SNP Report

Basic Info

Name	rs6932590 dbSNP Ensembl
Location	chr6:27281152 - 27281152(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.209065
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000429945)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Steinberg, S.,2012		T	Association results in bipolar disorder follow-up samples(7,...... Association results in bipolar disorder follow-up samples(7,333 cases; 43,779 controls):OR(95% CI) = 1.02 (0.98, 1.08),P-value = 0.33 More...	No significant association was observed. No significant association was observed.	Negative
Williams, H. J.,2011			Armitage trend test: P-value = 0.04, OR=1.09, 95%CI=(0.99-1....... Armitage trend test: P-value = 0.04, OR=1.09, 95%CI=(0.99-1.18) More...	Significant association was found. Significant association was found.	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
POM121L2	POM121 transmembrane nucleoporin-like 2	6p21.3	Mapped by Literature SNP

SNPs in LD with rs6932590 (count: 0) View in gBrowse (chr6:27281152..27281152 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Steinberg, S.,2012	Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.10 (1.05, 1.14),P-value = 2.5 x 10-5	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 0)