Gene Report

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Basic Info

Approved Symbol	IFI44L
Previous Symbol	C1orf29
Symbol Alias	GS3686
Approved Name	interferon-induced protein 44-like
Previous Name	chromosome 1 open reading frame 29
Location	1p22.3
Position	chr1:78619922-78646145, 1
External Links	HGNC: 17817 Entrez Gene: 10964 Ensembl: ENSG00000137959 UCSC: uc010oro.2
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	YES
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Ruderfer, D. M., 2013	SNP: rs4650608	The SNP within or near this gene did not achieve genome-wide significance.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 3)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0051607	defense response to virus	biological process	IEA	6
GO:0006955	immune response	biological process	IEA	19
GO:0005737	cytoplasm	cellular component	IEA	322

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs4650608	chr1:78772330 - 78772330(1)		3(2/1/0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
1p32.1-q31.1	chr1:58500000-190800000	1 (0/1/0)
1p31.1-p22.1	chr1:69300000-94300000	1 (0/1/0)
Chr 1	chr1:0-248956422	2 (0/2/0)
1p31.1	chr1:69300000-84400000	0

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Reference	Description	Result Category
24280982	The SNP within or near this gene did not achieve genome-wide significance.	Negative

Gene relationship with MDD

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Region: chr1:78619922..78646145 View in gBrowse