SNP Report

Basic Info

Name	rs55909231 dbSNP Ensembl
Location	chr19:51001974 - 51001974(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.0245607
Functional Annotation	downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000544410, ENST00000594211); intron_variant(ENST00000250366, ENST00000594512, ENST00000595238, ENST00000599166, ENST00000600767); NMD_transcript_variant(ENST00000250366, ENST00000599166); non_coding_transcript_variant(ENST00000594512); upstream_gene_variant(ENST00000291726, ENST00000320838, ENST00000347619, ENST00000391806, ENST00000593490, ENST00000594669, ENST00000594914, ENST00000598195, ENST00000599710)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Izumi, A., 2008	A>G		Genotype frequency (df=2) X²=0.4, P value=0.81 . ...... Genotype frequency (df=2) X²=0.4, P value=0.81 . Allele frequency (df=1) X²=0.36, P value=0.54 in Patients with BD vs controls. More...		Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
KLK9	kallikrein-related peptidase 9	19q13.33	Mapped by Literature SNP
KLK8	kallikrein-related peptidase 8	19q13	1(1/0/0)

SNPs in LD with rs55909231 (count: 0) View in gBrowse (chr19:51001974..51001974 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Izumi, A., 2008	Genotype frequency (df=2) X²=0.21, P value=0.90. Allele frequency (df=1) X²=0.11, P value=0.74 in Patients with SZ vs controls.	There was no significant difference in genotype or allele distribution for any SNP between patients and controls for schizophrenia or major depression.	Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Izumi, A., 2008	Genotype frequency (df=2) X²=4.94, P value=0.08 . Allele frequency (df=1) X²=2.48, P value=0.12 in Patients with MD vs controls.	There was no significant difference in genotype or allele distribution for any SNP between patients and controls for schizophrenia or major depression.	Negative