BDgene

SNP Report

Basic Info
Name rs2254884 dbSNP Ensembl
Location chr9:104819468 - 104819468(1)
Variant Alleles A/C
Ancestral Allele A
Minor Allele C
Minor Allele Frequence 0.283347
Functional Annotation intron_variant.
Consequence to Transcript intron_variant(ENST00000374736)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Andreassen OA, 2013 Conditional FDR; SCZ loci given BD: FDR=0.032 for SCZ and BD Conditional FDR; SCZ loci given BD: FDR=0.032 for SCZ and BD To estimate the number of independent loci, we 'pruned' the ...... To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. More... Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 9q31 Mapped by Literature SNP

SNPs in LD with rs2254884 (count: 0) View in gBrowse (chr9:104819468..104819468 )

Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Andreassen OA, 2013 Conditional FDR; SCZ loci given BD: P-value=0.000117, FDR=0.203, FDR=0.032 for SCZ and BD To estimate the number of independent loci, we 'pruned' the associated SNPs (removed SNPs with linkage disequilibrium (LD)>0.2), and identified a total of 58 independent loci with a significance threshold of conditional FDR<0.32. Positive

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016