SNP Report

Basic Info

Name	rs28757218 dbSNP Ensembl
Location	chr14:56805348 - 56805348(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.00439297
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000339475, ENST00000408990, ENST00000554559, ENST00000554788, ENST00000554845, ENST00000555006, ENST00000555804)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Sabunciyan, S., 2007	G/T		chi-square P-value = 0.003, OR=3.5, 95% CI: 1.4-10.4 chi-square P-value = 0.003, OR=3.5, 95% CI: 1.4-10.4	rs28757218 allele was associated with bipolar disorder in th...... rs28757218 allele was associated with bipolar disorder in the samples studied More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
OTX2	orthodenticle homeobox 2	14q22.3	1(1/0/0)

SNPs in LD with rs28757218 (count: 0) View in gBrowse (chr14:56805348..56805348 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Sabunciyan, S., 2007	no P-value given	the rate did not differ significantly from that observed in the control population	Negative

Overlap with MDD from cross-disorder studies (count: 0)