BDgene

SNP Report

Basic Info
Name rs10276352 dbSNP Ensembl
Location chr7:21481615 - 21481615(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.425919
Functional Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant.
Consequence to Transcript downstream_gene_variant(ENST00000432066); intron_variant(ENST00000222584, ENST00000448246); NMD_transcript_variant(ENST00000448246)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? YES
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Zhou, X.,2009 A/G Allelic association: Caucasian Families for Bipolar Disorder...... Allelic association: Caucasian Families for Bipolar Disorder: TDT: Risk allele is G, MAF=0.44P-value = 0.102; Chinese Case-Controls for Bipolar Disorder: Risk allele is G, MAF=0.28, P-value = 0.095 More... No significant association was observed. No significant association was observed. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SP4 Sp4 transcription factor 7p15 1(1/0/0)

SNPs in LD with rs10276352 (count: 7) View in gBrowse (chr7:21436570..21481615 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 7)


Overlap with SZ from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Zhou, X.,2009 Allelic association:Chinese Trios for Schizophrenia:TDT:Risk allele is G, MAF=0.281, P-value = 0.526 No significant association was observed Negative

Overlap with MDD from cross-disorder studies (count: 0)