Gene Report

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Basic Info

Approved Symbol	POMGNT2
Previous Symbol	C3orf39, GTDC2
Symbol Alias	FLJ14566, AGO61
Approved Name	protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
Previous Name	chromosome 3 open reading frame 39, "glycosyltransferase-like domain containing 2"
Location	3p22.1
Position	chr3:43079232-43106076, -1
External Links	HGNC: 25902 Entrez Gene: 84892 Ensembl: ENSG00000144647
No. of Studies	1 (Positive: 0; Negative: 0; trend: 1)
Overlap with SZ?	YES
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Curtis, D.,2011	SNP: rs17075286	There is a trend of this gene for significant association.	Trend	Comment on Study

Gene functional annotation

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016021	integral component of membrane	cellular component	IEA	219

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0008375	acetylglucosaminyltransferase activity	molecular function	IDA[23929950]	2
GO:0097363	protein O-GlcNAc transferase activity	molecular function	IDA[23929950]	1
GO:0035269	protein O-linked mannosylation	biological process	ISS	2
GO:0005783	endoplasmic reticulum	cellular component	IDA[23929950]	49
GO:0005789	endoplasmic reticulum membrane	cellular component	IEA	52
GO:0001764	neuron migration	biological process	ISS	18
GO:0006493	protein O-linked glycosylation	biological process	IDA[23929950]	6
GO:0005515	protein binding	molecular function	IPI[25416956]	563

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs17075286	chr3:43189231 - 43189231(1)		1(0/0/1)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 3	chr3:0-198295559	2 (0/2/0)
3p22.1	chr3:39300000-43600000	1 (0/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Reference	Description	Result Category
21057379	There is a trend of this gene for significant association.	Trend

Gene relationship with MDD

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Region: chr3:43079232..43106076 View in gBrowse