SNP Report

Basic Info

Name	rs6461233 dbSNP Ensembl
Location	chr7:2221833 - 2221833(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.367412
Functional Annotation	downstream_gene_variant; intron_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000429779); intron_variant(ENST00000265854, ENST00000399654, ENST00000402746, ENST00000406869, ENST00000429625, ENST00000445959, ENST00000455998); upstream_gene_variant(ENST00000469871)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Andreassen OA, 2013			Conditional FDR; BD loci given SCZ: P-value=0.000519, FDR=0....... Conditional FDR; BD loci given SCZ: P-value=0.000519, FDR=0.57626, FDR=0.02711 for BD and SCZ More...	This SNP is with conditional FDR<0.05 in schizophrenia given...... This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	7p22	5(1/2/2)

SNPs in LD with rs6461233 (count: 0) View in gBrowse (chr7:2221833..2221833 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Andreassen OA, 2013	Conditional FDR; BD loci given SCZ: FDR=0.02711 for BD and SCZ	This SNP is with conditional FDR<0.05 in schizophrenia given association with bipolar disorder after 'pruning'.	Positive

Overlap with MDD from cross-disorder studies (count: 0)