SNP Report

Basic Info

Name	rs3766293 dbSNP Ensembl
Location	chr1:31364349 - 31364349(1)
Variant Alleles	G/T
Ancestral Allele	G
Minor Allele	T
Minor Allele Frequence	0.034345
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000344147, ENST00000373714, ENST00000546109, ENST00000615916, ENST00000616393, ENST00000616859, ENST00000618216, ENST00000627541); downstream_gene_variant(ENST00000373713, ENST00000482018, ENST00000497275, ENST00000498148)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Iwayama, Y., 2010	A/C		allele test P-value = 0.1916, genotype test P-value = 0.2176 allele test P-value = 0.1916, genotype test P-value = 0.2176	None of the 8 SNPs showed association with bipolar disorder None of the 8 SNPs showed association with bipolar disorder	Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
ZCCHC17	zinc finger, CCHC domain containing 17	1p35.2	Mapped by Literature SNP
FABP3	fatty acid binding protein 3, muscle and heart	1p33-p32	2(1/1/0)

SNPs in LD with rs3766293 (count: 7) View in gBrowse (chr1:31245216..31424411 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs3737754	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs9970421	intron_variant; non_coding_transcript_variant	0.864[CHB]; 1.0[JPT]
rs3737753	intron_variant; non_coding_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs2185420		0.846[CHB]; 1.0[JPT]
rs3766288	intron_variant; non_coding_transcript_variant	0.864[CHB]; 1.0[CHD]; 1.0[JPT]
rs2292164	3_prime_UTR_variant; downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.822[CHB]; 1.0[CHD]; 1.0[JPT]
rs1317252	intron_variant; non_coding_transcript_variant	1.0[CHB]; 0.953[CHD]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Iwayama, Y., 2010	allele test P-value = 0.058, genotype test P-value = 0.139	None of the 8 SNPs showed association with schizophrenia.	Negative

Overlap with MDD from cross-disorder studies (count: 0)