SNP Report

Basic Info

Name	rs4777760 dbSNP Ensembl
Location	chr15:93059088 - 93059088(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.399561
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000329082, ENST00000425933, ENST00000542321, ENST00000543599, ENST00000554387, ENST00000555584, ENST00000555598, ENST00000556658, ENST00000557301, ENST00000557420); NMD_transcript_variant(ENST00000554387); non_coding_transcript_variant(ENST00000555584)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
McAuley, E. Z., 2012	A/G		P-value = 0.042, Empirical P-value = 0.045, OR (95% CI)=0.74...... P-value = 0.042, Empirical P-value = 0.045, OR (95% CI)=0.74 (0.58-1.03) in the Australian bipolar disorder cohort More...	Nominally significant association (P < 0.05) was found with ...... Nominally significant association (P < 0.05) was found with 18 SNPs. Association with 14 of these SNPs held true when empirical P values were obtained through 10, 000 replicate permutations. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
RGMA	repulsive guidance molecule family member a	15q26.1	1(1/0/0)

SNPs in LD with rs4777760 (count: 0) View in gBrowse (chr15:93059088..93059088 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
McAuley, E. Z., 2012	P-value > 0.075	Single SNP analysis did not yield significant evidence for association.	Negative

Overlap with MDD from cross-disorder studies (count: 0)