SNP Report

Basic Info

Name	rs4789846 dbSNP Ensembl
Location	chr17:82267669 - 82267669(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.111222
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000314028, ENST00000392334, ENST00000398519, ENST00000403276, ENST00000578194, ENST00000579308, ENST00000579316, ENST00000580446, ENST00000581241, ENST00000581655, ENST00000581660, ENST00000582844, ENST00000584472, ENST00000585026); NMD_transcript_variant(ENST00000403276, ENST00000581660, ENST00000585026); non_coding_transcript_variant(ENST00000578194, ENST00000579308, ENST00000579316, ENST00000581241, ENST00000581655, ENST00000582844, ENST00000584472); upstream_gene_variant(ENST00000580061)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Matsunaga, S.,2012	T/C		Chi square test:MAF = 0.25,P-value = 0.57,OR = 0.96 Chi square test:MAF = 0.25,P-value = 0.57,OR = 0.96	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CSNK1D	casein kinase 1, delta	17q25	4(2/2/0)

SNPs in LD with rs4789846 (count: 0) View in gBrowse (chr17:82267669..82267669 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Matsunaga, S.,2012	Chi square test:MAF = 0.25,P-value = 0.65,OR = 0.97	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Matsunaga, S.,2012	Chi square test:MAF = 0.29,P-value = 0.068,OR = 1.17	No significant association was observed.	Negative