SNP Report

Basic Info

Name	rs271738 dbSNP Ensembl
Location	chr1:234527144 - 234527144(1)
Variant Alleles	G/A
Ancestral Allele	G
Minor Allele	G
Minor Allele Frequence	0.29393
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000421207, ENST00000435574)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Bergen, S. E.,2012		A	logistic regression: OR=1.32, P-value = 4.81E-06 logistic regression: OR=1.32, P-value = 4.81E-06	No significant association was observed in BD. No significant association was observed in BD.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
IRF2BP2	interferon regulatory factor 2 binding protein 2	1q42.3	1(0/1/0)

SNPs in LD with rs271738 (count: 6) View in gBrowse (chr1:234526643..234535521 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs271742	intron_variant; non_coding_transcript_variant	0.801[CEU]; 0.862[TSI]
rs271736	downstream_gene_variant	0.959[CEU]; 0.954[TSI]
rs823485	upstream_gene_variant	0.816[TSI]
rs907623	downstream_gene_variant	0.959[CEU]
rs271762	upstream_gene_variant	0.818[TSI]
rs271740	downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant	0.884[TSI]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Bergen, S. E.,2012	logistic regression:P-value > E-05	No significant association was observed in SZ.	Negative

Overlap with MDD from cross-disorder studies (count: 0)