Gene Report

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Basic Info

Approved Symbol	GGTA1P
Previous Symbol	GLYT2, GGTA, GGTA1
Approved Name	glycoprotein, alpha-galactosyltransferase 1 pseudogene
Previous Name	glycoprotein, alpha-galactosyltransferase 1
Location	9q33.2
Position	chr9:121444991-121500027, -1
External Links	HGNC: 4253 Entrez Gene: 2681 Ensembl: ENSG00000204136 UCSC: uc004bll.1
No. of Studies	1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ?	YES
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Rajkumar, A. P., 2014	SNP: rs4240467	The SNP related to this gene showed significant association with BD.	Positive	Comment on Study

Gene functional annotation

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0016758	transferase activity, transferring hexosyl groups	molecular function	IEA	2
GO:0016021	integral component of membrane	cellular component	IEA	219
GO:0006749	glutathione metabolic process	biological process	TAS[18357469]	5

ID	Name	Type	Evidence[PMID]	No. of Genes in BDgene
GO:0031985	Golgi cisterna	cellular component	ISS	3
GO:0033580	protein galactosylation at cell surface	biological process	ISS	1
GO:0019370	leukotriene biosynthetic process	biological process	ISS	3
GO:0003840	gamma-glutamyltransferase activity	molecular function	TAS[18357469]	1
GO:0031362	anchored component of external side of plasma membrane	cellular component	TAS[18357469]	1
GO:0032580	Golgi cisterna membrane	cellular component	IEA	2

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs4240467	chr9:121548011 - 121548011(1)		1(1/0/0)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 9	chr9:0-138394717	3 (0/3/0)
9q33	chr9:114900000-127500000	1 (0/0/1)
9q32-q33	chr9:112100000-127500000	1 (0/0/1)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Reference	Description	Result Category
25053281	SNPs in the chromosome 9q33.2 breakpoint region were not significantly associated with SZ (p>0.15).	Negative

Gene relationship with MDD

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Region: chr9:121444991..121500027 View in gBrowse