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SNP Report
Basic Info
| Name | rs821663 dbSNP Ensembl | ||
|---|---|---|---|
| Location | chr1:231985476 - 231985476(1) | ||
| Variant Alleles | C/T | ||
| Ancestral Allele | T | ||
| Minor Allele | T | ||
| Minor Allele Frequence | 0.4373 | ||
| Functional Annotation | intron_variant; NMD_transcript_variant; non_coding_transcript_variant. | ||
| Consequence to Transcript | intron_variant(ENST00000366637, ENST00000422590, ENST00000427560, ENST00000439617, ENST00000535983, ENST00000620189, ENST00000622252); NMD_transcript_variant(ENST00000422590); non_coding_transcript_variant(ENST00000427560) | ||
| No. of Studies | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
| Overlap with SZ? | YES | ||
| Overlap with MDD? | NO | ||
SNP related studies (count: 1)
SNP related genes (count: 2)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| TSNAX | translin-associated factor X | 1q42.2 | 4(3/1/0) |
| DISC1 | disrupted in schizophrenia 1 | 1q42.1 | 18(10/7/1) |
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.
Literature-origin SNPs (count: 0)
LD-proxies (count: 14)
Overlap with SZ from cross-disorder studies (count: 1)
| Reference | Statistical Result | Description | Result Category |
|---|---|---|---|
| Thomson, P. A.,2005(a) | Single-Marker Analysis:allele frequency, for SZ, P-value = 0.12 | No significant association was observed. | Negative |
Overlap with MDD from cross-disorder studies (count: 0)