BDgene

SNP Report

Basic Info
Name rs55909231 dbSNP Ensembl
Location chr19:51001974 - 51001974(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.0245607
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000544410, ENST00000594211); intron_variant(ENST00000250366, ENST00000594512, ENST00000595238, ENST00000599166, ENST00000600767); NMD_transcript_variant(ENST00000250366, ENST00000599166); non_coding_transcript_variant(ENST00000594512); upstream_gene_variant(ENST00000291726, ENST00000320838, ENST00000347619, ENST00000391806, ENST00000593490, ENST00000594669, ENST00000594914, ENST00000598195, ENST00000599710)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? YES

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Izumi, A., 2008 A>G Genotype frequency (df=2) X2=0.4, P value=0.81 . ...... Genotype frequency (df=2) X2=0.4, P value=0.81 . Allele frequency (df=1) X2=0.36, P value=0.54 in Patients with BD vs controls. More... Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
KLK9 kallikrein-related peptidase 9 19q13.33 Mapped by Literature SNP
KLK8 kallikrein-related peptidase 8 19q13 1(1/0/0)

SNPs in LD with rs55909231 (count: 0) View in gBrowse (chr19:51001974..51001974 )

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Izumi, A., 2008 Genotype frequency (df=2) X2=0.21, P value=0.90. Allele frequency (df=1) X2=0.11, P value=0.74 in Patients with SZ vs controls. There was no significant difference in genotype or allele distribution for any SNP between patients and controls for schizophrenia or major depression. Negative

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Izumi, A., 2008 Genotype frequency (df=2) X2=4.94, P value=0.08 . Allele frequency (df=1) X2=2.48, P value=0.12 in Patients with MD vs controls. There was no significant difference in genotype or allele distribution for any SNP between patients and controls for schizophrenia or major depression. Negative