0/0/1) 1
TDT P-value = 0.039, X2=4.25, df=1, Trends test=...... TDT P-value = 0.039, X2=4.25, df=1, Trends test=0.352 for Pittsburgh SZ/SZA More... When we analyzed transmission bias in the SZ/SZA samples, w...... When we analyzed transmission bias in the SZ/SZA samples, we observed significant transmission distortion at this loci. More... Positive Mansour, H. A., 2006
rs7157101 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.7983 Alelle association:P-value = 0.7983 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs3132780 GRIK4 1(0/0/1) 1
P-value = 0.464 between SCZ cases and controls; P-value = 0...... P-value = 0.464 between SCZ cases and controls; P-value = 0.514 between all cases and controls More... Negative Pickard, B. S., 2006
rs3836790 SLC6A3 1(0/0/1) 1
Stanley sample:allele, X2 P-value = 0.8, Fisher'...... Stanley sample:allele, X2 P-value = 0.8, Fisher's exact P-value = 0.87OR=1.09;U. of Bari sample X2 P-value = 0.85 for SZ More... No significant association was observed. No significant association was observed. Negative Pinsonneault, J. K.,2011
rs1130214 AKT1 1(1/0/0) 1
single-locus analysis:z=-1.41;P-value = 0.158 single-locus analysis:z=-1.41;P-value = 0.158 No significant association was observed. No significant association was observed. Negative Karege, F.,2010
rs1984895 DISC1 TSNAX 1(0/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.95 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs4140862 ANO2 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs11191454 AS3MT 1(1/0/0) 1
Association analysis:P-value = 0.0000000139,OR(95%CI) = 1.1...... Association analysis:P-value = 0.0000000139,OR(95%CI) = 1.13(1.08–1.18) when five disorders were combined More... Significant association was observed in cross-disorder anal...... Significant association was observed in cross-disorder analysis. More... Positive Cross-Disorder Group of the Psychiatric Genomics Consortium,2013
rs6425744 FABP3 1(0/0/1) 1
allele test P-value = 0.6259, genotype test P-value = 0.246...... allele test P-value = 0.6259, genotype test P-value = 0.2468 More... None of the 8 SNPs showed association with schizophrenia. None of the 8 SNPs showed association with schizophrenia. Negative Iwayama, Y., 2010
rs3756179 CPZ GPR78 1(0/0/1) 1
no P-value given in the text no P-value given in the text No single-marker association was detected. No single-marker association was detected. Negative Underwood, S. L., 2006
rs909486 CSF2RB 1(0/0/1) 1
Single site association analysis:for SZ, allele, OR=1.176, ...... Single site association analysis:for SZ, allele, OR=1.176, P-value = 0.024 More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Chen, P.,2011
rs10503932 NRG1 1(0/0/1) 1
Individual P-value = 0.566 for SCZ , Individual P-value = 0...... Individual P-value = 0.566 for SCZ , Individual P-value = 0.494 for SCZ and BP More... Negative Thomson, P. A., 2007
rs971363 IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.36, genotypic P-va...... Fisher's exact test, allelic P-value = 0.36, genotypic P-value = 0.175 More... Negative Ohnishi, T., 2007
rs12427050 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.04728 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.04728 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs4624 ZBED4 1(0/0/1) 1
P-value = 0.87, OR=0.98 in UK/DK sample P-value = 0.87, OR=0.98 in UK/DK sample Nominal significant association with SZ Nominal significant association with SZ Positive Nyegaard, M., 2010
rs4982109 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.6317 Alelle association:P-value = 0.6317 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs10462018 PER3 1(0/0/1) 1
TDT P-value = 0.197, Trends test=0.878 for Pittsburgh SZ/SZ...... TDT P-value = 0.197, Trends test=0.878 for Pittsburgh SZ/SZA More... Negative Mansour, H. A., 2006
rs4663627 AGAP1 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000131, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000131, FDR=0.203, FDR=0.033 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.20. More... Positive Andreassen OA, 2013
rs559688 FEZ1 1(0/0/1) 1
Association analysis:Fisher's exact test, allele P-value = ...... Association analysis:Fisher's exact test, allele P-value = 0.703, genotype P-value = 0.014 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Yamada, K.,2004
rs1000730 DISC1 TSNAX 1(0/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.82 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs1539628 PIP4K2A 1(0/0/1) 1
ARMITAGE P-value = 0.544 for Schizophrenia ARMITAGE P-value = 0.544 for Schizophrenia In the single marker analysis, none of the analyzed variant...... In the single marker analysis, none of the analyzed variants revealed significant association to disease status, neither for schizophrenia nor for BPAD. More... Negative Jamra, R. A., 2006 (a)
rs12404162 DISC1 TSNAX 1(0/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.48 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs7178572 HMG20A 1(1/0/0) 1
P-value=0.25, Pcorrected=1, OR=0.93 for SZ in screening sta...... P-value=0.25, Pcorrected=1, OR=0.93 for SZ in screening stage, P-value=0.28, OR=1.05 for replication. More... No association was found for SZ. No association was found for SZ. Negative Kajio, Y., 2014
rs12673091 SP4 1(1/0/0) 1
Allelic association:Chinese Trios for Schizophrenia:TDT:Ris...... Allelic association:Chinese Trios for Schizophrenia:TDT:Risk allele is A, MAF=0.111, P-value = 0.012 More... Significant association was observed Significant association was observed Positive Zhou, X.,2009
rs10489202 MPC2 DCAF6 1(0/0/1) 1
First-set screening: P-valuecorrected=1, P-value...... First-set screening: P-valuecorrected=1, P-value=0.0267, OR=1.24, 95%CI=1.02-1.49 More... Significant association was observed. Significant association was observed. Positive Saito T., 2014
rs715519 MAPK8IP2 CHKB 1(0/0/1) 1
P-value = 0.7254 in SZ, P-value = 0.7976 in BD and SZ P-value = 0.7254 in SZ, P-value = 0.7976 in BD and SZ Negative Severinsen, J. E., 2006 (b)
rs231777 CTLA4 1(1/0/0) 1
For SZ:allele, OR[95%CI]=0.813[0.6827-0.9683], P-value = 0....... For SZ:allele, OR[95%CI]=0.813[0.6827-0.9683], P-value = 0.0201, P-permutation=0.1559;genotype, P-value = 0.0631, P-permutation=0.3912 More... Significant association was found, but the significance was...... Significant association was found, but the significance was lost after permutation. More... Positive Liu, J,2011(a)
rs10517263 USP46 1(0/0/1) 1
Allele-/genotype wise analyses:X2 test, allele P...... Allele-/genotype wise analyses:X2 test, allele P-value > 0.05;genotype P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Kushima, I.,2010
rs12646800 USP46 1(0/0/1) 1
Allele-/genotype wise analyses:X2 test, allele P...... Allele-/genotype wise analyses:X2 test, allele P-value = 0.04, P-value > 0.05 after Bonferroni correction;genotype P-value = 0.01, P-value > 0.05 after Bonferroni correction. More... No significant association was observed. No significant association was observed. Negative Kushima, I.,2010
rs1315142 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.6844 Alelle association:P-value = 0.6844 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs6459806 PTPRN2 1(0/1/0) 1
chi suqare test:SZ v.BP, P-value = E-5.1;SZ v.C, P-value = ...... chi suqare test:SZ v.BP, P-value = E-5.1;SZ v.C, P-value = E-1 More... Suggestive association was found. Suggestive association was found. Trend Curtis, D.,2011
rs769395 GAD1 1(0/0/1) 1
Fisher's exact test:for SZ, in Scottish sample set, P-value...... Fisher's exact test:for SZ, in Scottish sample set, P-value(allele)=0.8, P-value(genotype)=0.96 More... No significant association was observed. No significant association was observed. Negative Lundorf, M. D.,2005
rs7084499 ANK3 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000174, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000174, FDR=0.229, FDR=0.04 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs1805091 SLC6A5 1(0/0/1) 1
data not shown data not shown In the single-marker analysis, none of the analyzed variant...... In the single-marker analysis, none of the analyzed variants revealed a significant association with disease. More... Negative Jamra, R. A., 2006 (b)
rs433110 GRIK4 1(0/0/1) 1
P-value = 0.084 between SCZ cases and controls; P-value = 0...... P-value = 0.084 between SCZ cases and controls; P-value = 0.362 between all cases and controls More... Negative Pickard, B. S., 2006
rs2827775 1(0/0/1) 1
logistic regression:for SZ new sample, OR=0.8, P-value = 4....... logistic regression:for SZ new sample, OR=0.8, P-value = 4.73E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs2414718 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000459, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000459, FDR=0.128, FDR=0.025 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs7083127 CACNB2 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.02191 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.02191 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs10447760 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 0.377(0.21–0.68),allelic...... Association analysis:OR(95%CI) = 0.377(0.21–0.68),allelic P-value = 0.000698,genotypic P-value = 0.000643 More... Significant association was observed . Significant association was observed . Positive Li, T.,2013
rs381523 PPM1F 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00155, FDR=0....... Conditional FDR; SCZ loci given BD: P-value=0.00155, FDR=0.56, FDR=0.038 for SCZ and BD||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.04536 for BD and SCZ||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.045 for BD and SZ, Z-score=3.166 for SZ More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.63. This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. This SNP is with conjunction FDR<0.14 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs2291738 TIMELESS 1(1/0/0) 1
TDT P-value = 0.126, Trends test=0.256 for Pittsburgh SZ/SZ...... TDT P-value = 0.126, Trends test=0.256 for Pittsburgh SZ/SZA More... Negative Mansour, H. A., 2006
rs9621795 LARGE 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000166, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000166, FDR=0.084, FDR=0.041 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs644710 IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.933, genotypic P-v...... Fisher's exact test, allelic P-value = 0.933, genotypic P-value = 0.95 More... Negative Ohnishi, T., 2007
rs2156635 GRIK4 1(1/0/0) 1
P-value = 0.081 between SCZ cases and controls; P-value = 0...... P-value = 0.081 between SCZ cases and controls; P-value = 0.041 between all cases and controls More... Positive Pickard, B. S., 2006
rs11097431 PDLIM5 1(0/0/1) 1
For A vs. G: P-value=0.78, OR (95% CI)=0.96 (0.72-1.28) in ...... For A vs. G: P-value=0.78, OR (95% CI)=0.96 (0.72-1.28) in pooled samples; P-value=0.85, OR (95% CI)=0.96 (0.59-1.55) in Malay, P-value=0.29, OR (95% CI)=0.78 (0.50-1.23) in Chinese, P-value=0.45, OR (95% CI)=1.27 (0.68-2.38) in Indian; For G/A vs. G/G: P-value=0.58, OR (95% CI)=1.09 (0.81-1.47) in pooled sample, P-value=0.76, OR (95% CI)=1.08 (0.65-1.83) in Malay, P-value=0.64, OR (95% CI)=0.90 (0.57-1.42) in Chinese, P-value=0.34, OR (95% CI)=1.38 (0.72-2.66) in Indian; For A/A vs. G/G: P-value=0.77, OR (95% CI)=0.78 (0.14-4.32) in pooled sample, P-value=1.00, OR (95% CI)=1.00 (1.161-6.27) in Malay, P-value=1.00, OR (95% CI)=0 (0) in Chinese; For A/A vs. G/A +G/G: P-value=0.76, OR (95% CI)=0.77 (0.14-4.23) in pooled sample, P-value=0.99, OR (95% CI)=0.99 (0.16-6.14) in Malay, P-value=1.00, OR (95% CI)=0 (0) in Chinese; For G/A + A/A vs. G/G: P-value=0.62, OR (95% CI)=1.08 (0.80-1.45) in pooled sample, P-value=0.77, OR (95% CI)=1.09 (0.65-1.80) in Malay, P-value=0.58, OR (95% CI)=0.88 (0.56-1.39) in Chinese, P-value=0.34, OR (95% CI)=1.38 (0.72-2.66) in Indian More... No association was detected between the rs11097431 polymorp...... No association was detected between the rs11097431 polymorphism and schizophrenia in any of the three ethnicities. More... Negative Zain, M. A., 2013
rs2273773 SIRT1 1(0/0/1) 1
For SZ, X2 test:genotype, X2(2df)=0.0...... For SZ, X2 test:genotype, X2(2df)=0.0744, P-value = 0.963;allele, X2(2df)=0.0644, P-value = 0.8 More... No significant association was observed. No significant association was observed. Negative Kishi, T.,2011(a)
rs6468119 NRG1 1(1/0/0) 1
Several allelic associations were found in the entire pool ...... Several allelic associations were found in the entire pool of BD, but not in schizophrenia. More... Negative Gutierrez-Fernandez, A., 2014
rs1160491 DISC1 TSNAX 1(0/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.14 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs1041128 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.2404 Alelle association:P-value = 0.2404 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs971362 IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.238, genotypic P-v...... Fisher's exact test, allelic P-value = 0.238, genotypic P-value = 0.361 More... Negative Ohnishi, T., 2007
rs2896635 ARNTL 1(0/0/1) 1
TDT P-value = 0.933, Trends test=0.772 for Pittsburgh SZ/SZ...... TDT P-value = 0.933, Trends test=0.772 for Pittsburgh SZ/SZA More... Negative Mansour, H. A., 2006
rs1279338 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.0175 Alelle association:P-value = 0.0175 Significant association was observed Significant association was observed Positive Pickard, B. S.,2009
rs3117099 BTNL2 HCG23 1(0/0/1) 1
logistic regression:for SZ full sample, OR=0.79, P-value = ...... logistic regression:for SZ full sample, OR=0.79, P-value = 4.12E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs4982060 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.7784 Alelle association:P-value = 0.7784 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs923875 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 0.916(0.81–1.04),allelic...... Association analysis:OR(95%CI) = 0.916(0.81–1.04),allelic P-value = 0.164,genotypic P-value = 0.176 More... No significant association was found. No significant association was found. Negative Li, T.,2013
rs224278 EGR2 1(0/0/1) 1
For SZ, chi-square tests:allele, OR=0.979, X2=0....... For SZ, chi-square tests:allele, OR=0.979, X2=0.0268, P-value = 0.8698, P-value(permutation)=1;Fisher's exact test, genotype, X2=0.0339, P-value = 0.9832 More... No significant association was observed. No significant association was observed. Negative Kim, S. H.,2011
rs1883901 MDGA1 1(1/0/0) 1
Single SNP analyses:allele, P-value = 0.0242(0.3160), OR[95...... Single SNP analyses:allele, P-value = 0.0242(0.3160), OR[95%CI]=1.1929[1.0232, 1.3909], genotype, P-value = 0.0205(0.2756 after permutations) for SZ More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(a)
rs9922369 RPGRIP1L 1(0/0/1) 1
X2 tests:allele P-value = 0.39 for SCZ. X2 tests:allele P-value = 0.39 for SCZ. No significant association was observed. No significant association was observed. Negative Schanze, D.,2011
rs11222395 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000136, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000136, FDR=0.203, FDR=0.032 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs17040430 CMKLR1 1(0/0/1) 1
logistic regression:P-value > E-05 logistic regression:P-value > E-05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs363343 SLC18A2 1(0/0/1) 1
chi-square genotypic P-value = 0.516 for SZ, P-value = 0.40...... chi-square genotypic P-value = 0.516 for SZ, P-value = 0.405 for BD and SZ; chi-square allelic P-value = 0.499 for SZ, -value=0.743 for BD and SZ More... associations with the polymorphism were not detected with t...... associations with the polymorphism were not detected with the schizophrenic group More... Negative Gutierrez, B., 2007
rs1502404 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00104, FDR=0....... Conditional FDR; SCZ loci given BD: P-value=0.00104, FDR=0.489, FDR=0.04 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs2276319 GRIK4 1(0/0/1) 1
P-value = 0.94 between SCZ cases and controls; P-value = 0....... P-value = 0.94 between SCZ cases and controls; P-value = 0.675 between all cases and controls More... Negative Pickard, B. S., 2006
rs12916879 CHRNA7 1(0/0/1) 1
Association analysis:allele P-value > 0.05, genotype P-valu...... Association analysis:allele P-value > 0.05, genotype P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Joo, E. J.,2010
