SNP Report

Basic Info

Name	rs7532813 dbSNP Ensembl
Location	chr1:31355410 - 31355410(1)
Variant Alleles	G/C
Ancestral Allele	C
Minor Allele	G
Minor Allele Frequence	0.291534
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000344147, ENST00000373714, ENST00000546109, ENST00000615916, ENST00000616393, ENST00000616859, ENST00000618216, ENST00000627541)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Iwayama, Y., 2010	G/C		allele test P-value = 0.5189, genotype test P-value = 0.7491 allele test P-value = 0.5189, genotype test P-value = 0.7491	None of the 8 SNPs showed association with bipolar disorder None of the 8 SNPs showed association with bipolar disorder	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ZCCHC17	zinc finger, CCHC domain containing 17	1p35.2	Mapped by Literature SNP
FABP3	fatty acid binding protein 3, muscle and heart	1p33-p32	2(1/1/0)

SNPs in LD with rs7532813 (count: 23) View in gBrowse (chr1:31233789..31413316 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 23)

rs_ID	Functional Annotation	r²[population]
rs6425742	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.95[CHB]; 1.0[JPT]
rs12401792	intron_variant; upstream_gene_variant	0.947[CHB]; 1.0[JPT]
rs10753248	intron_variant; non_coding_transcript_variant	0.95[CHB]; 1.0[JPT]
rs7533667	intron_variant; non_coding_transcript_variant	0.947[CHB]; 1.0[JPT]
rs12564155	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.947[CHB]; 1.0[JPT]
rs12566574	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.8[CHB]; 1.0[JPT]
rs6425741	downstream_gene_variant; intron_variant; non_coding_transcript_variant	0.948[CHB]; 1.0[JPT]
rs2377728	intron_variant	0.949[JPT]
rs756352	intron_variant; non_coding_transcript_variant	0.947[CHB]; 1.0[JPT]
rs10914350	intron_variant; non_coding_transcript_variant	0.947[CHB]; 1.0[JPT]
rs3753373	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.84[CHB]; 0.949[JPT]
rs12026718	intron_variant	0.9[JPT]
rs12042883	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.8[CHB]
rs2889753		0.812[CHB]
rs7539952	intron_variant; non_coding_transcript_variant	0.8[CHB]; 1.0[JPT]
rs1532858	downstream_gene_variant; intron_variant; upstream_gene_variant	0.8[CHB]; 1.0[JPT]
rs4949203	intron_variant; non_coding_transcript_variant	0.947[CHB]; 1.0[JPT]
rs924930	downstream_gene_variant	0.84[CHB]; 1.0[JPT]
rs7549339		1.0[JPT]
rs6425730	intron_variant; non_coding_transcript_variant; upstream_gene_variant	0.84[CHB]; 1.0[JPT]
rs905929		0.807[CHB]
rs10914372		0.8[CHB]
rs4949388	intron_variant; non_coding_transcript_variant	0.95[CHB]; 1.0[JPT]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Iwayama, Y., 2010	allele test P-value = 0.6697, genotype test P-value = 0.5818	None of the 8 SNPs showed association with schizophrenia.	Negative

Overlap with MDD from cross-disorder studies (count: 0)