BDgene

SNP Report

Basic Info
Name rs4757142 dbSNP Ensembl
Location chr11:13304148 - 13304148(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.409744
Functional Annotation intron_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000389707, ENST00000401424, ENST00000403290, ENST00000403510, ENST00000480685, ENST00000482049, ENST00000527998, ENST00000529050, ENST00000529388, ENST00000529825, ENST00000530357, ENST00000533520, ENST00000534544); non_coding_transcript_variant(ENST00000480685)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Mansour, H. A., 2006 G/A TDT P-value = 0.597 in the samples combined, Pittsburgh Tren...... TDT P-value = 0.597 in the samples combined, Pittsburgh Trends test=0.0008 for BDI More... For the contrasts of genotype distributions for individuals ...... For the contrasts of genotype distributions for individuals from the Pittsburgh sample diagnosed with BD1 vs. the population in general, significant differences were detected. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ARNTL aryl hydrocarbon receptor nuclear translocator-like 11p15 7(5/2/0)

SNPs in LD with rs4757142 (count: 3) View in gBrowse (chr11:13304148..13314379 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 3)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Mansour, H. A., 2006 not analyzed for Pittsburgh SZ/SZA Negative

Overlap with MDD from cross-disorder studies (count: 0)