rs594235 IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.67, genotypic P-va...... Fisher's exact test, allelic P-value = 0.67, genotypic P-value = 0.475 More... Negative Ohnishi, T., 2007
rs588409 SNX3 NR2E1 1(0/0/1) 1
X2=0.78, OR (95% CI)=1.10 (0.88-1.43), P-value =...... X2=0.78, OR (95% CI)=1.10 (0.88-1.43), P-value = 0.378 for SZ. More... No association was detected with schizophrenia. No association was detected with schizophrenia. Negative Kumar, R. A., 2008
rs724729 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000047, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000047, FDR=0.128, FDR=0.038 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs7280842 SAMSN1 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs11178655 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs45602133 EGR2 1(1/0/0) 1
For SZ, chi-square tests:allele, OR=0.846, X2=0....... For SZ, chi-square tests:allele, OR=0.846, X2=0.7658, P-value = 0.3815, P-value(permutation)=0.9064;Fisher's exact test, genotype, X2=1.1279, P-value = 0.569 More... No significant association was observed. No significant association was observed. Negative Kim, S. H.,2011
rs733314 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.8784 Alelle association:P-value = 0.8784 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs7532813 ZCCHC17 FABP3 1(0/0/1) 1
allele test P-value = 0.6697, genotype test P-value = 0.581...... allele test P-value = 0.6697, genotype test P-value = 0.5818 More... None of the 8 SNPs showed association with schizophrenia. None of the 8 SNPs showed association with schizophrenia. Negative Iwayama, Y., 2010
rs4240467 GGTA1P 1(1/0/0) 1
SNPs in the chromosome 9q33.2 breakpoint region were not si...... SNPs in the chromosome 9q33.2 breakpoint region were not significantly associated with SZ (p>0.15). More... Negative Rajkumar, A. P., 2014
rs747226 TBX1 1(0/0/1) 1
X2= 0.510, P-value = 0.475 for schizophrenia wh...... X2= 0.510, P-value = 0.475 for schizophrenia when compared with controls. More... None of the nine individual SNPs showed a positive associat...... None of the nine individual SNPs showed a positive association in the 'all affecteds' category. More... Negative Funke, B. H., 2007
rs759458 SLC1A4 1(0/0/1) 1
no P-value no P-value Allele and haplotype frequencies did not differ between cas...... Allele and haplotype frequencies did not differ between cases and controls. More... Negative Skowronek, M. H., 2006
rs9326555 BCL9 1(0/0/1) 1
Third-Stage Sample:for SZ, allele association P-value = 0.1...... Third-Stage Sample:for SZ, allele association P-value = 0.15, OR(95%CI)=1.16(0.94-1.43);Combined Third-Stage Sample, allele association P-value = 0.0000153, OR(98%CI)=1.27(1.14-1.41) More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Li, J.,2011(b)
rs2183276 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.8232 Alelle association:P-value = 0.8232 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs513548 GRIK4 1(0/0/1) 1
P-value = 0.68 between SCZ cases and controls; P-value = 0....... P-value = 0.68 between SCZ cases and controls; P-value = 0.786 between all cases and controls More... Negative Pickard, B. S., 2006
rs1299512 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.4961 Alelle association:P-value = 0.4961 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs6459804 PTPRN2 1(0/1/0) 1
chi suqare test:SZ v.BP, P-value = E-5.1;SZ v.C, P-value = ...... chi suqare test:SZ v.BP, P-value = E-5.1;SZ v.C, P-value = E-1.1 More... Suggestive association was found. Suggestive association was found. Trend Curtis, D.,2011
rs9533042 DGKH 1(0/0/1) 1
Allelic association:P-value = 0.009, permutated P-value = 0...... Allelic association:P-value = 0.009, permutated P-value = 0.086 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs839523 ERBB4 1(0/0/1) 1
Chi square test: allele P-value = 0.264, OR=1.072;genotype ...... Chi square test: allele P-value = 0.264, OR=1.072;genotype P-value = 0.456, chi square=1.571 for SCZ More... No significant association was observed. No significant association was observed. Negative Chen, P.,2012
rs31745 PCDHA@ 1(1/0/0) 1
Allele frequency Pearson X2(df=1)= 0.45, asympto...... Allele frequency Pearson X2(df=1)= 0.45, asymptotic P-value = 0.50; genotype distribution X2 test for independence, Pearson X2(df=2)=1.28, exact P-value = 0.53 for SZ when compared with controls. Hardy-Weinberg equilibrium P-value = 0.66 for SZ. More... An increase in homozygotes for the T allele was also seen i...... An increase in homozygotes for the T allele was also seen in SZ patients, but the results were not statistically More... Negative Pedrosa, E., 2008
rs3730358 AKT1 1(1/0/0) 1
single-locus analysis:z=-0.30;P-value = 0.764 single-locus analysis:z=-0.30;P-value = 0.764 No significant association was observed. No significant association was observed. Negative Karege, F.,2010
rs3747158 C22orf24 YWHAH 1(1/0/0) 1
LRT P-value:0.01(Psychotic features), 0.82(Mood-incongruent...... LRT P-value:0.01(Psychotic features), 0.82(Mood-incongruent psychotic features) More... It had evidence of association with BP that was impacted by...... It had evidence of association with BP that was impacted by the psychotic features covariate. More... Positive Grover, D.,2009
rs7612463 UBE2E2 1(0/0/1) 1
P-value=0.021, Pcorrected=0.68, OR=1.23 for SZ in screening...... P-value=0.021, Pcorrected=0.68, OR=1.23 for SZ in screening stage. More... In the SCZ sample, only one SNP in UBE2E2 (rs7612463) showe...... In the SCZ sample, only one SNP in UBE2E2 (rs7612463) showed a nominal significant association (Puncorrected < 0.05). More... Positive Kajio, Y., 2014
rs10093464 NRG1 1(0/0/1) 1
Individual P-value = 0.6394 for SCZ , Individual P-value = ...... Individual P-value = 0.6394 for SCZ , Individual P-value = 0.9223 for SCZ and BP More... Negative Thomson, P. A., 2007
rs4733132 NRG1 1(0/0/1) 1
Individual P-value = 0.5628 for SCZ , Individual P-value = ...... Individual P-value = 0.5628 for SCZ , Individual P-value = 0.2859 for SCZ and BP More... Negative Thomson, P. A., 2007
rs352203 FZD3 1(0/0/1) 1
Allelic association:P-value = 0.97 for SZ Allelic association:P-value = 0.97 for SZ No significant association was observed in SZ. No significant association was observed in SZ. Negative Hashimoto, R.,2005(b)
rs194487 CTNND2 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs4765914 CACNA1C 1(1/0/0) 1
Association analysis:P-value = 0.0000000152 when BPD,MDD an...... Association analysis:P-value = 0.0000000152 when BPD,MDD and SZ were combined. More... Significant association was observed in cross-disorder anal...... Significant association was observed in cross-disorder analysis. More... Positive Cross-Disorder Group of the Psychiatric Genomics Consortium,2013
rs7690296 PDLIM5 1(1/0/0) 1
For G vs. A: P-value=0.81, OR (95% CI)=1.02 (0.86-1.22) in ...... For G vs. A: P-value=0.81, OR (95% CI)=1.02 (0.86-1.22) in pooled samples; P-value=0.08, OR (95% CI)=1.32 (0.97-1.80) in Malay, P-value=0.04, OR (95% CI)=0.75 (0.60-0.99) in Chinese, P-value=0.06, OR (95% CI)=1.43 (0.98-2.07) in Indian; For A/G vs. A/A: P-value=0.21, OR (95% CI)=0.83 (0.62-1.12) in pooled sample, P-value=0.59, OR (95% CI)=0.87 (0.52-1.45) in Malay, P-value=0.20, OR (95% CI)=0.75 (0.49-1.16) in Chinese, P-value=0.94, OR (95% CI)=0.97 (0.49-1.95) in Indian; For G/G vs. A/A: P-value=0.46, OR (95% CI)=1.14 (0.81-1.60) in pooled sample, P-value=0.80, OR (95% CI)=1.71 (0.94-3.10) in Malay, P-value=0.22, OR (95% CI)=0.71 (0.42-1.22) in Chinese; P-value=0.09, OR (95% CI)=1.89 (0.91-3.92) in India; For G/G vs. A/G +A/A: P-value=0.99, OR (95% CI)=1.27 (0.96-1.70) in pooled sample, P-value=0.02, OR (95% CI)=1.86 (1.12-3.10) in Malay, P-value=0.48, OR (95% CI)=0.85 (0.53-1.35) in Chinese; P-value=0.02, OR (95% CI)=1.92 (1.10-3.37) in Indian; For A/G + G/G vs. A/A: P-value=0.56, OR (95% CI)=0.92 (0.70-1.21) in pooled sample, P-value=0.75, OR (95% CI)=1.08 (0.68-1.73) in Malay, P-value=0.15, OR (95% CI)=0.74 (0.49-1.11) in Chinese, P-value=0.43, OR (95% CI)=1.29 (0.68-2.46) in Indian More... It provided no indication of any existing association betwe...... It provided no indication of any existing association between genotype distributions for both SNPs with bipolar disorder and schizophrenia in pooled individuals. The results showed a significant association using the recessive model for the rs7690296 polymorphism with schizophrenia in Malays and Indians, and a trend toward significance for the allelic model of the polymorphism was observed. More... Positive Zain, M. A., 2013
rs2371276 ERBB4 1(0/0/1) 1
Chi square test: allele P-value = 0.47, OR=1.066;genotype P...... Chi square test: allele P-value = 0.47, OR=1.066;genotype P-value = 0.763, chi square=0.541 for SCZ More... No significant association was observed. No significant association was observed. Negative Chen, P.,2012
rs7769372 MDGA1 1(0/0/1) 1
Single SNP analyses:allele, P-value = 0.9717, OR[95%CI]=1.0...... Single SNP analyses:allele, P-value = 0.9717, OR[95%CI]=1.0023[0.8829, 1.1378], genotype, P-value = 0.5694 for SZ More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(a)
rs2981578 FGFR2 1(0/0/1) 1
Allelic association results:P-value = 0.905, Permutated P-v...... Allelic association results:P-value = 0.905, Permutated P-value = 1 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Wang, T.,2012
rs7928347 GRIK4 1(0/0/1) 1
P-value = 0.279 between SCZ cases and controls; P-value = 0...... P-value = 0.279 between SCZ cases and controls; P-value = 0.382 between all cases and controls More... Negative Pickard, B. S., 2006
rs7107287 ARNTL 1(1/0/0) 1
not analyzed for Pittsburgh SZ/SZA not analyzed for Pittsburgh SZ/SZA Negative Mansour, H. A., 2006
rs1315158 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.0161 Alelle association:P-value = 0.0161 Significant association was observed Significant association was observed Positive Pickard, B. S.,2009
rs1455773 ST8SIA2 C15orf32 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs10883757 TRIM8 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.03991 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.03991 for BD and SCZ||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.04 for BD and SZ, Z-score=3.046 for SZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. This SNP is with conjunction FDR<0.08 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs4668331 GAD1 1(0/0/1) 1
Fisher's exact test:for SZ, in Scottish sample set, P-value...... Fisher's exact test:for SZ, in Scottish sample set, P-value(allele)=1, P-value(genotype)=0.92 More... No significant association was observed. No significant association was observed. Negative Lundorf, M. D.,2005
rs10091429 NRG1 1(0/0/1) 1
Individual P-value = 0.5259 for SCZ , Individual P-value = ...... Individual P-value = 0.5259 for SCZ , Individual P-value = 0.9077 for SCZ and BP More... Negative Thomson, P. A., 2007
rs2252865 RERE 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000476, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000476, FDR=0.377, FDR=0.03 for SCZ and BD||Conditional FDR; BD loci given SCZ: FDR=0.01306 for BD and SCZ||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.03 for BD and SZ, Z-score=3.494 for SZ More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.05. This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. This SNP is with conjunction FDR<0.05 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs12476147 ZNF804A 1(0/0/1) 1
P-value=0.053, X2=3.75, P-value = 0.026, one tai...... P-value=0.053, X2=3.75, P-value = 0.026, one tailed More... The minor A allele of the rs12476147 SNP, located in the ex...... The minor A allele of the rs12476147 SNP, located in the exon 4 of the ZNF804A gene, showed association with an increased risk of SZ (p = 0.026, one tailed) using DFAM.. More... Negative Guella, I., 2013
rs137932 MOV10L1 MLC1 1(0/0/1) 1
P-value = 0.7615 in SZ, P-value = 0.6327 in BD and SZ P-value = 0.7615 in SZ, P-value = 0.6327 in BD and SZ Negative Severinsen, J. E., 2006 (b)
rs231779 CTLA4 1(1/0/0) 1
For SZ:allele, OR[95%CI]=1.2676[1.1135-1.4429], P-value = 0...... For SZ:allele, OR[95%CI]=1.2676[1.1135-1.4429], P-value = 0.0003, P-permutation=0.001;genotype, P-value = 0.0016, P-permutation=0.0145 More... Significant association was found . Significant association was found . Positive Liu, J,2011(a)
rs5746832 TBX1 GNB1L 1(1/0/0) 1
For SZ, chi square test:allele P-value = 0.1371 For SZ, chi square test:allele P-value = 0.1371 No significant association was observed. No significant association was observed. Negative Li, Y.,2011
rs7175812 SLCO3A1 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs1094653 DISC1 TSNAX 1(0/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.45 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs7678609 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs3094228 HCP5 1(0/0/1) 1
logistic regression:for SZ full sample, OR=1.31, P-value = ...... logistic regression:for SZ full sample, OR=1.31, P-value = 5.96E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs4687657 ITIH4 MUSTN1 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000156, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000156, FDR=0.229, FDR=0.028 for SCZ and BD||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.028 for BD and SZ, Z-score=3.781 for SZ More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.22. This SNP is with conjunction FDR<0.09 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs1541187 BCL9 1(0/0/1) 1
Third-Stage Sample:for SZ, allele association P-value = 0.1...... Third-Stage Sample:for SZ, allele association P-value = 0.15, OR(95%CI)=1.16(0.95-1.43);Combined Third-Stage Sample, allele association P-value = 0.24, OR(98%CI)=1.06(0.97-1.17) More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(b)
rs17645023 CACNG5 1(0/1/0) 1
chi suqare test:SZ v.BP, P-value = E-6.2;SZ v.C, P-value = ...... chi suqare test:SZ v.BP, P-value = E-6.2;SZ v.C, P-value = E-2.1 More... Suggestive association was found. Suggestive association was found. Trend Curtis, D.,2011
rs17101921 FGFR2 1(0/0/1) 1
Allelic association results:P-value = 0.315, Permutated P-v...... Allelic association results:P-value = 0.315, Permutated P-value = 0.977 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Wang, T.,2012
rs11568171 MOV10L1 MLC1 1(1/0/0) 1
Case-control association:for SCZ, Fisher exact test, allele...... Case-control association:for SCZ, Fisher exact test, allele P-value > 0.05; chi-square test, genotype P-value(additive)>0.05, P-value(dominant)>0.05, P-value(recessive)>0.05 ;Family-Based Association:for SCZ, TDT, P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(b)
rs7158891 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.1112 Alelle association:P-value = 0.1112 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2189015 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 0.996(0.88–1.13),allelic...... Association analysis:OR(95%CI) = 0.996(0.88–1.13),allelic P-value = 0.942,genotypic P-value = 0.326 More... No significant association was found. No significant association was found. Negative Li, T.,2013
rs175174 ZDHHC8 1(0/0/1) 1
Chi-square test:for schizophrenia, genotype P-value = 0.46,...... Chi-square test:for schizophrenia, genotype P-value = 0.46, allele P-value = 0.28;for paranoid type, genotype P-value = 0.8, allele P-value = 0.57;for disorganized type, genotype P-value = 0.8, allele P-value = 0.96;for female schizophrenia, genotype P-value = 0.15, allele P-value = 0.38;for male schizophrenia, genotype P-value = 0.86, allele P-value = 0.75 More... No significant associations were found. No significant associations were found. Negative Otani, K.,2005(b)
rs2596565 ZDHHC20P2 HLA-S MICA 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00000933, FDR...... Conditional FDR; SCZ loci given BD: P-value=0.00000933, FDR=0.077, FDR=0.009 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs1948098 NRG1 1(0/0/1) 1
Individual P-value = 0.3353 for SCZ , Individual P-value = ...... Individual P-value = 0.3353 for SCZ , Individual P-value = 0.3572 for SCZ and BP More... Negative Thomson, P. A., 2007
rs278865 NR4A2 1(0/0/1) 1
Omnibus GWAS Test:P-value = 0.0000246, best-fit model is Sc...... Omnibus GWAS Test:P-value = 0.0000246, best-fit model is Schizophrenia specific More... Suggestive association was found. Suggestive association was found. Trend Huang, J.,2010
rs135745 CSNK1E 1(0/0/1) 1
Chi square test:MAF = 0.26,P-value = 0.12,OR = 1.12;P-value...... Chi square test:MAF = 0.26,P-value = 0.12,OR = 1.12;P-value = 0.095,OR = 1.26in meta analysis More... No significant association was observed. No significant association was observed. Negative Matsunaga, S.,2012
