Gene Report

Basic Info
Approved Symbol ACAN
Previous Symbol MSK16, CSPG1, AGC1
Symbol Alias CSPGCP
Approved Name aggrecan
Previous Name chondroitin sulfate proteoglycan 1, "aggrecan 1"
Name Alias aggrecan proteoglycan
Location 15q26.1
Position chr15:88803443-88875354, 1
External Links HGNC: 319
Entrez Gene: 176
Ensembl: ENSG00000157766
UCSC: uc010upo.1
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
McAuley, E. Z., 2012 SNP: rs2280468 Nominally significant association (P < 0.05) was found with 1 SNP with BD. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 22)

GO terms by PBA (count: 3)

GO terms by database search (count: 19)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 17)

Related other genetic factors
Gene related SNPs (count: 1)

Literature-origin SNPs (count: 1)

LD-proxies (count: 0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 4)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 0)

Gene relationship with MDD

View in gBrowse

Region: chr15:88803443..88875354 View in gBrowse
View in gBrowse