Gene Report

Basic Info
Approved Symbol SLC1A4
Symbol Alias SATT, ASCT1
Approved Name solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
Name Alias alanine/serine/cysteine/threonine transporter
Location 2p15-p13
Position chr2:64988477-65023865, 1
External Links HGNC: 10942
Entrez Gene: 6509
Ensembl: ENSG00000115902
UCSC: uc010yqa.2
No. of Studies 1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Skowronek, M. H., 2006 SNP: rs1064512, rs2075209, rs3732062, rs759458
Other variant: SLC1A4-11
Our results do not support an association of the ASCT1 gene with BD or SCZ in the German population. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 38)

GO terms by PBA (count: 6)

GO terms by database search (count: 32)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 6)

Literature-origin SNPs (count: 4)

LD-proxies (count: 2)

Gene related CNVs (count: 0)

Gene related other variants (count: 1)

Gene related regions (count: 7)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 2)

Gene relationship with MDD

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Region: chr2:64988477..65023865 View in gBrowse
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