rs1424003 CDH11 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.01641 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.01641 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs4298458 NRG1 1(0/0/1) 1
Individual P-value = 0.6152 for SCZ , Individual P-value = ...... Individual P-value = 0.6152 for SCZ , Individual P-value = 0.9032 for SCZ and BP More... Negative Thomson, P. A., 2007
rs7872515 SPTLC1 RORA 1(0/0/1) 1
logistic regression:for SZ full sample, OR=0.73, P-value = ...... logistic regression:for SZ full sample, OR=0.73, P-value = 6.65E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs10774037 CACNA1C 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.00161 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.00161 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs1705233 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs1958035 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.2229 Alelle association:P-value = 0.2229 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs12668157 AKR1D1 1(0/0/1) 1
Single marker association:ALLELIC Model, chi square=4.67, d...... Single marker association:ALLELIC Model, chi square=4.67, df=1, P-value = 0.031;TREND Model, chi square=4.67, df=1, P-value = 0.031;DOM Model, chi square=3.85, df=1, P-value = 0.05 More... Significant association was found. Significant association was found. Positive Steen, N. E.,2010
rs961196 TTC7B 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00307, FDR=0....... Conditional FDR; SCZ loci given BD: P-value=0.00307, FDR=0.662, FDR=0.044 for SCZ and BD||Conditional FDR; BD loci given SCZ: FDR=0.01872 for BD and SCZ||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.044 for BD and SZ, Z-score=2.96 for SZ More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.63. This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. This SNP is with conjunction FDR<0.14 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs1801117 CSF2RB 1(0/0/1) 1
Single site association analysis:for SZ, allele, OR=0.978, ...... Single site association analysis:for SZ, allele, OR=0.978, P-value = 0.862 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Chen, P.,2011
rs4128599 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.7502 Alelle association:P-value = 0.7502 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs4908699 PER3 UTS2 1(0/0/1) 1
TDT P-value = 0.352, Trends test=0.161 for Pittsburgh SZ/SZ...... TDT P-value = 0.352, Trends test=0.161 for Pittsburgh SZ/SZA More... Negative Mansour, H. A., 2006
rs704076 DUSP6 1(1/0/0) 1
chi-square P-value = 0.6096, Permutation P-value = 0.9485, ...... chi-square P-value = 0.6096, Permutation P-value = 0.9485, X2=0.2607, OR=1.205; chi-square P-value = 0.4105, Permutation P-value = 0.8111, X2=0.6775, OR=1.648 for female subjects, chi-square P-value = 0.8973, Permutation P-value = 1, X2=0.0167, OR=0.9427 for male subjects More... showed nominally significant allelic associations with BD, ...... showed nominally significant allelic associations with BD, but not with SPR, in female patients More... Negative Kim, S. H., 2012 (a)
rs3918341 DAOA DAOA-AS1 1(0/0/1) 1
Fisher P-value = 0.5966 for all, P-value = 0.5966 for SCZ O...... Fisher P-value = 0.5966 for all, P-value = 0.5966 for SCZ Only More... Negative Detera-Wadleigh, S. D., 2006
rs11875674 TXNL1 1(0/1/0) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs2981427 FGFR2 1(0/0/1) 1
Allelic association results:P-value = 0.008, Permutated P-v...... Allelic association results:P-value = 0.008, Permutated P-value = 0.089 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Wang, T.,2012
rs1165678 HSP90B1 1(0/0/1) 1
chi-square genotypic P-value = 0.6356, allelic P-value = 0....... chi-square genotypic P-value = 0.6356, allelic P-value = 0.5415 for SZ cases in total samples More... No significant association was observed in single SNPs. How...... No significant association was observed in single SNPs. However, the result should be treated with caution, because there was a significant difference of gender between patients with schizophrenia and controls. More... Negative Kakiuchi, C., 2007 (a)
rs652888 EHMT2 SLC44A4 EHMT2-AS1 1(0/0/1) 1
logistic regression:for SZ full sample, OR=1.29, P-value = ...... logistic regression:for SZ full sample, OR=1.29, P-value = 7.28E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs4582985 GRIK4 1(0/0/1) 1
P-value = 0.842 between SCZ cases and controls; P-value = 0...... P-value = 0.842 between SCZ cases and controls; P-value = 0.621 between all cases and controls More... Negative Pickard, B. S., 2006
rs17662626 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000779, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000779, FDR=0.161, FDR=0.03 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.18. More... Positive Andreassen OA, 2013
rs7111184 GRIK4 1(0/0/1) 1
P-value = 0.821 between SCZ cases and controls; P-value = 0...... P-value = 0.821 between SCZ cases and controls; P-value = 0.736 between all cases and controls More... Negative Pickard, B. S., 2006
rs138881 BRD1 1(0/0/1) 1
P-value = 0.2896 in SZ, P-value = 0.1727 in BD and SZ P-value = 0.2896 in SZ, P-value = 0.1727 in BD and SZ Negative Severinsen, J. E., 2006 (b)
rs6589846 GRIK4 1(0/0/1) 1
P-value = 0.004 between SCZ cases and controls; P-value = 0...... P-value = 0.004 between SCZ cases and controls; P-value = 0.141 between all cases and controls More... showed significant association with schizophrenia showed significant association with schizophrenia Positive Pickard, B. S., 2006
rs11208776 PDE4B 1(1/0/0) 1
LD-proxy of rs11208776 (rs1937450): genotype test: P-value ...... LD-proxy of rs11208776 (rs1937450): genotype test: P-value = 0.046 in females, allele test: P-value = 0.032 and OR=1.23(1.02-1.49) in females, P-value = 0.067 and OR=1.26 in Demark females, OR=1.29 in Normay females, OR=1.11 in Sweden females. More... LD-proxy of rs11208776 (rs1937450) is nominally associated ...... LD-proxy of rs11208776 (rs1937450) is nominally associated with SZ in females. More... Positive Kahler, A. K., 2010
rs2439300 NRG1 1(0/0/1) 1
Individual P-value = 0.4052 for SCZ , Individual P-value = ...... Individual P-value = 0.4052 for SCZ , Individual P-value = 0.9469 for SCZ and BP More... Negative Thomson, P. A., 2007
rs2075984 CSNK1E 1(0/0/1) 1
Chi square test:MAF = 0.43,P-value = 0.0091,OR = 0.85;MAF =...... Chi square test:MAF = 0.43,P-value = 0.0091,OR = 0.85;MAF = 0.45,P-value = 0.63,OR = 0.98 in replication;P-value = 0.21,OR = 0.92in meta analysis More... The SNP showed a significant association with SZ. The SNP showed a significant association with SZ. Positive Matsunaga, S.,2012
rs1873827 YWHAE 1(1/0/0) 1
For SZ:allele, OR[95%CI]=0.89[0.79-1.01], P-value = 0.06768...... For SZ:allele, OR[95%CI]=0.89[0.79-1.01], P-value = 0.06768, P-permutation=0.5678;genotype, P-value = 0.1856, P-permutation=0.913 More... No significant association was observed. No significant association was observed. Negative Liu, J,2011(b)
rs17075286 POMGNT2 1(0/1/0) 1
chi suqare test:SZ v.BP, P-value = E-6.1;SZ v.C, P-value = ...... chi suqare test:SZ v.BP, P-value = E-6.1;SZ v.C, P-value = E-5.9 More... Suggestive association was found. Suggestive association was found. Trend Curtis, D.,2011
rs9346146 1(0/0/1) 1
logistic regression:for SZ new sample, OR=1.24, P-value = 9...... logistic regression:for SZ new sample, OR=1.24, P-value = 9.78E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs2284031 CSF2RB 1(0/0/1) 1
Single site association analysis:for SZ, allele, OR=0.813, ...... Single site association analysis:for SZ, allele, OR=0.813, P-value = 0.005 More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Chen, P.,2011
rs3795432 ZCCHC17 FABP3 1(0/0/1) 1
allele test P-value = 0.2038, genotype test P-value = 0.439...... allele test P-value = 0.2038, genotype test P-value = 0.4391 More... None of the 8 SNPs showed association with schizophrenia. None of the 8 SNPs showed association with schizophrenia. Negative Iwayama, Y., 2010
rs11130874 PTPRG 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00000945, FDR...... Conditional FDR; SCZ loci given BD: P-value=0.00000945, FDR=0.077, FDR=0.03 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.23. More... Positive Andreassen OA, 2013
rs17126243 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000129, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000129, FDR=0.08, FDR=0.027 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs17746001 1(0/0/1) 1
logistic regression:P-value > E-05 logistic regression:P-value > E-05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs17137124 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 0.946(0.83–1.08),allelic...... Association analysis:OR(95%CI) = 0.946(0.83–1.08),allelic P-value = 0.402,genotypic P-value = 0.552 More... No significant association was found. No significant association was found. Negative Li, T.,2013
rs6435387 KIF5C 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000428, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000428, FDR=0.115, FDR=0.02 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.16. More... Positive Andreassen OA, 2013
rs1625579 MIR137HG 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00000376, FDR...... Conditional FDR; SCZ loci given BD: P-value=0.00000376, FDR=0.065, FDR=0.011 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.10. More... Positive Andreassen OA, 2013
rs4982029 NPAS3 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs2272843 MOV10L1 1(0/0/1) 1
P-value = 0.2701 in SZ, P-value = 0.3018 in BD and SZ P-value = 0.2701 in SZ, P-value = 0.3018 in BD and SZ Negative Severinsen, J. E., 2006 (b)
rs11863156 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.00865 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.00865 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs363272 SLC18A2 1(0/0/1) 1
chi-square genotypic P-value = 0.038 for SZ, P-value = 0.13...... chi-square genotypic P-value = 0.038 for SZ, P-value = 0.133 for BD and SZ; chi-square allelic P-value = 0.177 for SZ, P-value = 0.169 for BD and SZ; 2-tailed Fisher's P-value = 0.024 for homozygous 745G variant More... a significant association between schizophrenia and A745G p...... a significant association between schizophrenia and A745G polymorphism was found; homozygous for the 745G variant were more frequent among the group of schizophrenic patients than among controls More... Positive Gutierrez, B., 2007
rs4775413 CYCSP38 1(0/0/1) 1
First-set screening: P-valuecorrected=0.65, P-va...... First-set screening: P-valuecorrected=0.65, P-value=0.0156, OR=1.18, 95%CI=1.03-1.34 More... Significant association was observed. Significant association was observed. Positive Saito T., 2014
rs1612902 KLK8 1(1/0/0) 1
Genotype frequency (df=2) X2=2.25, P value=0.32....... Genotype frequency (df=2) X2=2.25, P value=0.32. Allele frequency (df=1) X2=2.13, P value=0.14 in Patients with SZ vs controls. More... There was no significant difference in genotype or allele d...... There was no significant difference in genotype or allele distribution for any SNP between patients and controls for schizophrenia or major depression. More... Negative Izumi, A., 2008
rs3130893 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00000383, FDR...... Conditional FDR; SCZ loci given BD: P-value=0.00000383, FDR=0.065, FDR=0.006 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.31. More... Positive Andreassen OA, 2013
rs4949526 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000111, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000111, FDR=0.181, FDR=0.035 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.07. More... Positive Andreassen OA, 2013
rs4583255 TMEM219 TAOK2 1(0/0/1) 1
Association results in schizophrenia follow-up samples(10,6...... Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.06 (1.02, 1.10),P-value = 0.0011 More... No significant association was observed. No significant association was observed. Negative Steinberg, S.,2012
rs1475067 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.5028 Alelle association:P-value = 0.5028 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs11568176 MLC1 1(0/0/1) 1
Case-control association:for SCZ, Fisher exact test, allele...... Case-control association:for SCZ, Fisher exact test, allele P-value > 0.05; chi-square test, genotype P-value(additive)>0.05, P-value(dominant)>0.05, P-value(recessive)>0.05 ;Family-Based Association:for SCZ, TDT, P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(b)
rs1957317 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.6973 Alelle association:P-value = 0.6973 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs9969232 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 0.859(0.68–1.08),allelic...... Association analysis:OR(95%CI) = 0.859(0.68–1.08),allelic P-value = 0.2,genotypic P-value = 0.136 More... No significant association was found. No significant association was found. Negative Li, T.,2013
rs1545961 NRG1 1(0/0/1) 1
Individual P-value = 0.3823 for SCZ , Individual P-value = ...... Individual P-value = 0.3823 for SCZ , Individual P-value = 0.1336 for SCZ and BP More... Negative Thomson, P. A., 2007
rs7065696 PHF8 1(0/1/0) 1
chi suqare test:SZ v.BP, P-value = E-6.4;SZ v.C, P-value = ...... chi suqare test:SZ v.BP, P-value = E-6.4;SZ v.C, P-value = E-4.6 More... Suggestive association was found. Suggestive association was found. Trend Curtis, D.,2011
rs1800359 ZNF276 FANCA 1(1/0/0) 1
Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.035 ...... Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.035 for BD and SZ, Z-score=3.165 for SZ More... This SNP is with conjunction FDR<0.16 with schizophrenia an...... This SNP is with conjunction FDR<0.16 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs132234 FAM19A5 1(0/0/1) 1
P-value = 0.7013 in SZ, P-value = 0.6116 in BD and SZ P-value = 0.7013 in SZ, P-value = 0.6116 in BD and SZ Negative Severinsen, J. E., 2006 (b)
rs4760908 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs4821565 CSF2RB 1(0/0/1) 1
Single site association analysis:for SZ, allele, OR=1.035, ...... Single site association analysis:for SZ, allele, OR=1.035, P-value = 0.579 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Chen, P.,2011
rs948028 GRIK4 1(0/0/1) 1
P-value = 0.504 between SCZ cases and controls; P-value = 0...... P-value = 0.504 between SCZ cases and controls; P-value = 0.687 between all cases and controls More... Negative Pickard, B. S., 2006
rs710193 ST13 1(0/0/1) 1
CLUMP T1 P-value = 0.7065, CLUMP T4 P-value = 0.7065 for SZ...... CLUMP T1 P-value = 0.7065, CLUMP T4 P-value = 0.7065 for SZ; CLUMP T1 P-value = 0.7631, CLUMP T4 P-value = 0.7631 for BPD and SZ in the Faeroese Sample; Empirical overall P-value = 0.2758 for SZ in the Case-Control Sample From Scotland; Empirical overall P-value = 0.2317 for BPD and SZ in the Case-Control Sample From Scotland More... Negative Severinsen, J. E., 2006 (a)
rs5770755 ZBED4 1(0/0/1) 1
P-value = 0.72, OR=1.04 in UK/DK sample P-value = 0.72, OR=1.04 in UK/DK sample Nominal significant association with SZ Nominal significant association with SZ Positive Nyegaard, M., 2010
rs1958057 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.9441 Alelle association:P-value = 0.9441 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs6960610 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 0.945(0.83–1.07),allelic...... Association analysis:OR(95%CI) = 0.945(0.83–1.07),allelic P-value = 0.377,genotypic P-value = 0.0336 More... Significant association was observed . Significant association was observed . Positive Li, T.,2013
rs137936 MOV10L1 MLC1 1(0/0/1) 1
chi-square tests, P-value > 0.05 chi-square tests, P-value > 0.05 No association with the combined patient sample, SCZ or typ...... No association with the combined patient sample, SCZ or type A or type B schizophrenia was found. More... Negative Selch, S., 2007
rs927328 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.3943 Alelle association:P-value = 0.3943 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs1958059 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.3416 Alelle association:P-value = 0.3416 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs4430518 GRIK4 1(0/0/1) 1
P-value = 0.015 between SCZ cases and controls; P-value = 0...... P-value = 0.015 between SCZ cases and controls; P-value = 0.244 between all cases and controls More... showed significant association with schizophrenia showed significant association with schizophrenia Positive Pickard, B. S., 2006
