SNP Report

Basic Info

Name	rs6459806 dbSNP Ensembl
Location	chrCHR_HSCHR7_2_CTG7:157717791 - 157717791(1)
Variant Alleles	G/C
Ancestral Allele	G
Minor Allele	C
Minor Allele Frequence	0.428914
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000389413, ENST00000389416, ENST00000389418, ENST00000409483)
No. of Studies	1 (Positive: 0; Negative: 0; Trend: 1)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Curtis, D.,2011			chi suqare test: SZ v.BP, P-value = E-5.1; BP v.C, P-value =...... chi suqare test: SZ v.BP, P-value = E-5.1; BP v.C, P-value = 6.3E-03 More...	Suggestive association was found. Suggestive association was found.	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2	7q36	1(0/0/1)

SNPs in LD with rs6459806 (count: 2) View in gBrowse (chrCHR_HSCHR7_2_CTG7:157717602..157719598 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs10233396		intron_variant	1.0[CEU]; 0.853[TSI]
rs6459805		intron_variant	1.0[CEU]; 1.0[TSI]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Curtis, D.,2011	chi suqare test:SZ v.BP, P-value = E-5.1;SZ v.C, P-value = E-1	Suggestive association was found.	Trend

Overlap with MDD from cross-disorder studies (count: 0)