BDgene

SNP Report

Basic Info
Name rs12539410 dbSNP Ensembl
Location chr7:132381325 - 132381325(1)
Variant Alleles G/C
Ancestral Allele G
Minor Allele C
Minor Allele Frequence 0.0976438
Functional Annotation downstream_gene_variant; intron_variant.
Consequence to Transcript downstream_gene_variant(ENST00000423507); intron_variant(ENST00000321063, ENST00000359827)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? YES

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Huang, J.,2010 C/G Omnibus GWAS Test: P-value > 5E-05 Omnibus GWAS Test: P-value > 5E-05 No significant association was observed in BD. No significant association was observed in BD. Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
PLXNA4 plexin A4 7q32.3 Mapped by Literature SNP
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 7q33 1(0/1/0)

SNPs in LD with rs12539410 (count: 0) View in gBrowse (chr7:132381325..132381325 )

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Huang, J.,2010 Omnibus GWAS Test:P-value > 5E-05 No significant association was observed. Negative

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Huang, J.,2010 Omnibus GWAS Test:P-value = 0.00000474, best-fit model is Depressive disorders Suggestive association was found. Trend