rs12441404 ST8SIA2 C15orf32 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs1952162 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.3565 Alelle association:P-value = 0.3565 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs113317778 NRG1 1(1/0/0) 1
Several allelic associations were found in the entire pool ...... Several allelic associations were found in the entire pool of BD, but not in schizophrenia. More... Negative Gutierrez-Fernandez, A., 2014
rs2244291 USP46 1(0/0/1) 1
Allele-/genotype wise analyses:X2 test, allele P...... Allele-/genotype wise analyses:X2 test, allele P-value > 0.05;genotype P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Kushima, I.,2010
rs2303377 NCAM1 1(1/0/0) 1
Fisher's exact test, allelic P-value = 0.24 in SZ; Fisher's...... Fisher's exact test, allelic P-value = 0.24 in SZ; Fisher's exact test, allelic P-value = 0.264 in BD&SZ More... SNP b was not associated with SZ. SNP b was not associated with SZ. Negative Atz, M. E., 2007
rs4821888 SYNGR1 1(0/0/1) 1
Fisher's exact test:allele P-value = 0.7, chi-square test:g...... Fisher's exact test:allele P-value = 0.7, chi-square test:genotype P-value = 0.9 in SCZ More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(a)
rs11205362 PRPF3 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00111, FDR=0....... Conditional FDR; SCZ loci given BD: P-value=0.00111, FDR=0.489, FDR=0.033 for SCZ and BD||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.033 for BD and SZ, Z-score=3.262 for SZ More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.11. This SNP is with conjunction FDR<0.07 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs1240083 BCL9 1(0/0/1) 1
Third-Stage Sample:for SZ, allele association P-value = 0.0...... Third-Stage Sample:for SZ, allele association P-value = 0.09, OR(95%CI)=0.87(0.74-1.02);Combined Third-Stage Sample, allele association P-value = 0.000152, OR(98%CI)=0.86(0.79-0.93) More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(b)
rs10995315 EGR2 1(1/0/0) 1
For SZ, chi-square tests:allele, OR=1.116, X2=0....... For SZ, chi-square tests:allele, OR=1.116, X2=0.3138, P-value = 0.5754, P-value(permutation)=0.99;Fisher's exact test, genotype, X2=2.8926, P-value = 0.2354 More... No significant association was observed. No significant association was observed. Negative Kim, S. H.,2011
rs3911862 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.04864 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.04864 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs1480380 HLA-DMA HLA-DMB 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000106, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000106, FDR=0.077, FDR=0.01 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs2284178 HCP5 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000331, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000331, FDR=0.316, FDR=0.036 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs9462341 MDGA1 1(0/0/1) 1
Single SNP analyses:allele, P-value = 0.0267(0.3417), OR[95...... Single SNP analyses:allele, P-value = 0.0267(0.3417), OR[95%CI]=0.8684[0.7665, 0.9838], genotype, P-value = 0.0196(0.2666 after permutations) for SZ More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(a)
rs7126303 ARNTL RN7SKP151 1(1/0/0) 1
Single SNP-based analyses:Trends test P-value = 0.738 in SZ Single SNP-based analyses:Trends test P-value = 0.738 in SZ No significant association was observed No significant association was observed Negative Mansour, H. A.,2009
rs6001566 SYNGR1 1(0/0/1) 1
Fisher's exact test:allele P-value = 0.025, chi-square test...... Fisher's exact test:allele P-value = 0.025, chi-square test:genotype P-value = 0.1 in SCZ More... Significant association was observed in allelic association...... Significant association was observed in allelic association. More... Positive Verma, R.,2005(a)
rs5748427 TBX1 GNB1L 1(1/0/0) 1
For SZ, chi square test:allele P-value = 0.0011 For SZ, chi square test:allele P-value = 0.0011 Significant association was observed in SZ. Significant association was observed in SZ. Positive Li, Y.,2011
rs3016384 OPCML 1(0/0/1) 1
X2 tests:allele P-value = 0.85 for SCZ. X2 tests:allele P-value = 0.85 for SCZ. No significant association was observed. No significant association was observed. Negative Schanze, D.,2011
rs2077841 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.7985 Alelle association:P-value = 0.7985 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs1722550 KLK8 KLK9 1(1/0/0) 1
Genotype frequency (df=2) X2=1.97, P value=0.37....... Genotype frequency (df=2) X2=1.97, P value=0.37. Allele frequency (df=1) X2=0.62, P value=0.43 in Patients with SZ vs controls. More... There was no significant difference in genotype or allele d...... There was no significant difference in genotype or allele distribution for any SNP between patients and controls for schizophrenia or major depression. More... Negative Izumi, A., 2008
rs999710 DISC1 TSNAX 1(0/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.47 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs2236570 BCL9 1(0/0/1) 1
Third-Stage Sample:for SZ, allele association P-value = 0.7...... Third-Stage Sample:for SZ, allele association P-value = 0.7, OR(95%CI)=0.97(0.85-1.11);Combined Third-Stage Sample, allele association P-value = 0.88, OR(98%CI)=1.00(0.93-1.06) More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(b)
rs2290035 BTBD10 ARNTL 1(0/0/1) 1
TDT P-value = 0.935, Trends test=0.689 for Pittsburgh SZ/SZ...... TDT P-value = 0.935, Trends test=0.689 for Pittsburgh SZ/SZA More... Negative Mansour, H. A., 2006
rs3786284 IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.267, genotypic P-v...... Fisher's exact test, allelic P-value = 0.267, genotypic P-value = 0.521 More... Negative Ohnishi, T., 2007
rs1030711 TSNAX DISC1 1(1/0/0) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.91 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs2012906 SYNGR1 1(0/0/1) 1
Fisher's exact test:allele P-value = 0.9, chi-square test:g...... Fisher's exact test:allele P-value = 0.9, chi-square test:genotype P-value = 0.4 in SCZ More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(a)
rs8064578 YWHAE 1(0/0/1) 1
For SZ:allele, OR[95%CI]=1[0.89-1.13], P-value = 0.97582, P...... For SZ:allele, OR[95%CI]=1[0.89-1.13], P-value = 0.97582, P-permutation=1;genotype, P-value = 0.40742, P-permutation=0.9983 More... No significant association was observed. No significant association was observed. Negative Liu, J,2011(b)
rs6554557 USP46 1(0/0/1) 1
Allele-/genotype wise analyses:X2 test, allele P...... Allele-/genotype wise analyses:X2 test, allele P-value > 0.05;genotype P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Kushima, I.,2010
rs11150863 RPTOR NPTX1 1(0/0/1) 1
logistic regression:for SZ new sample, OR=0.78, P-value = 3...... logistic regression:for SZ new sample, OR=0.78, P-value = 3.49E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs871167 SLCO3A1 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs1736913 HLA-F-AS1 HLA-F 1(1/0/0) 1
First-set screening: P-valuecorrected=0.89, P-va...... First-set screening: P-valuecorrected=0.89, P-value=0.0212, OR=1.19, 95%CI=1.03-1.39; Second-set replication: P-valuecorrected=0.0866, P-value=0.0433, OR=1.11, 95%CI=1.00-1.23. Current study (first-set screening_second-set replication): P-value=0.00800, I2=0.0; PGC+current study: P-value=0.00445, I2=59.7 More... Significant association was observed. Significant association was observed. Positive Saito T., 2014
rs960914 FZD3 MIR4288 1(0/0/1) 1
Allelic association:P-value = 0.91 for SZ Allelic association:P-value = 0.91 for SZ No significant association was observed in SZ. No significant association was observed in SZ. Negative Hashimoto, R.,2005(b)
rs127503 OSTM1 OSTM1-AS1 NR2E1 1(0/0/1) 1
X2=0.51, OR (95% CI)=0.93 (0.93-1.15), P-value =...... X2=0.51, OR (95% CI)=0.93 (0.93-1.15), P-value = 0.475 for SZ. More... No association was detected with schizophrenia. No association was detected with schizophrenia. Negative Kumar, R. A., 2008
rs1203847 RNF4 1(0/1/0) 1
chi suqare test:SZ v.BP, P-value = E-5;SZ v.C, P-value = E-...... chi suqare test:SZ v.BP, P-value = E-5;SZ v.C, P-value = E-6.9 More... Suggestive association was found. Suggestive association was found. Trend Curtis, D.,2011
rs1554338 CRY2 MAPK8IP1 1(1/0/0) 1
Single SNP-based analyses:Trends test P-value = 0.411 in SZ Single SNP-based analyses:Trends test P-value = 0.411 in SZ No significant association was observed No significant association was observed Negative Mansour, H. A.,2009
rs770087 DUSP6 1(1/0/0) 1
chi-square P-value = 0.9919, Permutation P-value = 1, X chi-square P-value = 0.9919, Permutation P-value = 1, X2=0.0001, OR=0.9961; chi-square P-value = 0.4652, Permutation P-value = 0.8983, X2=0.5333, OR=1.559 for female subjects, chi-square P-value = 0.4958, Permutation P-value = 0.9196, X2=0.464, OR=0.7172 for male subjects More... showed nominally significant allelic associations with BD, ...... showed nominally significant allelic associations with BD, but not with SPR, in female patients More... Negative Kim, S. H., 2012 (a)
rs2233488 OSTM1 NR2E1 1(0/0/1) 1
X2=0.81, OR (95% CI)=1.27 (0.74-2.19), P-value =...... X2=0.81, OR (95% CI)=1.27 (0.74-2.19), P-value = 0.367 for SZ. More... No association was detected with schizophrenia. No association was detected with schizophrenia. Negative Kumar, R. A., 2008
rs989713 MDGA1 1(0/0/1) 1
Single SNP analyses:allele, P-value = 0.2801, OR[95%CI]=1.1...... Single SNP analyses:allele, P-value = 0.2801, OR[95%CI]=1.1064[0.9209, 1.3294], genotype, P-value = 0.0969 for SZ More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(a)
rs1060041 DCAF6 1(0/0/1) 1
First-set screening: P-valuecorrected=1, P-value...... First-set screening: P-valuecorrected=1, P-value=0.0481, OR=1.21, 95%CI=1.00-1.46 More... Significant association was observed. Significant association was observed. Positive Saito T., 2014
rs2853884 YWHAH 1(0/0/1) 1
LRT P-value:0.43(Psychotic features), 0.38(Mood-incongruent...... LRT P-value:0.43(Psychotic features), 0.38(Mood-incongruent psychotic features) More... None of the SNPs showed any difference between observed and...... None of the SNPs showed any difference between observed and expected allelic transmissionswhen the mood-incongruent psychotic BP phenotype was used.And none of the SNPs were impacted by the moodincongruence covariate. More... Negative Grover, D.,2009
rs2072707 CSF2RB 1(0/0/1) 1
Single site association analysis:for SZ, allele, OR=0.926, ...... Single site association analysis:for SZ, allele, OR=0.926, P-value = 0.417 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Chen, P.,2011
rs949054 GRIK4 1(0/0/1) 1
P-value = 0.894 between SCZ cases and controls; P-value = 0...... P-value = 0.894 between SCZ cases and controls; P-value = 0.509 between all cases and controls More... Negative Pickard, B. S., 2006
rs2120753 1(0/0/1) 1
Fisher’s exact test, P-value=8.7E-05, OR (95% CI)=0.60 (0...... Fisher’s exact test, P-value=8.7E-05, OR (95% CI)=0.60 (0.46-0.78), FDR=0.179 in all cases of the case-contro sample; P-value=0.18, OR (95% CI)=0.80 (0.58-1.11) in all families of the kindred sample; P-value=2.5E-04, OR (95% CI)=0.68 (0.56-0.84) for the combined analyses; P-value=0.074, OR (95% CI)=0.65 (0.41-1.04) in SZ families of the kindred sample; P-value=1.1E-05, OR (95% CI)=0.63 (0.51-0 .77) for the combined analyses; P-value=0.18, OR (95% CI)=0.80 (0.58, 1.11) More... No association of this SNP was replicated. No association of this SNP was replicated. Negative Bureau A, 2013
rs3732062 SLC1A4 1(0/0/1) 1
no P-value no P-value Allele and haplotype frequencies did not differ between cas...... Allele and haplotype frequencies did not differ between cases and controls. More... Negative Skowronek, M. H., 2006
rs7759855 ZSCAN31 1(1/0/0) 1
First-set screening: P-valuecorrected=0.12, P-va...... First-set screening: P-valuecorrected=0.12, P-value=0.00292, OR=1.48, 95%CI=1.14-1.91; Second-set replication: P-valuecorrected=0.0322, P-value=0.0161, OR=1.23, 95%CI=1.04-1.46. Current study (first-set screening_second-set replication): P-value=6.65*10-4, I2=25.4; PGC+current study: P-value=5.02*10-4, I2=0.0. More... Significant association was observed. Significant association was observed. Positive Saito T., 2014
rs1170099 DGKH 1(0/0/1) 1
Allelic association:P-value = 0.0005, permutated P-value = ...... Allelic association:P-value = 0.0005, permutated P-value = 0.005 for SCZ More... Significant association was found. Significant association was found. Positive Zeng, Z.,2011
rs956884 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.0635 Alelle association:P-value = 0.0635 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs4517638 DAOA 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000011, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000011, FDR=0.077, FDR=0.015 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs704073 DUSP6 1(1/0/0) 1
chi-square P-value = 0.5978, Permutation P-value = 0.9424, ...... chi-square P-value = 0.5978, Permutation P-value = 0.9424, X2=0.2783, OR=1.294; chi-square P-value = 0.6115, Permutation P-value = 0.9859, X2=0.2579, OR=1.475 for female subjects, chi-square P-value = 0.8272, Permutation P-value = 0.9993, X2=0.0476, OR=1.149 for male subjects More... showed nominally significant allelic associations with BD, ...... showed nominally significant allelic associations with BD, but not with SPR, in female patients More... Negative Kim, S. H., 2012 (a)
rs1440201 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.6785 Alelle association:P-value = 0.6785 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs4907103 LPAR3 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000977, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000977, FDR=0.181, FDR=0.039 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.09. More... Positive Andreassen OA, 2013
rs2153522 ANK3 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000792, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000792, FDR=0.449, FDR=0.046 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs3766512 BCL9 ACP6 1(0/0/1) 1
Third-Stage Sample:for SZ, allele association P-value = 0.2...... Third-Stage Sample:for SZ, allele association P-value = 0.23, OR(95%CI)=1.08(0.95-1.22);Combined Third-Stage Sample, allele association P-value = 0.01, OR(98%CI)=1.08(1.02-1.15) More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Li, J.,2011(b)
rs138841 BRD1 1(0/0/1) 1
P-value = 0.46, OR=1.08 in UK/DK sample P-value = 0.46, OR=1.08 in UK/DK sample Nominal significant association with SZ Nominal significant association with SZ Positive Nyegaard, M., 2010
rs7007662 NRG1 NRG1-IT1 1(0/0/1) 1
Individual P-value = 0.7023 for SCZ , Individual P-value = ...... Individual P-value = 0.7023 for SCZ , Individual P-value = 0.7981 for SCZ and BP More... Negative Thomson, P. A., 2007
rs2239670 CARTPT 1(0/0/1) 1
Chi-square test genotypic P-value = 0.350, allelic P-value ...... Chi-square test genotypic P-value = 0.350, allelic P-value = 0.364, OR (95% CI)=1.139 (0.859-2.512) for schizophrenia when compared with controls. More... The AvaII polymorphism of the CART gene did not show associ...... The AvaII polymorphism of the CART gene did not show association with schizophrenia. More... Negative Jung, S. K., 2004
rs7925270 GRIK4 1(0/0/1) 1
P-value = 0.859 between SCZ cases and controls; P-value = 0...... P-value = 0.859 between SCZ cases and controls; P-value = 0.695 between all cases and controls More... Negative Pickard, B. S., 2006
rs4820902 OSBP2 1(0/0/1) 1
logistic regression:for SZ new sample, OR=0.78, P-value = 9...... logistic regression:for SZ new sample, OR=0.78, P-value = 9.98E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs7225165 YWHAE 1(0/0/1) 1
For SZ:allele, OR[95%CI]=1.01[0.82-1.241], P-value = 0.9163...... For SZ:allele, OR[95%CI]=1.01[0.82-1.241], P-value = 0.91631, P-permutation=1;genotype, P-value = 0.02739, P-permutation=0.3011 More... Significant association was found, but the significance was...... Significant association was found, but the significance was lost after permutation. More... Positive Liu, J,2011(b)
rs4305746 TAAR6 1(0/0/1) 1
Allele frequency (SZ vs.control) 0.38 vs. 0.45; X2 Allele frequency (SZ vs.control) 0.38 vs. 0.45; X2(df=1)= 6.28, P-value = 0.019 More... The minor allele (A) of the adjoining SNP, rs7452939, was u...... The minor allele (A) of the adjoining SNP, rs7452939, was under-represented in the schizophrenia group, but this comparison did not survive Bonferroni correction. More... Positive Pae, C. U., 2008
