SNP Report

Basic Info

Name	rs12807809 dbSNP Ensembl
Location	chr11:124736389 - 124736389(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	C
Minor Allele Frequence	0.203874
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000284292, ENST00000412681)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Williams, H. J.,2011			Armitage trend test: P-value = 0.02, OR=1.14, 95%CI=(1.01-1....... Armitage trend test: P-value = 0.02, OR=1.14, 95%CI=(1.01-1.27) More...	Significant association was found. Significant association was found.	Positive
Steinberg, S.,2012		T	Association results in bipolar disorder follow-up samples(7,...... Association results in bipolar disorder follow-up samples(7,333 cases; 43,779 controls):OR(95% CI) = 1.09 (1.03, 1.16),P-value = 0.0023 More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NRGN	neurogranin (protein kinase C substrate, RC3)	11q24	2(1/1/0)

SNPs in LD with rs12807809 (count: 0) View in gBrowse (chr11:124736389..124736389 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Steinberg, S.,2012	Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.09 (1.04, 1.15),P-value = 0.00034	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 0)