BDgene

SNP Report

Basic Info
Name rs3766512 dbSNP Ensembl
Location chr1:147625834 - 147625834(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.180911
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000234739); downstream_gene_variant(ENST00000609196)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? YES

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Li, J.,2011(b) C/T Third-Stage Sample: for BPD, allele association P-value = 0....... Third-Stage Sample: for BPD, allele association P-value = 0.19, OR(95%CI)=1.08(0.96-1.22) More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
ACP6 acid phosphatase 6, lysophosphatidic 1q21 1(1/0/0)
BCL9 B-cell CLL/lymphoma 9 1q21 1(1/0/0)

SNPs in LD with rs3766512 (count: 24) View in gBrowse (chr1:147624993..147665867 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 24)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Li, J.,2011(b) Third-Stage Sample:for SZ, allele association P-value = 0.23, OR(95%CI)=1.08(0.95-1.22);Combined Third-Stage Sample, allele association P-value = 0.01, OR(98%CI)=1.08(1.02-1.15) Significant association was observed in SZ. Positive

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Li, J.,2011(b) Third-Stage Sample:for MDD, allele association P-value = 0.13, OR(95%CI)=1.10(0.97-1.24) No significant association was observed. Negative