BDgene

Gene Report

Basic Info
Approved Symbol GNB1L
Symbol Alias GY2, WDR14
Approved Name guanine nucleotide binding protein (G protein), beta polypeptide 1-like
Location 22q11.2
Position chr22:19783224-19854939, -1
External Links HGNC: 4397
Entrez Gene: 54584
Ensembl: ENSG00000185838
UCSC: uc002zqf.1
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? YES
Overlap with MDD? YES
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Li, Y.,2011 SNP: rs1468089, rs2269726, rs5746832, rs5748425, rs5748427, rs5748432, rs748806 Our findings suggests that GNB1L is linked with bipolar disorder and schizophrenia and not with major depressive disorder. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 6)

GO terms by PBA (count: 0)

GO terms by database search (count: 6)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 38)

Literature-origin SNPs (count: 8)

LD-proxies (count: 30)


Gene related CNVs (count: 1)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 1)

Overlap with SZ from candidate gene intersection analysis (count: 4)


Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 1)

Overlap with MDD from candidate gene intersection analysis (count: 0)


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Region: chr22:19783224..19854939 View in gBrowse
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