SNP Report

Basic Info

Name	rs2301558 dbSNP Ensembl
Location	chr22:19764306 - 19764306(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.341254
Functional Annotation	downstream_gene_variant; synonymous_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000475303); synonymous_variant(ENST00000329705, ENST00000332710, ENST00000359500, ENST00000621939, LRG_226t1); upstream_gene_variant(ENST00000484336)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Funke, B. H., 2007	C/T	C	X²= 1.676, P-value = 0.195 for affective disorde...... X²= 1.676, P-value = 0.195 for affective disorder (BP + MDD) when compared with controls More...	None of the nine individual SNPs showed a positive associati...... None of the nine individual SNPs showed a positive association in the 'all affecteds' category. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TBX1	T-box 1	22q11.21	Mapped by Literature SNP

SNPs in LD with rs2301558 (count: 0) View in gBrowse (chr22:19764306..19764306 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Funke, B. H., 2007	X²= 0.046, P-value = 0.830 for schizophrenia when compared with controls.	None of the nine individual SNPs showed a positive association in the 'all affecteds' category.	Negative

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Funke, B. H., 2007	X²= 1.676, P-value = 0.195 for affective disorder (BP + MDD) when compared with controls	None of the nine individual SNPs showed a positive association in the 'all affecteds' category.	Negative