rs3217293 FEZ1 1(0/0/1) 1
Association analysis:Fisher's exact test, allele P-value = ...... Association analysis:Fisher's exact test, allele P-value = 0.867, genotype P-value = 0.555 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Yamada, K.,2004
rs9566940 DGKH 1(0/0/1) 1
Allelic association:P-value = 0.281, permutated P-value = 0...... Allelic association:P-value = 0.281, permutated P-value = 0.941 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs12998068 GALNT13 1(0/0/1) 1
logistic regression:for SZ new sample, OR=1.4, P-value = 1....... logistic regression:for SZ new sample, OR=1.4, P-value = 1.50E-06, for SZ full sample, OR=1.32, P-value = 8.60E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs676318 LRP5 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000141, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000141, FDR=0.08, FDR=0.023 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs1279214 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.7657 Alelle association:P-value = 0.7657 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2269726 GNB1L 1(1/0/0) 1
For SZ, chi square test:allele P-value = 0.0078 For SZ, chi square test:allele P-value = 0.0078 Significant association was observed in SZ. Significant association was observed in SZ. Positive Li, Y.,2011
rs821633 DISC1 1(1/0/0) 1
(CC+CT)>TT:for SZ, P-value > 0.05 (CC+CT)>TT:for SZ, P-value > 0.05 No significant association was observed. No significant association was observed. Negative Chakirova, G.,2011
rs6496898 SLCO3A1 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs821470 NLRC5 1(0/0/1) 1
logistic regression:for SZ new sample, OR=1.28, P-value = 9...... logistic regression:for SZ new sample, OR=1.28, P-value = 9.83E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs1156026 1(1/0/0) 1
Fisher’s exact test, P-value=4.4E-06, OR (95% CI)=1.81 (1...... Fisher’s exact test, P-value=4.4E-06, OR (95% CI)=1.81 (1.39, 2.35), FDR=0.014 in all cases of the case-contro sample; P-value=0.012, OR (95% CI)=1.54 (1.1, 2.17) in all families of the kindred sample; P-value=8.5E-07, OR (95% CI)=1.69 (1.37, 2.08) for the combined analyses; P-value=8.8E-04, OR (95% CI)=2.03 (1.34, 3.09) in SZ families of the kindred sample; P-value=6.4E-08, OR (95% CI)=1.85 (1.48, 2.31) for the combined analyses; P-value=0.012, OR (95% CI)=1.54 (1.1, 2.17) More... An association of the T allele of rs1156026 found in the ca...... An association of the T allele of rs1156026 found in the case-control sample was replicated in the kindred sample, strengthening the overall association evidence. More... Positive Bureau A, 2013
rs3949783 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.4938 Alelle association:P-value = 0.4938 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2799573 CACNB2 1(1/0/0) 1
Association analysis:P-value = 0.0000000429,OR(95%CI) = 1.0...... Association analysis:P-value = 0.0000000429,OR(95%CI) = 1.08(1.05-1.12) when five disorders were combined More... Significant association was observed in cross-disorder anal...... Significant association was observed in cross-disorder analysis. More... Positive Cross-Disorder Group of the Psychiatric Genomics Consortium,2013
rs2400546 PAWR 1(0/0/1) 1
Hardy-Weinberg equilibrium P value=0.106, genotypic P value...... Hardy-Weinberg equilibrium P value=0.106, genotypic P value=0.786, allelic P value=0.474 for schizophrenia compared with controls. More... No association was detected with schizophrenia or MDD in al...... No association was detected with schizophrenia or MDD in allele/genotype-wise analyses. More... Negative Kishi, T., 2008 (a)
rs7787274 MAD1L1 FTSJ2 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000327, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000327, FDR=0.316, FDR=0.028 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs9886497 NRG1 1(0/0/1) 1
Individual P-value = 0.2086 for SCZ , Individual P-value = ...... Individual P-value = 0.2086 for SCZ , Individual P-value = 0.2653 for SCZ and BP More... Negative Thomson, P. A., 2007
rs726908 NRG1 1(0/0/1) 1
Individual P-value = 0.6665 for SCZ , Individual P-value = ...... Individual P-value = 0.6665 for SCZ , Individual P-value = 0.5578 for SCZ and BP More... Negative Thomson, P. A., 2007
rs707284 ERBB4 1(0/0/1) 1
Chi square test: allele P-value = 0.22, OR=1.08;genotype P-...... Chi square test: allele P-value = 0.22, OR=1.08;genotype P-value = 0.343, chi square=2.139 for SCZ More... No significant association was observed. No significant association was observed. Negative Chen, P.,2012
rs1279210 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.972 Alelle association:P-value = 0.972 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs55909231 KLK8 KLK9 1(0/0/1) 1
Genotype frequency (df=2) X2=0.21, P value=0.90....... Genotype frequency (df=2) X2=0.21, P value=0.90. Allele frequency (df=1) X2=0.11, P value=0.74 in Patients with SZ vs controls. More... There was no significant difference in genotype or allele d...... There was no significant difference in genotype or allele distribution for any SNP between patients and controls for schizophrenia or major depression. More... Negative Izumi, A., 2008
rs11931061 CLOCK 1(0/0/1) 1
chi-square test: 1. total samples:P-value = 0.536(Genotype)...... chi-square test: 1. total samples:P-value = 0.536(Genotype), P-value = 0.699(Allele) in SCZ 2. male samples: P-value = 0.561(Genotype) 3. female samples: P-value = 0.159(Genotype), P-value = 0.24(Allele) in SCZ More... We did not find an association between these tag SNPs and J...... We did not find an association between these tag SNPs and Japanese schizophrenia, BP or MDD in any of the analyses. More... Negative Kishi, T.,2009(a)
rs1124910 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.1914 Alelle association:P-value = 0.1914 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs10508451 CCDC3 OPTN 1(0/1/0) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs2270586 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 0.035 More... Significant association was found. Significant association was found. Positive Scholz, C. J.,2010
rs2187495 GRIK4 1(0/0/1) 1
P-value = 0.864 between SCZ cases and controls; P-value = 0...... P-value = 0.864 between SCZ cases and controls; P-value = 0.357 between all cases and controls More... Negative Pickard, B. S., 2006
rs4271171 FAM20B 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs17487223 CHRNB4 1(1/0/0) 1
P-value=0.03, OR=1.08, 95% CI=(0.98-1.14) in SZD; P-value=0...... P-value=0.03, OR=1.08, 95% CI=(0.98-1.14) in SZD; P-value=0.009, OR=1.07, 95% CI=(1.02-1.13) in SZD + BD; P-value=0.018, OR=1.21, 95% CI=(1.06-1.43) in SZD with the presence of negative symptoms of schizophrenia More... Two variants, rs8040868 and rs17487223, were significantly ...... Two variants, rs8040868 and rs17487223, were significantly associated with risk for schizophrenia. When the schizophrenia and bipolar disorder results were combined, four markers, rs951266, rs16969968, rs8040868, and rs17487223, were significantly associated with risk for schizophrenia and bipolar disorder. A meta-analysis of the results revealed a significant association with the variants rs951266, rs1051730, rs8040868, and rs1748722, and the presence of negative symptoms. More... Positive Jackson, K. J., 2013
rs917815 SP8 1(0/1/0) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs7071307 PPP2R2D 1(0/1/0) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs808820 DUSP6 1(1/0/0) 1
chi-square P-value = 0.9126, Permutation P-value = 0.9994, ...... chi-square P-value = 0.9126, Permutation P-value = 0.9994, X2=0.0121, OR=1.047; chi-square P-value = 0.4866, Permutation P-value = 0.9137, X2=0.4841, OR=1.595 for female subjects, chi-square P-value = 0.6207, Permutation P-value = 0.9726, X2=0.2448, OR=0.7687 for male subjects More... showed nominally significant allelic associations with BD, ...... showed nominally significant allelic associations with BD, but not with SPR, in female patients More... Negative Kim, S. H., 2012 (a)
rs1701947 KLK8 KLK9 1(0/0/1) 1
Genotype frequency (df=2) X2=4.86, P value=0.09....... Genotype frequency (df=2) X2=4.86, P value=0.09. Allele frequency (df=1) X2=2.15, P value=0.14 in Patients with SZ vs controls. More... There was no significant difference in genotype or allele d...... There was no significant difference in genotype or allele distribution for any SNP between patients and controls for schizophrenia or major depression. More... Negative Izumi, A., 2008
rs10189138 VRK2 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000142, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000142, FDR=0.229, FDR=0.038 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.14. More... Positive Andreassen OA, 2013
rs9990 EGR2 ADO 1(0/0/1) 1
For SZ, chi-square tests:allele, OR=1.244, X2=3....... For SZ, chi-square tests:allele, OR=1.244, X2=3.3587, P-value = 0.0668, P-value(permutation)=0.305;Fisher's exact test, genotype, X2=5.4069, P-value = 0.067 More... No significant association was observed. No significant association was observed. Negative Kim, S. H.,2011
rs11237798 TENM4 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs3757440 MAD1L1 FTSJ2 1(1/0/0) 1
Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.031 ...... Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.031 for BD and SZ, Z-score=3.425 for SZ More... This SNP is with conjunction FDR<0.11 with schizophrenia an...... This SNP is with conjunction FDR<0.11 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs879602 GRIK4 1(0/0/1) 1
P-value = 0.677 between SCZ cases and controls; P-value = 0...... P-value = 0.677 between SCZ cases and controls; P-value = 0.936 between all cases and controls More... Negative Pickard, B. S., 2006
rs2117975 GPR176 EIF2AK4 1(0/0/1) 1
Omnibus GWAS Test:P-value = 0.000037, best-fit model is Sch...... Omnibus GWAS Test:P-value = 0.000037, best-fit model is Schizophrenia specific More... Suggestive association was found. Suggestive association was found. Trend Huang, J.,2010
rs2981581 FGFR2 1(0/0/1) 1
Allelic association results:P-value = 0.409, Permutated P-v...... Allelic association results:P-value = 0.409, Permutated P-value = 0.995 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Wang, T.,2012
rs10261327 SP4 1(0/0/1) 1
Allelic association:Chinese Trios for Schizophrenia:TDT:Ris...... Allelic association:Chinese Trios for Schizophrenia:TDT:Risk allele is C, MAF=0.471P-value = 0.908 More... No significant association was observed No significant association was observed Negative Zhou, X.,2009
rs2010904 SYNGR1 1(1/0/0) 1
Fisher's exact test:allele P-value = 0.5, chi-square test:g...... Fisher's exact test:allele P-value = 0.5, chi-square test:genotype P-value = 0.9 in SCZ More... No significant association was observed. No significant association was observed. Negative Verma, R.,2005(a)
rs243310 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.1094 Alelle association:P-value = 0.1094 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs1602565 1(0/0/1) 1
X2 tests:allele P-value = 0.87 for SCZ. X2 tests:allele P-value = 0.87 for SCZ. No significant association was observed. No significant association was observed. Negative Schanze, D.,2011
rs6466488 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 0.956(0.84–1.08),allelic...... Association analysis:OR(95%CI) = 0.956(0.84–1.08),allelic P-value = 0.469,genotypic P-value = 0.657 More... No significant association was found. No significant association was found. Negative Li, T.,2013
rs12543276 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000138, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000138, FDR=0.203, FDR=0.046 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs9897526 GRN FAM171A2 1(0/0/1) 1
Association analysis:chi square test, genotype P-value > 0....... Association analysis:chi square test, genotype P-value > 0.05;allele P-value > 0.05 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Galimberti, D.,2012
rs9268862 HLA-DRB9 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000000621, FD...... Conditional FDR; SCZ loci given BD: P-value=0.000000621, FDR=0.037, FDR=0.002 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs1952603 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.7234 Alelle association:P-value = 0.7234 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs1025526 LINC00582 TSNAX DISC1 1(0/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.86 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs7383287 HLA-DOB 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000271, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000271, FDR=0.095, FDR=0.019 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs997650 PIP4K2A 1(0/0/1) 1
ARMITAGE P-value = 0.813 for Schizophrenia ARMITAGE P-value = 0.813 for Schizophrenia In the single marker analysis, none of the analyzed variant...... In the single marker analysis, none of the analyzed variants revealed significant association to disease status, neither for schizophrenia nor for BPAD. More... Negative Jamra, R. A., 2006 (a)
rs6009917 ZBED4 1(0/0/1) 1
P-value = 0.1, OR=2.93 in UK/DK sample P-value = 0.1, OR=2.93 in UK/DK sample Nominal significant association with SZ Nominal significant association with SZ Positive Nyegaard, M., 2010
rs6001093 CSNK1E 1(0/0/1) 1
Chi square test:MAF = 0.08,P-value = 0.18,OR = 0.86 Chi square test:MAF = 0.08,P-value = 0.18,OR = 0.86 No significant association was observed. No significant association was observed. Negative Matsunaga, S.,2012
rs2235698 GABBR1 1(0/0/1) 1
logistic regression:for SZ full sample, OR=0.8, P-value = 8...... logistic regression:for SZ full sample, OR=0.8, P-value = 8.59E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs7141245 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.5923 Alelle association:P-value = 0.5923 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs11655548 YWHAE 1(0/0/1) 1
For SZ:allele, OR[95%CI]=0.94[0.83-1.07], P-value = 0.33275...... For SZ:allele, OR[95%CI]=0.94[0.83-1.07], P-value = 0.33275, P-permutation=0.9925;genotype, P-value = 0.53898, P-permutation=1 More... No significant association was observed. No significant association was observed. Negative Liu, J,2011(b)
rs12452627 YWHAE 1(0/0/1) 1
For SZ:allele, OR[95%CI]=1[0.82-1.22], P-value = 0.99501, P...... For SZ:allele, OR[95%CI]=1[0.82-1.22], P-value = 0.99501, P-permutation=1;genotype, P-value = 0.02701, P-permutation=0.0702 More... Significant association was found, but the significance was...... Significant association was found, but the significance was lost after permutation. More... Positive Liu, J,2011(b)
rs173383 NPAS3 1(1/0/0) 1
Alelle association:P-value = 0.2477 Alelle association:P-value = 0.2477 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs28757218 OTX2 1(1/0/0) 1
no P-value given no P-value given the rate did not differ significantly from that observed in...... the rate did not differ significantly from that observed in the control population More... Negative Sabunciyan, S., 2007
rs910799 ZBED4 1(0/0/1) 1
P-value = 0.8, OR=0.97 in UK/DK sample P-value = 0.8, OR=0.97 in UK/DK sample Nominal significant association with SZ Nominal significant association with SZ Positive Nyegaard, M., 2010
rs9567552 BRCA2 ZAR1L 1(1/0/0) 1
CMH test:P-value = 0.52, OR (95% CI)=1.05(0.91-1.20) for SC...... CMH test:P-value = 0.52, OR (95% CI)=1.05(0.91-1.20) for SCZ. More... No significant association was observed. No significant association was observed. Negative Tesli, M.,2010
rs3786291 IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.903, genotypic P-v...... Fisher's exact test, allelic P-value = 0.903, genotypic P-value = 0.922 More... Negative Ohnishi, T., 2007
rs6543004 NPAS2 1(0/0/1) 1
Single SNP-based analyses:Trends test P-value = 0.024 in SZ Single SNP-based analyses:Trends test P-value = 0.024 in SZ Significant association was observed Significant association was observed Positive Mansour, H. A.,2009
rs10034164 USP46 1(0/0/1) 1
Allele-/genotype wise analyses:X2 test, allele P...... Allele-/genotype wise analyses:X2 test, allele P-value > 0.05;genotype P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Kushima, I.,2010
rs12539410 PLXNA4 CHCHD3 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs4757142 ARNTL 1(1/0/0) 1
not analyzed for Pittsburgh SZ/SZA not analyzed for Pittsburgh SZ/SZA Negative Mansour, H. A., 2006
rs3916970 DAOA-AS1 DAOA 1(0/0/1) 1
