SNP Report

Basic Info

Name	rs3802177 dbSNP Ensembl
Location	chr8:117172786 - 117172786(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.25619
Functional Annotation	3_prime_UTR_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000427715, ENST00000456015, ENST00000519688, ENST00000521243)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Kajio, Y., 2014	T/C		P-value=0.042, Pcorrected=1, OR=1.15 for BD in screening sta...... P-value=0.042, Pcorrected=1, OR=1.15 for BD in screening stage More...	SNPs in SLC30A8 (rs3802177, Puncorrected=0.042) showed the o...... SNPs in SLC30A8 (rs3802177, Puncorrected=0.042) showed the opposite direction of effect in the BD associations. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLC30A8	solute carrier family 30 (zinc transporter), member 8	8q24.11	1(1/0/0)

SNPs in LD with rs3802177 (count: 3) View in gBrowse (chr8:117172544..117208031 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs11558471	3_prime_UTR_variant; downstream_gene_variant	0.954[CHB]; 0.976[CHD]; 1.0[JPT]
rs11774700		0.905[CHB]; 1.0[JPT]
rs13266634	missense_variant	1.0[CHB]; 1.0[CHD]; 0.953[JPT]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Kajio, Y., 2014	P-value=0.95, Pcorrected=1, OR=1.00 for SZ in screening stage.	No association was found for SZ.	Negative

Overlap with MDD from cross-disorder studies (count: 0)