BDgene

SNP Report

Basic Info
Name rs10261327 dbSNP Ensembl
Location chr7:21423210 - 21423210(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.492612
Functional Annotation upstream_gene_variant.
Consequence to Transcript upstream_gene_variant(ENST00000222584, ENST00000432066, ENST00000440636, ENST00000448246)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Zhou, X.,2009 C/T Allelic association: Caucasian Families for Bipolar Disorder...... Allelic association: Caucasian Families for Bipolar Disorder: TDT: Risk allele is C, MAF=0.46P-value = 0.379; Chinese Case-Controls for Bipolar Disorder: Risk allele is C, MAF=0.49P-value = 0.953 More... No significant association was observed No significant association was observed Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SP4 Sp4 transcription factor 7p15 1(1/0/0)

SNPs in LD with rs10261327 (count: 2) View in gBrowse (chr7:21399683..21423210 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 2)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Zhou, X.,2009 Allelic association:Chinese Trios for Schizophrenia:TDT:Risk allele is C, MAF=0.471P-value = 0.908 No significant association was observed Negative

Overlap with MDD from cross-disorder studies (count: 0)