Gene Report

Basic Info
Approved Symbol SP8
Approved Name Sp8 transcription factor
Location 7p21.2
Position chr7:20782283-20786886, -1
External Links HGNC: 19196
Entrez Gene: 221833
Ensembl: ENSG00000164651
UCSC: uc032zgm.1
No. of Studies 3 (Positive: 2; Negative: 0; trend: 1)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 3)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Kondo, K.,2013 SNP: rs2709736, rs2709722 Significant association was observed. Positive Comment on Study
Lee, M. T.,2011 SNP: rs2709722, rs2709736 SNPs close to specificity protein 8 (SP8) are associated with Bipolar I Disorder. Positive Comment on Study
Huang, J.,2010 SNP: rs917815 Suggestive association was found in BD-II. Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 8)

GO terms by PBA (count: 2)

GO terms by database search (count: 6)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 3)

Literature-origin SNPs (count: 3)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 2)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 0)

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Region: chr7:20782283..20786886 View in gBrowse
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