SNP Report
Basic Info
| Name |
rs2236570
dbSNP
Ensembl
|
| Location |
chr1:147622086 - 147622086(1) |
| Variant Alleles |
A/G |
| Ancestral Allele |
G |
| Minor Allele |
A |
| Minor Allele Frequence |
0.280351 |
| Functional Annotation |
intron_variant.
|
| Consequence to Transcript |
intron_variant(ENST00000234739) |
| No. of Studies |
1 (Positive: 0; Negative: 1; Trend: 0) |
| Source |
Literature |
| Overlap with SZ? |
YES
|
|---|
| Overlap with MDD? |
YES
|
|---|
SNP related studies (count: 1)
SNP related genes (count: 1)
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.
Literature-origin SNPs (count: 0)
LD-proxies (count: 10)
| rs_ID |
Literature-origin SNPs with LD |
Functional Annotation |
r2[population] |
|
rs2275552
|
|
intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant |
0.894[CHD]
|
|
rs12037951
|
|
downstream_gene_variant; stop_lost |
0.839[CHD]; 0.868[JPT]
|
|
rs6674938
|
|
intron_variant; NMD_transcript_variant; non_coding_transcript_variant; upstream_gene_variant |
0.894[CHD]
|
|
rs17361839
|
|
downstream_gene_variant |
0.948[CHB]; 1.0[JPT]
|
|
rs597577
|
|
downstream_gene_variant; intron_variant |
1.0[CHB]; 1.0[JPT]
|
|
rs677977
|
|
downstream_gene_variant; intron_variant; non_coding_transcript_variant |
1.0[CHB]; 0.973[CHD]; 1.0[JPT]
|
|
rs12119079
|
|
intron_variant; NMD_transcript_variant; non_coding_transcript_variant |
0.894[CHD]
|
|
rs583583
|
|
intron_variant; non_coding_transcript_variant; upstream_gene_variant |
1.0[CHB]; 0.973[CHD]; 1.0[JPT]
|
|
rs613089
|
|
intron_variant; non_coding_transcript_variant; upstream_gene_variant |
0.89[CHB]; 0.86[CHD]; 1.0[JPT]
|
|
rs2153463
|
|
3_prime_UTR_variant; downstream_gene_variant; intron_variant; missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; synonymous_variant; upstream_gene_variant |
0.894[CHD]
|
Overlap with SZ from cross-disorder studies (count: 1)
| Reference |
Statistical Result |
Description |
Result Category |
| Li, J.,2011(b) |
Third-Stage Sample:for SZ, allele association P-value = 0.7, OR(95%CI)=0.97(0.85-1.11);Combined Third-Stage Sample, allele association P-value = 0.88, OR(98%CI)=1.00(0.93-1.06) |
No significant association was observed. |
Negative |
Overlap with MDD from cross-disorder studies (count: 1)
| Reference |
Statistical Result |
Description |
Result Category |
| Li, J.,2011(b) |
Third-Stage Sample:for MDD, allele association P-value = 0.78, OR(95%CI)=1.02(0.89-1.16) |
No significant association was observed. |
Negative
|
