SNP Report

Basic Info

Name	rs37022 dbSNP Ensembl
Location	chrCHR_HSCHR5_3_CTG1:1413658 - 1413658(-1)
Variant Alleles	A/T
Ancestral Allele	A
Minor Allele	T
Minor Allele Frequence	0.355631
Functional Annotation	intron_variant; non_coding_transcript_variant; downstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000270349, ENST00000511750); non_coding_transcript_variant(ENST00000511750); downstream_gene_variant(ENST00000626610, ENST00000621716)
No. of Studies	3 (Positive: 1; Negative: 2; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 3)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2008 (b)	A/T	A	Allelic association of neurotransmission systems genes with ...... Allelic association of neurotransmission systems genes with bipolar disorder: TDT P-value = 0.0371, Gene-wide P-value = 0.2108 (P values were based on permutation for all SNPs in each gene). More...		Positive
Pinsonneault, J. K.,2011			Stanley sample: allele, X² P-value = 0.75, Fisher...... Stanley sample: allele, X² P-value = 0.75, Fisher's exact P-value = 0.85, OR=1.13, 95%CI=0.5-2.3 for BD; X² P-value = 0.81, Fisher's exact P-value = 0.86OR=0.91 for BD More...	No significant association was observed. No significant association was observed.	Negative
Mick, E., 2008		T	TDT X²(df=1)=1.14, P-value = 0.309, OR (95% CI)=1...... TDT X²(df=1)=1.14, P-value = 0.309, OR (95% CI)=1.06(0.72-1.57) More...		Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SLC6A3	solute carrier family 6 (neurotransmitter transporter), member 3	5p15.3	11(5/6/0)

SNPs in LD with rs37022 (count: 0) View in gBrowse (chrCHR_HSCHR5_3_CTG1:1413658..1413658 )

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Pinsonneault, J. K.,2011	Stanley sample:allele, X² P-value = 0.81, Fisher's exact P-value = 0.86OR=0.91 for SZ	No significant association was observed.	Negative

Overlap with MDD from cross-disorder studies (count: 0)