BDgene

SNP Report

Basic Info
Name rs9960767 dbSNP Ensembl
Location chr18:55487771 - 55487771(1)
Variant Alleles A/C
Ancestral Allele A
Minor Allele C
Minor Allele Frequence 0.138379
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant.
Consequence to Transcript downstream_gene_variant(ENST00000587660); intron_variant(ENST00000354452, ENST00000356073, ENST00000398339, ENST00000537578, ENST00000540999, ENST00000543082, ENST00000562543, ENST00000562847, ENST00000563824, ENST00000563888, ENST00000564343, ENST00000564403, ENST00000564999, ENST00000565018, ENST00000565124, ENST00000565580, ENST00000565908, ENST00000566279, ENST00000566286, ENST00000566514, ENST00000567880, ENST00000568147, ENST00000568169, ENST00000568673, ENST00000568740, ENST00000569357, ENST00000616053, ENST00000625716, ENST00000626425, ENST00000626595, ENST00000627136, ENST00000627320, ENST00000627685, ENST00000627784, ENST00000629387, ENST00000630224, ENST00000630319, ENST00000635822, ENST00000636400, ENST00000636751, ENST00000637115, ENST00000637239, ENST00000638154); NMD_transcript_variant(ENST00000569357, ENST00000627320, ENST00000630224, ENST00000636751, ENST00000637115); non_coding_transcript_variant(ENST00000565580, ENST00000625716, ENST00000627136, ENST00000637239); upstream_gene_variant(ENST00000586467)
No. of Studies 2 (Positive: 0; Negative: 2; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Williams, H. J.,2011 Armitage trend test: P-value = 0.92, OR=0.99, 95%CI=(0.80-1....... Armitage trend test: P-value = 0.92, OR=0.99, 95%CI=(0.80-1.18) More... No significant association was observed in BD. No significant association was observed in BD. Negative
Steinberg, S.,2012 C Association results in bipolar disorder follow-up samples(7,...... Association results in bipolar disorder follow-up samples(7,333 cases; 43,779 controls):OR(95% CI) = 1.03 (0.94, 1.13),P-value = 0.57 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
TCF4 transcription factor 4 18q21.1 6(1/5/0)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 10q25.3 1(1/0/0)

SNPs in LD with rs9960767 (count: 0) View in gBrowse (chr18:55487771..55487771 )

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Steinberg, S.,2012 Association results in schizophrenia follow-up samples(10,671 cases; 23,900 controls):OR(95% CI) = 1.14 (1.06, 1.23),P-value = 0.00057 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 0)