Fisher P-value = 0.5966 for all, P-value = 0.5966 for SCZ O...... Fisher P-value = 0.5966 for all, P-value = 0.5966 for SCZ Only More... Negative Detera-Wadleigh, S. D., 2006
rs2852217 GRIK4 1(0/0/1) 1
P-value = 0.405 between SCZ cases and controls; P-value = 0...... P-value = 0.405 between SCZ cases and controls; P-value = 0.175 between all cases and controls More... Negative Pickard, B. S., 2006
rs1078163 NTRK3 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000267, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000267, FDR=0.095, FDR=0.017 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs1795648 ERC2 1(0/1/0) 1
chi suqare test:SZ v.BP, P-value = E-5.2;SZ v.C, P-value = ...... chi suqare test:SZ v.BP, P-value = E-5.2;SZ v.C, P-value = E-1.3 More... Suggestive association was found. Suggestive association was found. Trend Curtis, D.,2011
rs6591348 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000116, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000116, FDR=0.08, FDR=0.027 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs11199993 FGFR2 1(1/0/0) 1
Allelic association results:P-value = 0.088, Permutated P-v...... Allelic association results:P-value = 0.088, Permutated P-value = 0.608 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Wang, T.,2012
rs912857 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.4742 Alelle association:P-value = 0.4742 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs7521783 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.02503 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.02503 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs2000869 GRIK4 1(0/0/1) 1
P-value = 0.984 between SCZ cases and controls; P-value = 0...... P-value = 0.984 between SCZ cases and controls; P-value = 0.677 between all cases and controls More... Negative Pickard, B. S., 2006
rs149729514 GRIN3A 1(0/0/1) 1
P-value=0.00042, OR=1.58 P-value=0.00042, OR=1.58 The GRIN3A R480G variant (rs149729514) was most significant...... The GRIN3A R480G variant (rs149729514) was most significantly associated with schizophrenia. More... Positive Takata, A., 2013
rs1409497 SACS SGCG 1(0/0/1) 1
logistic regression:for SZ full sample, OR=1.39, P-value = ...... logistic regression:for SZ full sample, OR=1.39, P-value = 5.17E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs10103750 NRG1 1(0/0/1) 1
Individual P-value = 0.2753 for SCZ , Individual P-value = ...... Individual P-value = 0.2753 for SCZ , Individual P-value = 0.6566 for SCZ and BP More... Negative Thomson, P. A., 2007
rs10096770 NRG1 1(0/0/1) 1
Individual P-value = 0.9176 for SCZ , Individual P-value = ...... Individual P-value = 0.9176 for SCZ , Individual P-value = 0.5636 for SCZ and BP More... Negative Thomson, P. A., 2007
rs12708772 SHISA9 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00312, FDR=0....... Conditional FDR; SCZ loci given BD: P-value=0.00312, FDR=0.662, FDR=0.044 for SCZ and BD||Conditional FDR; BD loci given SCZ: FDR=0.04219 for BD and SCZ||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.044 for BD and SZ, Z-score=2.955 for SZ More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.63. This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. This SNP is with conjunction FDR<0.14 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs3135730 FGFR2 1(0/0/1) 1
Allelic association results:P-value = 0.765, Permutated P-v...... Allelic association results:P-value = 0.765, Permutated P-value = 1 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Wang, T.,2012
rs10761482 ANK3 1(1/0/0) 1
Genotype association:CC P-value = 0.593, CT P-value = 0.196...... Genotype association:CC P-value = 0.593, CT P-value = 0.196, TT P-value = 0.113 for SZ. More... No significant association was observed. No significant association was observed. Negative Gella, A.,2011
rs8004477 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.5017 Alelle association:P-value = 0.5017 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs907094 PPP1R1B STARD3 1(1/0/0) 1
Genotypic P-value = 0.518, Armitage's P-value = 0.673. alle...... Genotypic P-value = 0.518, Armitage's P-value = 0.673. allelic P-value = 0.681 in SZ. More... Single-marker in a sample set showed that PPP1R1B polymorph...... Single-marker in a sample set showed that PPP1R1B polymorphisms were not significantly associated with schizophrenia. More... Negative Yoshimi, A., 2008
rs2301558 TBX1 1(0/0/1) 1
X2= 0.046, P-value = 0.830 for schizophrenia wh...... X2= 0.046, P-value = 0.830 for schizophrenia when compared with controls. More... None of the nine individual SNPs showed a positive associat...... None of the nine individual SNPs showed a positive association in the 'all affecteds' category. More... Negative Funke, B. H., 2007
rs3758354 ANXA1 1(0/1/0) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs9901910 CSNK1D SLC16A3 1(0/0/1) 1
Chi square test:MAF = 0.26,P-value = 0.48,OR = 0.95 Chi square test:MAF = 0.26,P-value = 0.48,OR = 0.95 No significant association was observed. No significant association was observed. Negative Matsunaga, S.,2012
rs198829 HIST1H2BC 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000218, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000218, FDR=0.088, FDR=0.027 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.27. More... Positive Andreassen OA, 2013
rs949056 GRIK4 1(0/0/1) 1
P-value = 0.87 between SCZ cases and controls; P-value = 0....... P-value = 0.87 between SCZ cases and controls; P-value = 0.476 between all cases and controls More... Negative Pickard, B. S., 2006
rs701158 DISC1 DISC1-IT1 TSNAX 1(0/0/1) 1
Single-Marker Analysis:allele frequency, for SZ, P-value = ...... Single-Marker Analysis:allele frequency, for SZ, P-value = 0.68 More... No significant association was observed. No significant association was observed. Negative Thomson, P. A.,2005(a)
rs17691363 RORB 1(1/0/0) 1
Single SNP-based analyses:Trends test P-value = 0.983 in SZ Single SNP-based analyses:Trends test P-value = 0.983 in SZ No significant association was observed No significant association was observed Negative Mansour, H. A.,2009
rs8014172 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.7115 Alelle association:P-value = 0.7115 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs4309482 TCF7L2 1(0/0/1) 1
Association results in schizophrenia follow-up samples(10,6...... Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.08 (1.04, 1.12),P-value = 1.7 x 10-5 More... No significant association was observed. No significant association was observed. Negative Steinberg, S.,2012
rs13213152 ZSCAN12 1(0/0/1) 1
logistic regression:for SZ full sample, OR=1.42, P-value = ...... logistic regression:for SZ full sample, OR=1.42, P-value = 8.43E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs9411508 LCN1P2 SURF6 1(0/0/1) 1
logistic regression:for SZ full sample, OR=0.49, P-value = ...... logistic regression:for SZ full sample, OR=0.49, P-value = 8.59E-06 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs1468089 GNB1L 1(0/0/1) 1
For SZ, chi square test:allele P-value = 0.1219 For SZ, chi square test:allele P-value = 0.1219 No significant association was observed. No significant association was observed. Negative Li, Y.,2011
rs2383420 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.1203 Alelle association:P-value = 0.1203 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs248797 SRD5A1 1(1/0/0) 1
Single marker association:ALLELIC Model, chi square=4.16, d...... Single marker association:ALLELIC Model, chi square=4.16, df=1, P-value = 0.041;TREND Model, chi square=3.97, df=1, P-value = 0.046 More... Significant association was found. Significant association was found. Positive Steen, N. E.,2010
rs6311 HTR2A 1(0/0/1) 1
Meta analysis: Allele model:Asian,OR = 0.9,95%CI = 0.80–1...... Meta analysis: Allele model:Asian,OR = 0.9,95%CI = 0.80–1.01; Caucasian,OR = 1.12,95%CI = 1.05–1.20; Total,OR = 1.06,95%CI = 1.00–1.12.Dominant model:Asian,OR = 0.91,95%CI = 0.76–1.08; Caucasian,OR = 1.14,95%CI = 1.03–1.27; Total,OR = 1.07,95%CI = 0.98–1.18.Recessive model:Asian,OR = 0.83,95%CI = 0.68–1.01; Caucasian,OR = 1.2,95%CI = 1.06–1.37; Total,OR = 1.08,95%CI = 0.97–1.20.Codominant model1:Asian,OR = 0.84,95%CI = 0.68–1.04; Caucasian,OR = 1.16,95%CI = 1.01–1.32; Total,OR = 1.06,95%CI = 0.94–1.19.Codominant model2:Asian,OR = 0.96,95%CI = 0.79–1.15; Caucasian,OR = 1.1,95%CI = 0.99–1.23; Total,OR = 1.06,95%CI = 0.97–1.17. More... Our results showed that the -1438A/G polymorphism was a ris...... Our results showed that the -1438A/G polymorphism was a risk factor for SZ, especially in Caucasians. More... Positive Gu, L.,2013
rs4733140 NRG1 1(0/0/1) 1
Individual P-value = 0.6035 for SCZ , Individual P-value = ...... Individual P-value = 0.6035 for SCZ , Individual P-value = 0.8239 for SCZ and BP More... Negative Thomson, P. A., 2007
rs943164 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.3802 Alelle association:P-value = 0.3802 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2293618 HSP90B1 C12orf73 1(0/0/1) 1
chi-square genotypic P-value = 0.1446, allelic P-value = 0....... chi-square genotypic P-value = 0.1446, allelic P-value = 0.2683 for SZ cases in total samples More... No significant association was observed in single SNPs. How...... No significant association was observed in single SNPs. However, the result should be treated with caution, because there was a significant difference of gender between patients with schizophrenia and controls. More... Negative Kakiuchi, C., 2007 (a)
rs3794217 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs2035645 ST8SIA2 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs1563408 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 1.082(0.96–1.23),allelic...... Association analysis:OR(95%CI) = 1.082(0.96–1.23),allelic P-value = 0.216,genotypic P-value = 0.0142 More... Significant association was observed . Significant association was observed . Positive Li, T.,2013
rs2000959 SLC6A5 1(0/0/1) 1
data not shown data not shown In the single-marker analysis, none of the analyzed variant...... In the single-marker analysis, none of the analyzed variants revealed a significant association with disease. More... Negative Jamra, R. A., 2006 (b)
rs4390476 UBE2D3P4 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.03843 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.03843 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs1487141 NRG1 1(0/0/1) 1
Individual P-value = 0.9662 for SCZ , Individual P-value = ...... Individual P-value = 0.9662 for SCZ , Individual P-value = 0.8195 for SCZ and BP More... Negative Thomson, P. A., 2007
rs753239 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.5868 Alelle association:P-value = 0.5868 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2075825 IMPA2 1(1/0/0) 1
Fisher's exact test, allelic P-value = 1, genotypic P-value...... Fisher's exact test, allelic P-value = 1, genotypic P-value = 1 More... Negative Ohnishi, T., 2007
rs737868 TBX1 1(0/0/1) 1
X2= 2.561, P-value = 0.110 for schizophrenia wh...... X2= 2.561, P-value = 0.110 for schizophrenia when compared with controls. More... None of the nine individual SNPs showed a positive associat...... None of the nine individual SNPs showed a positive association in the 'all affecteds' category. More... Negative Funke, B. H., 2007
rs17180327 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000129, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000129, FDR=0.08, FDR=0.038 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.17. More... Positive Andreassen OA, 2013
rs2304634 DNAJA3 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000079, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000079, FDR=0.161, FDR=0.026 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs813592 GCKR FNDC4 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000271, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000271, FDR=0.095, FDR=0.014 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.13. More... Positive Andreassen OA, 2013
rs10494251 BCL9 1(0/0/1) 1
Third-Stage Sample:for SZ, allele association P-value = 0.5...... Third-Stage Sample:for SZ, allele association P-value = 0.53, OR(95%CI)=0.95(0.83-1.1);Combined Third-Stage Sample, allele association P-value = 0.02, OR(98%CI)=0.92(0.86-0.99) More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Li, J.,2011(b)
rs2907228 FEZ1 1(0/0/1) 1
Allelic P-value = 0.804, genotypic P-value = 0.259 in Cau...... Allelic P-value = 0.804, genotypic P-value = 0.259 in Caucasians. Allelic P-value = 0.848, genotypic P-value = 0.982 in African Americans. More... No association to schizophrenia was found for any of the ni...... No association to schizophrenia was found for any of the nine markers typed in these populations at the allelic or the genotypic level. More... Negative Hodgkinson, C. A., 2007
rs729217 NPAS3 1(1/0/0) 1
Alelle association:P-value = 0.089 Alelle association:P-value = 0.089 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2675968 C2orf82 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000564, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000564, FDR=0.143, FDR=0.021 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.19. More... Positive Andreassen OA, 2013
rs1365410 FEZ1 1(0/0/1) 1
Allelic P-value = 0.237 in Caucasians. Allelic P-value = ...... Allelic P-value = 0.237 in Caucasians. Allelic P-value = 0.576, genotypic P-value = 0.531 in African Americans. More... No association to schizophrenia was found for any of the ni...... No association to schizophrenia was found for any of the nine markers typed in these populations at the allelic or the genotypic level. More... Negative Hodgkinson, C. A., 2007
rs12458992 CCDC102B 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs13150700 SORBS2 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000277, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000277, FDR=0.286, FDR=0.048 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.25. More... Positive Andreassen OA, 2013
rs12778366 SIRT1 1(0/0/1) 1
For SZ, X2 test:genotype, X2(2df)=1.2...... For SZ, X2 test:genotype, X2(2df)=1.21, P-value = 0.545;allele, X2(2df)=0.555, P-value = 0.456 More... No significant association was observed. No significant association was observed. Negative Kishi, T.,2011(a)
rs8040868 CHRNA3 1(1/0/0) 1
P-value=0.004, OR=1.09, 95% CI=(1.03-1.16) in SZD; P-value=...... P-value=0.004, OR=1.09, 95% CI=(1.03-1.16) in SZD; P-value=0.007, OR=1.07, 95% CI=(1.02-1.12) in SZD + BD; P-value=0.02, OR=1.16, 95% CI=(1.02-1.31) in SZD with the presence of negative symptoms of schizophrenia More... Two variants, rs8040868 and rs17487223, were significantly ...... Two variants, rs8040868 and rs17487223, were significantly associated with risk for schizophrenia. When the schizophrenia and bipolar disorder results were combined, four markers, rs951266, rs16969968, rs8040868, and rs17487223, were significantly associated with risk for schizophrenia and bipolar disorder. A meta-analysis of the results revealed a significant association with the variants rs951266, rs1051730, rs8040868, and rs1748722, and the presence of negative symptoms. More... Positive Jackson, K. J., 2013
rs2122246 DGKH 1(1/0/0) 1
Allelic association:P-value = 0.069, permutated P-value = 0...... Allelic association:P-value = 0.069, permutated P-value = 0.472 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs1315141 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.5627 Alelle association:P-value = 0.5627 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs363387 SLC18A2 1(0/0/1) 1
chi-square genotypic P-value = 0.304 for SZ, P-value = 0.76...... chi-square genotypic P-value = 0.304 for SZ, P-value = 0.769 for BD and SZ; chi-square allelic P-value = 0.319 for SZ, P-value = 0.777 for BD and SZ More... associations with the polymorphism were not detected with t...... associations with the polymorphism were not detected with the schizophrenic group More... Negative Gutierrez, B., 2007
rs3763978 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 0.031 More... Significant association was found. Significant association was found. Positive Scholz, C. J.,2010
rs916005 MAPK8IP2 CHKB 1(0/0/1) 1
P-value = 0.8482 in SZ, P-value = 1 in BD and SZ P-value = 0.8482 in SZ, P-value = 1 in BD and SZ Negative Severinsen, J. E., 2006 (b)
rs716193 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.7973 Alelle association:P-value = 0.7973 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs135757 CSNK1E 1(0/0/1) 1
