BDgene

Gene Report

Basic Info
Approved Symbol NPTX1
Approved Name neuronal pentraxin I
Location 17q25.3
Position chr17:80467148-80477843, -1
External Links HGNC: 7952
Entrez Gene: 4884
Ensembl: ENSG00000171246
UCSC: uc002jyp.1
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Rajkumar, A. P., 2014 SNP: rs11657796 After Bonferroni corrections, NPTX1 was the only gene that showed a study-wise significant association with BD. Positive Comment on Study
Bergen, S. E.,2012 SNP: rs11150863 No significant association was observed in BD. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 13)

GO terms by PBA (count: 3)

GO terms by database search (count: 10)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 2)

Related other genetic factors
Gene related SNPs (count: 2)

Literature-origin SNPs (count: 2)

LD-proxies (count: 0)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)


Gene relationship with MDD

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Region: chr17:80467148..80477843 View in gBrowse
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