SNP Report

Basic Info

Name	rs40184 dbSNP Ensembl
Location	chrCHR_HSCHR5_3_CTG1:1437345 - 1437345(-1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	T
Minor Allele Frequence	0.413738
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000270349, ENST00000512002); non_coding_transcript_variant(ENST00000512002, ENST00000621716)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Pinsonneault, J. K.,2011			Stanley sample: allele, X² P-value = 0.22, Fisher...... Stanley sample: allele, X² P-value = 0.22, Fisher's exact P-value = 0.27, OR=0.71, 95%CI=0.4-1.2 for BD; X² P-value = 0.61, Fisher's exact P-value = 0.64OR=1.17 for BD More...	No significant association was observed. No significant association was observed.	Negative
Mick, E., 2008		T	TDT X²(df=1)=9.39, P-value = 0.003, OR (95% CI)=1...... TDT X²(df=1)=9.39, P-value = 0.003, OR (95% CI)=1.52(1.12-2.06) More...	Results indicated nominally positive association for four SN...... Results indicated nominally positive association for four SNPs, but only rs41084 survived correction for multiple statistical comparisons. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLC6A3	solute carrier family 6 (neurotransmitter transporter), member 3	5p15.3	11(5/6/0)

SNPs in LD with rs40184 (count: 0) View in gBrowse (chrCHR_HSCHR5_3_CTG1:1437345..1437345 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Pinsonneault, J. K.,2011	Stanley sample:allele, X² P-value = 0.61, Fisher's exact P-value = 0.64OR=1.17 for SZ	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 0)