Chi square test:MAF = 0.22,P-value = 0.67,OR = 0.97 Chi square test:MAF = 0.22,P-value = 0.67,OR = 0.97 No significant association was observed. No significant association was observed. Negative Matsunaga, S.,2012
rs10997875 SIRT1 HERC4 1(0/0/1) 1
For SZ, X2 test:genotype, X2(2df)=2.8...... For SZ, X2 test:genotype, X2(2df)=2.84, P-value = 0.242;allele, X2(2df)=0.00002, P-value = 0.996 More... No significant association was observed. No significant association was observed. Negative Kishi, T.,2011(a)
rs3134942 NOTCH4 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.04844 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.04844 for BD and SCZ||Conjunction FDR; pleiotropic loci in SCZ and BD: FDR=0.048 for BD and SZ, Z-score=3.571 for SZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. This SNP is with conjunction FDR<0.08 with schizophrenia and bipolar disorder considered jointly. More... Positive Andreassen OA, 2013
rs872123 GAD1 1(1/0/0) 1
Fisher's exact test:for SZ, in Scottish sample set, P-value...... Fisher's exact test:for SZ, in Scottish sample set, P-value(allele)=0.51, P-value(genotype)=0.1 More... No significant association was observed. No significant association was observed. Negative Lundorf, M. D.,2005
rs839511 ERBB4 1(0/0/1) 1
Chi square test: allele P-value = 0.937, OR=0.992;genotype ...... Chi square test: allele P-value = 0.937, OR=0.992;genotype P-value = 0.932, chi square=0.14 for SCZ More... No significant association was observed. No significant association was observed. Negative Chen, P.,2012
rs559668 FEZ1 1(0/0/1) 1
Allelic P-value = 0.732, genotypic P-value = 0.927 in Cau...... Allelic P-value = 0.732, genotypic P-value = 0.927 in Caucasians. Allelic P-value = 0.411, genotypic P-value = 0.369 in African Americans. More... No association to schizophrenia was found for any of the ni...... No association to schizophrenia was found for any of the nine markers typed in these populations at the allelic or the genotypic level. More... Negative Hodgkinson, C. A., 2007
rs1886781 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.7734 Alelle association:P-value = 0.7734 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs748806 GNB1L 1(1/0/0) 1
For SZ, chi square test:allele P-value = 0.0001 For SZ, chi square test:allele P-value = 0.0001 Significant association was observed in SZ. Significant association was observed in SZ. Positive Li, Y.,2011
rs7152665 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.329 Alelle association:P-value = 0.329 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2144600 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.6363 Alelle association:P-value = 0.6363 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs12562824 FABP3 1(0/0/1) 1
allele test P-value = 0.8354, genotype test P-value = 0.688...... allele test P-value = 0.8354, genotype test P-value = 0.6886 More... None of the 8 SNPs showed association with schizophrenia. None of the 8 SNPs showed association with schizophrenia. Negative Iwayama, Y., 2010
rs739374 TBX1 1(0/0/1) 1
X2= 1.694, P-value = 0.193 for schizophrenia wh...... X2= 1.694, P-value = 0.193 for schizophrenia when compared with controls. More... None of the nine individual SNPs showed a positive associat...... None of the nine individual SNPs showed a positive association in the 'all affecteds' category. More... Negative Funke, B. H., 2007
rs17109370 TSPAN8 1(0/0/1) 1
Cochran-Armitage test (dominant model):Bonferroni-Corrected...... Cochran-Armitage test (dominant model):Bonferroni-Corrected P-value = 1 More... No significant association was observed. No significant association was observed. Negative Scholz, C. J.,2010
rs729231 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.5379 Alelle association:P-value = 0.5379 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2246704 YWHAH 1(1/0/0) 1
LRT P-value:0.02(Psychotic features), 0.30(Mood-incongruent...... LRT P-value:0.02(Psychotic features), 0.30(Mood-incongruent psychotic features) More... Using a family-based association test, we found that rs2246...... Using a family-based association test, we found that rs2246704 was associated with BP (OR=1.31, P=0.03) and psychotic BP (OR=1.66, P=0.002).None of the SNPs showed any difference between observed and expected allelic transmissionswhen the mood-incongruent psychotic BP phenotype was used.And none of the SNPs were impacted by the moodincongruence covariate. More... Positive Grover, D.,2009
rs10914367 FABP3 1(0/0/1) 1
allele test P-value = 0.7429, genotype test P-value = 0.622...... allele test P-value = 0.7429, genotype test P-value = 0.6223 More... None of the 8 SNPs showed association with schizophrenia. None of the 8 SNPs showed association with schizophrenia. Negative Iwayama, Y., 2010
rs4586379 ST8SIA2 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs4746720 SIRT1 HERC4 1(0/0/1) 1
For SZ, X2 test:genotype, X2(2df)=8.0...... For SZ, X2 test:genotype, X2(2df)=8.07, P-value = 0.0177, corrected P-value = 0.142;allele, X2(2df)=6.75, P-value = 0.00947, , corrected P-value = 0.0758 More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Kishi, T.,2011(a)
rs7895695 RRP12 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000357, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000357, FDR=0.115, FDR=0.018 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs4777760 RGMA 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs886424 LINC00243 1(0/0/1) 1
logistic regression:for SZ new sample, OR=0.71, P-value = 8...... logistic regression:for SZ new sample, OR=0.71, P-value = 8.80E-06, for SZ full sample, OR=0.68, P-value = 4.54E-08 More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Bergen, S. E.,2012
rs7192086 SHISA9 1(0/0/1) 1
X2 tests:allele P-value = 0.78 for SCZ. X2 tests:allele P-value = 0.78 for SCZ. No significant association was observed. No significant association was observed. Negative Schanze, D.,2011
rs11436 FABP3 ZCCHC17 1(0/0/1) 1
allele test P-value = 0.3073, genotype test P-value = 0.465...... allele test P-value = 0.3073, genotype test P-value = 0.4655 More... None of the 8 SNPs showed association with schizophrenia. None of the 8 SNPs showed association with schizophrenia. Negative Iwayama, Y., 2010
rs2439286 NRG1 1(0/0/1) 1
Individual P-value = 0.6369 for SCZ , Individual P-value = ...... Individual P-value = 0.6369 for SCZ , Individual P-value = 0.5518 for SCZ and BP More... Negative Thomson, P. A., 2007
rs1315151 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.4632 Alelle association:P-value = 0.4632 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs701492 GAD1 1(0/0/1) 1
Fisher's exact test:for SZ, in Scottish sample set, P-value...... Fisher's exact test:for SZ, in Scottish sample set, P-value(allele)=0.4, P-value(genotype)=0.66 More... No significant association was observed. No significant association was observed. Negative Lundorf, M. D.,2005
rs1456029 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 1.013(0.89–1.15),allelic...... Association analysis:OR(95%CI) = 1.013(0.89–1.15),allelic P-value = 0.836,genotypic P-value = 0.85 More... No significant association was found. No significant association was found. Negative Li, T.,2013
rs1953447 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.3017 Alelle association:P-value = 0.3017 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs11705394 CSF2RB 1(0/0/1) 1
Single site association analysis:for SZ, allele, OR=1.087, ...... Single site association analysis:for SZ, allele, OR=1.087, P-value = 0.525 More... No significant association was observed in SZ. No significant association was observed in SZ. Negative Chen, P.,2011
rs9462343 MDGA1 1(0/0/1) 1
Single SNP analyses:allele, P-value = 0.8462, OR[95%CI]=1.0...... Single SNP analyses:allele, P-value = 0.8462, OR[95%CI]=1.0172[0.8564, 1.2081], genotype, P-value = 0.1161 for SZ More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(a)
rs11759115 MDGA1 1(0/0/1) 1
Single SNP analyses:allele, P-value = 0.0131(0.1902), OR[95...... Single SNP analyses:allele, P-value = 0.0131(0.1902), OR[95%CI]=0.8055[0.6789, 0.9558], genotype, P-value = 0.0026(0.0086 after permutations) for SZ More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Li, J.,2011(a)
rs1952161 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.8259 Alelle association:P-value = 0.8259 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs9838229 CCDC39 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000289, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000289, FDR=0.104, FDR=0.045 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.24. More... Positive Andreassen OA, 2013
rs243021 BCL11A 1(1/0/0) 1
P-value=0.12, Pcorrected=1, OR=0.89 for SZ in screening sta...... P-value=0.12, Pcorrected=1, OR=0.89 for SZ in screening stage, P-value=0.59, OR=1.03 for replication. More... No association was found for SZ. No association was found for SZ. Negative Kajio, Y., 2014
rs3809646 VPS9D1 ZNF276 VPS9D1-AS1 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.03171 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.03171 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs3846881 MDGA1 1(0/0/1) 1
Single SNP analyses:allele, P-value = 0.5268, OR[95%CI]=1.0...... Single SNP analyses:allele, P-value = 0.5268, OR[95%CI]=1.0395[0.9220, 1.1721], genotype, P-value = 0.0758 for SZ More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(a)
rs573140 SIPA1L2 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.03009 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.03009 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs2254884 ABCA1 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000117, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000117, FDR=0.203, FDR=0.032 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs3823198 RPS6KA2 FAM103A2P 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.01779 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.01779 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs7972947 CACNA1C 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000000532, FD...... Conditional FDR; SCZ loci given BD: P-value=0.000000532, FDR=0.035, FDR=0.013 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs11939815 CLOCK 1(0/0/1) 1
chi-square test: 1.total samples: P-value = 0.513(Genotype)...... chi-square test: 1.total samples: P-value = 0.513(Genotype), P-value = 0.724(Allele) in SCZ 2. male samples: P-value = 0.510(Genotype), P-value = 0.754(Allele) in SCZ 3 female samples:P-value = 0.110(Genotype), P-value = 0.163(Allele) in SCZ More... We did not find an association between these tag SNPs and J...... We did not find an association between these tag SNPs and Japanese schizophrenia, BP or MDD in any of the analyses. More... Negative Kishi, T.,2009(a)
rs10495658 RN7SKP168 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000399, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000399, FDR=0.115, FDR=0.044 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.12. More... Positive Andreassen OA, 2013
rs719017 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.6093 Alelle association:P-value = 0.6093 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs347387 DGKH 1(1/0/0) 1
Allelic association:P-value = 0.404, permutated P-value = 0...... Allelic association:P-value = 0.404, permutated P-value = 0.989 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs727447 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.8735 Alelle association:P-value = 0.8735 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs4143873 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.39 Alelle association:P-value = 0.39 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2523722 TRIM26 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000000254, FD...... Conditional FDR; SCZ loci given BD: P-value=0.000000254, FDR=0.025, FDR=0.001 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs10275045 MAD1L1 1(0/0/1) 1
P-value=1.84E-06 for BP, P-value=5.53E-13 for BP+SZ, Het P-...... P-value=1.84E-06 for BP, P-value=5.53E-13 for BP+SZ, Het P-value=0.85 More... Most significant SNP in six genome-wide significant regions...... Most significant SNP in six genome-wide significant regions. More... Negative Ruderfer, D. M., 2013
rs11579756 KAZN 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000117, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000117, FDR=0.203, FDR=0.037 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.06. More... Positive Andreassen OA, 2013
rs11545506 IMPA2 1(0/0/1) 1
Fisher's exact test, allelic P-value = 0.882, genotypic P-v...... Fisher's exact test, allelic P-value = 0.882, genotypic P-value = 0.983 More... Negative Ohnishi, T., 2007
rs5758209 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00000506, FDR...... Conditional FDR; SCZ loci given BD: P-value=0.00000506, FDR=0.068, FDR=0.031 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs2372008 CRIM1 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs8018440 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.7945 Alelle association:P-value = 0.7945 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs805294 LY6G6C C6orf25 LY6G6D 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000111, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000111, FDR=0.181, FDR=0.039 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs11133385 CLOCK 1(0/0/1) 1
chi-square test: 1.total samples:P-value = 0.881(Genotype),...... chi-square test: 1.total samples:P-value = 0.881(Genotype), P-value = 0.541(Allele) in SCZ 2. male samples: P value=0.245(Genotype), P-value = 0.342(Allele) in SCZ 3. female samples: P-value = 0.248(Genotype), P-value = 0.527(Allele) in SCZ More... We did not find an association between these tag SNPs and J...... We did not find an association between these tag SNPs and Japanese schizophrenia, BP or MDD in any of the analyses. More... Negative Kishi, T.,2009(a)
rs688325 BCL9 1(0/0/1) 1
Third-Stage Sample:for SZ, allele association P-value = 0.0...... Third-Stage Sample:for SZ, allele association P-value = 0.006, OR(95%CI)=1.19(1.05-1.33);Combined Third-Stage Sample, allele association P-value = 0.000254, OR(98%CI)=1.11(1.05-1.18) More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Li, J.,2011(b)
rs10217594 RORB 1(1/0/0) 1
Single SNP-based analyses:Trends test P-value = 0.313 in SZ Single SNP-based analyses:Trends test P-value = 0.313 in SZ No significant association was observed No significant association was observed Negative Mansour, H. A.,2009
rs3810971 MOV10L1 1(0/0/1) 1
P-value = 0.3431 in SZ, P-value = 0.9874 in BD and SZ P-value = 0.3431 in SZ, P-value = 0.9874 in BD and SZ Negative Severinsen, J. E., 2006 (b)
rs4820059 C22orf24 YWHAH 1(1/0/0) 1
LRT P-value:0.03(Psychotic features), 0.76(Mood-incongruent...... LRT P-value:0.03(Psychotic features), 0.76(Mood-incongruent psychotic features) More... It had evidence of association with BP that was impacted by...... It had evidence of association with BP that was impacted by the psychotic features covariate. More... Positive Grover, D.,2009
rs13072940 TRANK1 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000127, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000127, FDR=0.08, FDR=0.013 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.21. More... Positive Andreassen OA, 2013
rs5748432 GNB1L 1(1/0/0) 1
For SZ, chi square test:allele P-value = 0.0011 For SZ, chi square test:allele P-value = 0.0011 Significant association was observed in SZ. Significant association was observed in SZ. Positive Li, Y.,2011
rs879606 PPP1R1B 1(0/0/1) 1
Genotypic P-value = 0.631, Armitage's P-value = 0.985. alle...... Genotypic P-value = 0.631, Armitage's P-value = 0.985. allelic P-value = 0.985 in SZ. More... Single-marker in a sample set showed that PPP1R1B polymorph...... Single-marker in a sample set showed that PPP1R1B polymorphisms were not significantly associated with schizophrenia. More... Negative Yoshimi, A., 2008
rs1958547 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.8893 Alelle association:P-value = 0.8893 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs7224258 YWHAE 1(0/0/1) 1
For SZ:allele, OR[95%CI]=0.92[0.83-1.07], P-value = 0.30125...... For SZ:allele, OR[95%CI]=0.92[0.83-1.07], P-value = 0.30125, P-permutation=0.9862;genotype, P-value = 0.27691, P-permutation=0.9789 More... No significant association was observed. No significant association was observed. Negative Liu, J,2011(b)
rs3802177 SLC30A8 1(1/0/0) 1
