BDgene

Gene Report

Basic Info
Approved Symbol RPTOR
Symbol Alias KOG1, Mip1, KIAA1303, raptor
Approved Name regulatory associated protein of MTOR, complex 1
Name Alias regulatory associated protein of mTOR
Location 17q25.3
Position chr17:80544819-80966371, 1
External Links HGNC: 30287
Entrez Gene: 57521
Ensembl: ENSG00000141564
UCSC: uc002jyt.1
No. of Studies 2 (Positive: 1; Negative: 1; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Bergen, S. E.,2012 SNP: rs11150863 No significant association was observed in BD. Negative Comment on Study
Rajkumar, A. P., 2014 SNP: rs7218584, rs11150746, rs3923310 After Bonferroni correction, and that the association between RPTOR and BD was borderline significant. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 30)

GO terms by PBA (count: 1)

GO terms by database search (count: 29)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 7)

Related other genetic factors
Gene related SNPs (count: 34)

Literature-origin SNPs (count: 4)

LD-proxies (count: 30)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 2)

Overlap with SZ from candidate gene intersection analysis (count: 0)


Gene relationship with MDD

View in gBrowse

Region: chr17:80544819..80966371 View in gBrowse
View in gBrowse