Gene Report

Basic Info
Approved Symbol MMP16
Previous Symbol C8orf57
Symbol Alias MT3-MMP, DKFZp761D112
Approved Name matrix metallopeptidase 16 (membrane-inserted)
Previous Name matrix metalloproteinase 16 (membrane-inserted), "chromosome 8 open reading frame 57"
Location 8q21
Position chr8:88032009-88328025, -1
External Links HGNC: 7162
Entrez Gene: 4325
Ensembl: ENSG00000156103
UCSC: uc003yeb.4
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Saito T., 2014 SNP: rs7004633 The associated SNP in this gene showed no significant association with BD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 18)

GO terms by PBA (count: 5)

GO terms by database search (count: 13)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

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Region: chr8:88032009..88328025 View in gBrowse
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