P-value=0.95, Pcorrected=1, OR=1.00 for SZ in screening sta...... P-value=0.95, Pcorrected=1, OR=1.00 for SZ in screening stage. More... No association was found for SZ. No association was found for SZ. Negative Kajio, Y., 2014
rs9566931 DGKH 1(0/0/1) 1
Allelic association:P-value = 0.874, permutated P-value = 1...... Allelic association:P-value = 0.874, permutated P-value = 1 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs1886782 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.3319 Alelle association:P-value = 0.3319 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2337506 CHRNA7 1(0/0/1) 1
Association analysis:allele P-value > 0.05, genotype P-valu...... Association analysis:allele P-value > 0.05, genotype P-value > 0.05 More... No significant association was observed. No significant association was observed. Negative Joo, E. J.,2010
rs2439305 NRG1 1(0/0/1) 1
Individual P-value = 0.6679 for SCZ , Individual P-value = ...... Individual P-value = 0.6679 for SCZ , Individual P-value = 0.752 for SCZ and BP More... Negative Thomson, P. A., 2007
rs502771 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000297, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000297, FDR=0.104, FDR=0.039 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs2186122 PDE4B 1(1/0/0) 1
LD-proxy of rs2186122 (rs3009872): genotype test: P-value =...... LD-proxy of rs2186122 (rs3009872): genotype test: P-value = 0.043 in females, allele test: P-value = 0.088 and OR=1.18 in females, OR=1.14 in Demark females, OR=1.35 in Normay females, OR=1.15 in Sweden females. More... LD-proxy of rs2186122 (rs3009872) is nominally associated w...... LD-proxy of rs2186122 (rs3009872) is nominally associated with SZ in females. More... Positive Kahler, A. K., 2010
rs30434 SRD5A1 1(0/0/1) 1
Single marker association:DOM Model, chi square=5.42, df=1,...... Single marker association:DOM Model, chi square=5.42, df=1, P-value = 0.02;ALLELIC Model, chi square=4.65, df=1, P-value = 0.031;TREND Model, chi square=4.26, df=1, P-value = 0.039 More... Significant association was found. Significant association was found. Positive Steen, N. E.,2010
rs3784735 ST8SIA2 1(1/0/0) 1
P-value > 0.075 P-value > 0.075 Single SNP analysis did not yield significant evidence for ...... Single SNP analysis did not yield significant evidence for association. More... Negative McAuley, E. Z., 2012
rs243291 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.159 Alelle association:P-value = 0.159 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs9532988 DGKH MAPK6PS3 1(0/0/1) 1
Allelic association:P-value = 0.282, permutated P-value = 0...... Allelic association:P-value = 0.282, permutated P-value = 0.942 for SCZ More... No significant association was observed after permutation. No significant association was observed after permutation. Negative Zeng, Z.,2011
rs5742909 CTLA4 1(0/0/1) 1
For SZ:allele, OR[95%CI]=0.9075[0.7595-1.0843], P-value = 0...... For SZ:allele, OR[95%CI]=0.9075[0.7595-1.0843], P-value = 0.2849, P-permutation=0.9128;genotype, P-value = 0.3861, P-permutation=0.9719 More... No significant association was observed. No significant association was observed. Negative Liu, J,2011(a)
rs943194 PIP4K2A 1(0/0/1) 1
ARMITAGE P-value = 0.064 for Schizophrenia ARMITAGE P-value = 0.064 for Schizophrenia In the single marker analysis, none of the analyzed variant...... In the single marker analysis, none of the analyzed variants revealed significant association to disease status, neither for schizophrenia nor for BPAD. More... Negative Jamra, R. A., 2006 (a)
rs7749823 HIST1H1E HIST1H2BD 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000000132, FD...... Conditional FDR; SCZ loci given BD: P-value=0.000000132, FDR=0.014, FDR=0.005 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.28. More... Positive Andreassen OA, 2013
rs28365859 YWHAE 1(0/0/1) 1
For SZ:allele, OR[95%CI]=1.04[0.91-1.19], P-value = 0.5431,...... For SZ:allele, OR[95%CI]=1.04[0.91-1.19], P-value = 0.5431, P-permutation=1;genotype, P-value = 0.18954, P-permutation=0.9176 More... No significant association was observed. No significant association was observed. Negative Liu, J,2011(b)
rs566202 SRD5A1 1(1/0/0) 1
Single marker association:P-value > 0.05 in all model. Single marker association:P-value > 0.05 in all model. No significant association was observed. No significant association was observed. Negative Steen, N. E.,2010
rs1051168 WDR73 NMB 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000127, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000127, FDR=0.203, FDR=0.033 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs1691053 SRD5A1 1(0/0/1) 1
Single marker association:ALLELIC Model, chi square=4.7, df...... Single marker association:ALLELIC Model, chi square=4.7, df=1, P-value = 0.03;TREND Model, chi square=4.52, df=1, P-value = 0.034 More... Significant association was found. Significant association was found. Positive Steen, N. E.,2010
rs12601930 PPP1R1B STARD3 1(1/0/0) 1
Genotypic P-value = 0.190, Armitage's P-value = 0.271. alle...... Genotypic P-value = 0.190, Armitage's P-value = 0.271. allelic P-value = 0.287 in SZ. More... Single-marker in a sample set showed that PPP1R1B polymorph...... Single-marker in a sample set showed that PPP1R1B polymorphisms were not significantly associated with schizophrenia. More... Negative Yoshimi, A., 2008
rs13211507 PGBD1 1(0/0/1) 1
Association results in schizophrenia follow-up samples(10,6...... Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.22 (1.14, 1.31),P-value = 5.2 x 10-9 More... The SNP showed a significant association with SZ. The SNP showed a significant association with SZ. Positive Steinberg, S.,2012
rs885988 TBX1 1(0/0/1) 1
X2= 0.125, P-value = 0.723 for schizophrenia w...... X2= 0.125, P-value = 0.723 for schizophrenia when compared with controls. More... None of the nine individual SNPs showed a positive associat...... None of the nine individual SNPs showed a positive association in the 'all affecteds' category. More... Negative Funke, B. H., 2007
rs1358278 FOXP2 1(0/0/1) 1
Association analysis:OR(95%CI) = 1.005(0.89–1.13),allelic...... Association analysis:OR(95%CI) = 1.005(0.89–1.13),allelic P-value = 0.938,genotypic P-value = 0.674 More... No significant association was found. No significant association was found. Negative Li, T.,2013
rs12191311 MDGA1 1(0/0/1) 1
Single SNP analyses:allele, P-value = 0.4713, OR[95%CI]=0.9...... Single SNP analyses:allele, P-value = 0.4713, OR[95%CI]=0.9517[0.8318, 1.0889], genotype, P-value = 0.624 for SZ More... No significant association was observed. No significant association was observed. Negative Li, J.,2011(a)
rs1952157 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.4474 Alelle association:P-value = 0.4474 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs217520 NR2E1 1(1/0/0) 1
X2=2.26, OR (95% CI)=0.85 (0.69-1.06), P-value =...... X2=2.26, OR (95% CI)=0.85 (0.69-1.06), P-value = 0.133 for SZ. More... No association was detected with schizophrenia. No association was detected with schizophrenia. Negative Kumar, R. A., 2008
rs391695 DAOA 1(1/0/0) 1
allelic P-value = 0.27 in Schizophrenia allelic P-value = 0.27 in Schizophrenia We found no evidence for allelic or genotypic association w...... We found no evidence for allelic or genotypic association with any of the polymorphisms studied for schizophrenia. More... Negative Williams, N. M., 2006
rs6927023 GPX6 1(1/0/0) 1
First-set screening: P-valuecorrected=0.16, P-va...... First-set screening: P-valuecorrected=0.16, P-value=0.00384, OR=1.46, 95%CI=1.13-1.88 More... Significant association was observed. Significant association was observed. Positive Saito T., 2014
rs17138230 TENM4 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.03822 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.03822 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs4789846 CSNK1D 1(0/0/1) 1
Chi square test:MAF = 0.25,P-value = 0.65,OR = 0.97 Chi square test:MAF = 0.25,P-value = 0.65,OR = 0.97 No significant association was observed. No significant association was observed. Negative Matsunaga, S.,2012
rs6502097 SECTM1 CSNK1D 1(1/0/0) 1
Chi square test:MAF = 0.16,P-value = 0.15,OR = 1.13 Chi square test:MAF = 0.16,P-value = 0.15,OR = 1.13 No significant association was observed. No significant association was observed. Negative Matsunaga, S.,2012
rs4785714 ZNF276 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00134, FDR=0....... Conditional FDR; SCZ loci given BD: P-value=0.00134, FDR=0.527, FDR=0.034 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs1064512 SLC1A4 RNU6-548P 1(0/0/1) 1
no P-value no P-value Allele and haplotype frequencies did not differ between cas...... Allele and haplotype frequencies did not differ between cases and controls. More... Negative Skowronek, M. H., 2006
rs9379780 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.00000378, FDR...... Conditional FDR; SCZ loci given BD: P-value=0.00000378, FDR=0.065, FDR=0.024 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.26. More... Positive Andreassen OA, 2013
rs9462875 CUL9 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.000161, FDR=0...... Conditional FDR; SCZ loci given BD: P-value=0.000161, FDR=0.229, FDR=0.036 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs12223186 FEZ1 1(0/0/1) 1
Allelic P-value = 0.203, genotypic P-value = 0.363 in Cau...... Allelic P-value = 0.203, genotypic P-value = 0.363 in Caucasians. Allelic P-value = 0.877, genotypic P-value = 0.835 in African Americans. More... No association to schizophrenia was found for any of the ni...... No association to schizophrenia was found for any of the nine markers typed in these populations at the allelic or the genotypic level. More... Negative Hodgkinson, C. A., 2007
rs9819616 RBMS3 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs1440199 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.1904 Alelle association:P-value = 0.1904 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2097063 COMT 1(0/0/1) 1
Allelic association:for SCZ, P-value = 0.011, trend P-value...... Allelic association:for SCZ, P-value = 0.011, trend P-value = 0.014, OR (95%CI)=1.39(1.08, 1.79);for SCZ+SA, P-value = 0.015, trend P-value = 0.019, OR (95%CI)=1.33(1.06, 1.67) More... Significant association was observed in SZ. Significant association was observed in SZ. Positive Funke, B.,2005
rs6982836 RPL31P40 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.04168 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.04168 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs10113797 NRG1 1(0/0/1) 1
Individual P-value = 0.1911 for SCZ , Individual P-value = ...... Individual P-value = 0.1911 for SCZ , Individual P-value = 0.1981 for SCZ and BP More... Negative Thomson, P. A., 2007
rs271738 IRF2BP2 1(0/0/1) 1
logistic regression:P-value > E-05 logistic regression:P-value > E-05 No significant association was observed in SZ. No significant association was observed in SZ. Negative Bergen, S. E.,2012
rs11160562 EML1 1(1/0/0) 1
Conditional FDR; BD loci given SCZ: FDR=0.03496 for BD and ...... Conditional FDR; BD loci given SCZ: FDR=0.03496 for BD and SCZ More... This SNP is with conditional FDR<0.05 in schizophrenia give...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More... Positive Andreassen OA, 2013
rs8017303 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.5964 Alelle association:P-value = 0.5964 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2859387 PER3 1(1/0/0) 1
TDT P-value = 0.02, X2=5.36, df=1, Trends test=0...... TDT P-value = 0.02, X2=5.36, df=1, Trends test=0.168 for Pittsburgh SZ/SZA More... When we analyzed transmission bias in the SZ/SZA samples, w...... When we analyzed transmission bias in the SZ/SZA samples, we observed significant transmission distortion at this loci. More... Positive Mansour, H. A., 2006
rs10893385 FEZ1 1(0/0/1) 1
Allelic P-value = 0.625, genotypic P-value = 0.551 in Cau...... Allelic P-value = 0.625, genotypic P-value = 0.551 in Caucasians. Allelic P-value = 0.450, genotypic P-value = 0.262 in African Americans. More... No association to schizophrenia was found for any of the ni...... No association to schizophrenia was found for any of the nine markers typed in these populations at the allelic or the genotypic level. More... Negative Hodgkinson, C. A., 2007
rs2269577 XBP1 1(1/0/0) 1
GG vs. CC: Illness types (Schizophrenia): OR=1.15, 95%CI=0....... GG vs. CC: Illness types (Schizophrenia): OR=1.15, 95%CI=0.93-1.41. Asian Illness (Schizophrenia): OR=1.24, 95%CI=0.66-2.33. European Illness (Schizophrenia): OR=1.07, 95%CI=0.79-1.45. CG vs. CC: Illness types (Schizophrenia): OR=1.14, 95%CI=0.93-1.40. Asian Illness (Schizophrenia): OR=1.13, 95%CI=0.63-2.04. European Illness (Schizophrenia): OR=1.19, 95%CI=0.88-1.61. GG+CG vs. CC: Illness types (Schizophrenia): OR=1.15, 95%CI=0.94-1.40. Asian Illness (Schizophrenia): OR=1.18, 95%CI=0.66-2.14. European Illness (Schizophrenia): OR=1.13, 95%CI=0.85-1.52. GG vs. CG+CC: Illness types (Schizophrenia): OR=1.01, 95%CI=0.89-1.14. Asian Illness (Schizophrenia): OR=1.11, 95%CI=0.94-1.32. European Illness (Schizophrenia): OR=0.91, 95%CI=0.77-1.08. More... No significant association was found. No significant association was found. Negative Cheng, D., 2014
rs1882019 HSP90B1 1(0/0/1) 1
chi-square genotypic P-value = 0.7379, allelic P-value = 0....... chi-square genotypic P-value = 0.7379, allelic P-value = 0.8173 for SZ cases in total samples More... No significant association was observed in single SNPs. How...... No significant association was observed in single SNPs. However, the result should be treated with caution, because there was a significant difference of gender between patients with schizophrenia and controls. More... Negative Kakiuchi, C., 2007 (a)
rs6079501 MACROD2 MACROD2-IT1 SEL1L2 1(0/0/1) 1
Omnibus GWAS Test:P-value > 5E-05 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. No significant association was observed. Negative Huang, J.,2010
rs6913660 HIST1H2BJ 1(0/0/1) 1
Association results in schizophrenia follow-up samples(10,6...... Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.11 (1.06, 1.17),P-value = 2.3 x 10-5 More... No significant association was observed. No significant association was observed. Negative Steinberg, S.,2012
rs3766293 FABP3 ZCCHC17 1(0/0/1) 1
allele test P-value = 0.058, genotype test P-value = 0.139 allele test P-value = 0.058, genotype test P-value = 0.139 None of the 8 SNPs showed association with schizophrenia. None of the 8 SNPs showed association with schizophrenia. Negative Iwayama, Y., 2010
rs243301 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.833 Alelle association:P-value = 0.833 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs7305141 PAWR 1(0/0/1) 1
Hardy-Weinberg equilibrium P value=0.0556, genotypic P valu...... Hardy-Weinberg equilibrium P value=0.0556, genotypic P value=0.986, allelic P value=0.237 for schizophrenia compared with controls. More... No association was detected with schizophrenia or MDD in al...... No association was detected with schizophrenia or MDD in allele/genotype-wise analyses. More... Negative Kishi, T., 2008 (a)
rs7106715 1(1/0/0) 1
Conditional FDR; SCZ loci given BD: P-value=0.0000652, FDR=...... Conditional FDR; SCZ loci given BD: P-value=0.0000652, FDR=0.143, FDR=0.039 for SCZ and BD More... To estimate the number of independent loci, we 'pruned' the...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive Andreassen OA, 2013
rs2323019 FZD3 RNA5SP259 1(0/0/1) 1
Allelic association:P-value = 0.57 for SZ Allelic association:P-value = 0.57 for SZ No significant association was observed in SZ. No significant association was observed in SZ. Negative Hashimoto, R.,2005(b)
rs1952075 NPAS3 1(0/0/1) 1
Alelle association:P-value = 0.578 Alelle association:P-value = 0.578 No significant association was observed No significant association was observed Negative Pickard, B. S.,2009
rs2304674 PER2 1(0/0/1) 1
Single SNP-based analyses:Trends test P-value = 0.033 in SZ Single SNP-based analyses:Trends test P-value = 0.033 in SZ Significant association was observed Significant association was observed Positive Mansour, H. A.,2009
rs1481747 NRG1 1(0/0/1) 1
Individual P-value = 0.7276 for SCZ , Individual P-value = ...... Individual P-value = 0.7276 for SCZ , Individual P-value = 0.9216 for SCZ and BP More... Negative Thomson, P. A., 2007
rs7015249 NRG1 1(0/0/1) 1
Individual P-value = 0.1964 for SCZ , Individual P-value = ...... Individual P-value = 0.1964 for SCZ , Individual P-value = 0.3427 for SCZ and BP More... Negative Thomson, P. A., 2007

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016