BDgene

SNP Report

Basic Info
Name rs12807809 dbSNP Ensembl
Location chr11:124736389 - 124736389(1)
Variant Alleles T/C
Ancestral Allele C
Minor Allele C
Minor Allele Frequence 0.203874
Functional Annotation upstream_gene_variant.
Consequence to Transcript upstream_gene_variant(ENST00000284292, ENST00000412681)
No. of Studies 2 (Positive: 1; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Williams, H. J.,2011 Armitage trend test: P-value = 0.02, OR=1.14, 95%CI=(1.01-1....... Armitage trend test: P-value = 0.02, OR=1.14, 95%CI=(1.01-1.27) More... Significant association was found. Significant association was found. Positive
Steinberg, S.,2012 T Association results in bipolar disorder follow-up samples(7,...... Association results in bipolar disorder follow-up samples(7,333 cases; 43,779 controls):OR(95% CI) = 1.09 (1.03, 1.16),P-value = 0.0023 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
NRGN neurogranin (protein kinase C substrate, RC3) 11q24 2(1/1/0)

SNPs in LD with rs12807809 (count: 0) View in gBrowse (chr11:124736389..124736389 )

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Steinberg, S.,2012 Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.09 (1.04, 1.15),P-value = 0.00034 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 0)