SNP Report

Basic Info

Name	rs2799573 dbSNP Ensembl
Location	chr10:18312999 - 18312999(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.126398
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000282343, ENST00000324631, ENST00000352115, ENST00000377319, ENST00000377328, ENST00000377331, ENST00000396576, ENST00000615785, ENST00000617363)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Cross-Disorder Group of the Psychiatric Genomics Consortium,2013	T/C		Association analysis:P-value = 0.0000000429,OR(95%CI) = 1.08...... Association analysis:P-value = 0.0000000429,OR(95%CI) = 1.08(1.05-1.12) when five disorders were combined More...	Significant association was observed in cross-disorder analy...... Significant association was observed in cross-disorder analysis. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CACNB2	calcium channel, voltage-dependent, beta 2 subunit	10p12	3(2/1/0)

SNPs in LD with rs2799573 (count: 0) View in gBrowse (chr10:18312999..18312999 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Cross-Disorder Group of the Psychiatric Genomics Consortium,2013	Association analysis:P-value = 0.0000000429,OR(95%CI) = 1.08(1.05-1.12) when five disorders were combined	Significant association was observed in cross-disorder analysis.	Positive

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Cross-Disorder Group of the Psychiatric Genomics Consortium,2013	Association analysis:P-value = 0.0000000429,OR(95%CI) = 1.08(1.05-1.12) when five disorders were combined	Significant association was observed in cross-disorder analysis.	Positive