SNP Report

Basic Info

Name	rs10261327 dbSNP Ensembl
Location	chr7:21423210 - 21423210(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.492612
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000222584, ENST00000432066, ENST00000440636, ENST00000448246)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	YES
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Zhou, X.,2009	C/T		Allelic association: Caucasian Families for Bipolar Disorder...... Allelic association: Caucasian Families for Bipolar Disorder: TDT: Risk allele is C, MAF=0.46P-value = 0.379; Chinese Case-Controls for Bipolar Disorder: Risk allele is C, MAF=0.49P-value = 0.953 More...	No significant association was observed No significant association was observed	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
SP4	Sp4 transcription factor	7p15	1(1/0/0)

SNPs in LD with rs10261327 (count: 2) View in gBrowse (chr7:21399683..21423210 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs17144403		downstream_gene_variant	0.818[CHD]
rs17144407			0.908[CHD]; 0.867[JPT]

Overlap with SZ from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Zhou, X.,2009	Allelic association:Chinese Trios for Schizophrenia:TDT:Risk allele is C, MAF=0.471P-value = 0.908	No significant association was observed	Negative

Overlap with MDD from cross-disorder studies (count: 0)